Photic and circadian expression of luciferase in mPeriod1 - luc transgenic mice in vivo

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Molecular Bases for Circadian Clocks

1999 • 2,823 citations

Matlnd and Matlnspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

1995 • 2,642 citations

Role of the CLOCK Protein in the Mammalian Circadian Mechanism

1998 • 1,915 citations

Resetting Central and Peripheral Circadian Oscillators in Transgenic Rats

2000 • 1,844 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Mutagenesis and Mapping of a Mouse Gene, Clock , Essential for Circadian Behavior

1994 • 1,570 citations

mCRY1 and mCRY2 Are Essential Components of the Negative Limb of the Circadian Clock Feedback Loop

1999 • 1,558 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

The cryb Mutation Identifies Cryptochrome as a Circadian Photoreceptor in Drosophila

1998 • 952 citations

A Molecular Mechanism Regulating Rhythmic Output from the Suprachiasmatic Circadian Clock

1999 • 894 citations

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.

1985 • 888 citations

A Differential Response of Two Putative Mammalian Circadian Regulators, mper1and mper2, to Light

1997 • 883 citations

Differential Functions of mPer1, mPer2, and mPer3 in the SCN Circadian Clock

2001 • 876 citations

Nonredundant Roles of the mPer1 and mPer2 Genes in the Mammalian Circadian Clock

2001 • 873 citations

Light-Induced Resetting of a Mammalian Circadian Clock Is Associated with Rapid Induction of the Transcript

1997 • 866 citations

Messenger RNA degradation in eukaryotes

1993 • 858 citations

Positional Syntenic Cloning and Functional Characterization of the Mammalian Circadian Mutation tau

2000 • 850 citations

Regulation of CREB Phosphorylation in the Suprachiasmatic Nucleus by Light and a Circadian Clock

1993 • 817 citations

Circadian oscillation of a mammalian homologue of the Drosophila period gene

1997 • 782 citations

Calcium Influx via the NMDA Receptor Induces Immediate Early Gene Transcription by a MAP Kinase/ERK-Dependent Mechanism

1996 • 781 citations

Two period Homologs: Circadian Expression and Photic Regulation in the Suprachiasmatic Nuclei

1997 • 763 citations

Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences

1988 • 691 citations

Differential regulation of mammalian Period genes and circadian rhythmicity by cryptochromes 1 and 2

1999 • 668 citations

Functional Identification of the Mouse Circadian Clock Gene by Transgenic BAC Rescue

1997 • 664 citations

RIGUI, a Putative Mammalian Ortholog of the Drosophila period Gene

1997 • 664 citations

Independent Photoreceptive Circadian Clocks Throughout Drosophila

1997 • 628 citations

Light-Independent Role of CRY1 and CRY2 in the Mammalian Circadian Clock

1999 • 613 citations

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

1989 • 601 citations

Circadian Clock Mutants in Arabidopsis Identified by Luciferase Imaging

1995 • 596 citations

Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.

1991 • 546 citations

Molecular Genetics of Circadian Rhythms in Mammals

2000 • 541 citations

The Nonamer UUAUUUAUU Is the Key AU-Rich Sequence Motif That Mediates mRNA Degradation

1995 • 524 citations

Vitamin B ₂ -based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals

1998 • 402 citations

Photic Induction of mPer1 and mPer2 in Cry -Deficient Mice Lacking a Biological Clock

1999 • 373 citations

Mammalian Circadian Autoregulatory Loop

1998 • 347 citations

Analysis of Clock Proteins in Mouse SCN Demonstrates Phylogenetic Divergence of the Circadian Clockwork and Resetting Mechanisms

2000 • 343 citations

Inhibition of Light- or Glutamate-InducedmPer1Expression Represses the Phase Shifts into the Mouse Circadian Locomotor and Suprachiasmatic Firing Rhythms

1999 • 262 citations

Post-transcriptional regulation contributes to Drosophila clock gene mRNA cycling

1997 • 257 citations

Circadian rhythm genetics: from flies to mice to humans

2000 • 231 citations

Interplay of two functionally and structurally distinct domains of the c-fos AU-rich element specifies its mRNA-destabilizing function

1994 • 184 citations

Differential Regulation of mPER1 and mTIM Proteins in the Mouse Suprachiasmatic Nuclei: New Insights into a Core Clock Mechanism

1999 • 175 citations

Circadian Rhythms in Rapidly Dividing Cyanobacteria

1997 • 156 citations

The 5′ upstream region of mPer1 gene contains two promoters and is responsible for circadian oscillation

2000 • 151 citations

Light, immediate-early genes, and circadian rhythms

1996 • 145 citations

GFP fluorescence reports Period 1 circadian gene regulation in the mammalian biological clock

2000 • 131 citations

Temporal and spatial expression patterns of transgenes containing increasing amounts of the Drosophila clock gene period and a lacZ reporter: mapping elements of the PER protein involved in circadian cycling.

1997 • 114 citations

View of a mouse clock gene ticking

2001 • 112 citations

Temporal and Spatial Expression Patterns of Transgenes Containing Increasing Amounts of theDrosophilaClock Geneperiodand alacZReporter: Mapping Elements of the PER Protein Involved in Circadian Cycling

1997 • 103 citations

Circadian rhythms: molecular basis of the clock

1998 • 77 citations

The Destabilizing Elements in the Coding Region of c-fos mRNA Are Recognized as RNA

1993 • 71 citations