Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

1987 • 2,788 citations

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

1989 • 1,744 citations

A NEW SPECTROPHOTOMETRIC METHOD FOR THE DETECTION AND DETERMINATION OF KETO SUGARS AND TRIOSES

1951 • 1,101 citations

Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen.

1994 • 334 citations

P-Glycoprotein Substrates and Antagonists Cluster into Two Distinct Groups

1997 • 229 citations

Recent advances in carrier-mediated hepatic uptake and biliary excretion of xenobiotics.

1996 • 218 citations

Current concepts on the pathophysiology of acute renal failure

1978 • 191 citations

Transport of rhodamine 123, a P-glycoprotein substrate, across rat intestine and Caco-2 cell monolayers in the presence of cytochrome P-450 3A-related compounds.

1999 • 181 citations

Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells

1998 • 143 citations

Characterization of Binding Site of Uremic Toxins on Human Serum Albumin.

1995 • 122 citations

Antiestrogens and steroid hormones: Substrates of the human P-glycoprotein

1994 • 115 citations

Effect of the P-Glycoprotein Inhibitor, Cyclosporine A, on the Distribution of Rhodamine-123 to the Brain: An in Vivo Microdialysis Study in Freely Moving Rats

1995 • 83 citations

Interaction between two dicarboxylate endogenous substances, bilirubin and an uremic toxin, 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid, on human serum albumin.

1999 • 45 citations

Transport of p-aminohippurate, tetraethylammonium and D-glucose in renal brush border membranes from rats with acute renal failure.

1985 • 39 citations

Renal Excretion of Rhodamine 123, a P-Glycoprotein Substrate, in Rats with Glycerol-induced Acute Renal Failure

1998 • 37 citations

Glomerular hemodynamics in established glycerol-induced acute renal failure in the rat.

1989 • 32 citations

An experimental study of altered nitric oxide metabolism as a mechanism of cyclosporin-induced renal vasoconstriction

1995 • 32 citations

Models of Glycerol-Induced Acute Renal Failure in Rats

1993 • 30 citations

Plasma, Urinary, and Erythrocyte Concentrations of Guanidino Compounds in Patients with Chronic Renal Failure

1999 • 27 citations

New Mechanisms of Hormone Secretion: MDR-Like Gene Products as Extrusion Pumps for Hormones?

1992 • 26 citations

Renal handling of drugs in renal failure. I: Differential effects of uranyl nitrate- and glycerol-induced acute renal failure on renal excretion of TEAB and PAH in rats.

1988 • 26 citations

Modulators of the multidrug-transporter, P-glycoprotein, exist in the human plasma

1990 • 25 citations

Effects of glycerol-induced acute renal failure on tissue glutathione and glutathione-dependent enzymes in the rat.

1991 • 23 citations

Role of P-glycoprotein in distribution of rhodamine 123 into aqueous humor in rabbits

1999 • 23 citations

Distribution of Ciprofloxacin into the Central Nervous System in Rats with Acute Renal or Hepatic Failure

1999 • 19 citations

Early Detection of Acute Tubular Injury with Diffusion-Weighted Magnetic Resonance Imaging in a Rat Model of Myohemoglobinuric Acute Renal Failure

1996 • 16 citations

Pharmacokinetics and biliary excretion of bromosulphophthalein, [³H]‐ouabain and [³H]‐taurocholic acid in rats with glycerol‐induced acute renal failure

1984 • 15 citations

Interaction of P-glycoprotein with a hydrophobic component of rat urine

1992 • 13 citations

Decreased transport of p-aminohippurate in renal basolateral membranes isolated from rats with acute renal failure.

1989 • 9 citations

Role of P-glycoprotein in ocular clearance of rhodamine 123 in rabbits.

2000 • 7 citations

Regional differences in vasculotoxic effects of cyclosporin in rats

1995 • 7 citations

[Hepatic dysfunction in myoglobinuric acute renal failure (rhabdomyolysis)--experimental study in rats].

1996 • 2 citations