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Systemic hormonal and physiological abnormalities in anxiety disorders

Data up to Jan 2025

Published1988
Citations89
References232

Total Citations Per Year

Abstract

References (232)

A cognitive approach to panic

1986 • 2,371 citations

Stress Hormones: Their Interaction and Regulation

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Williams' Textbook of Endocrinology.

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Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised

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Arrhythmias documented by 24 hour continuous electrocardiographic monitoring in 50 male medical students without apparent heart disease

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Noradrenergic Function in Panic Anxiety

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Neurotransmitter regulation of anterior pituitary hormones.

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A psychophysiological analysis of fear modification using an automated desensitization procedure.

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Serotonin function in anxiety

1987 • 467 citations

Integrative functions of the autonomic nervous system

1980 • 434 citations

Increased Anxiogenic Effects of Caffeine in Panic Disorders

1985 • 427 citations

Obsessive-compulsive disorder: psychobiological approaches to diagnosis, treatment, and pathophysiology

1987 • 421 citations

Lactate Provocation of Panic Attacks

1985 • 381 citations

Psychobiology of stress : a study of coping men

1978 • 364 citations

Response to hyperventilation in a group of patients with panic disorder

1984 • 355 citations

Yohimbine induced anxiety and increased noradrenergic function in humans: Effects of diazepam and clonidine

1983 • 350 citations

Peripheral, autonomic regulation of locus coeruleus noradrenergic neurons in brain: putative implications for psychiatry and psychopharmacology

1987 • 342 citations

Physiological Measures, Sedative Drugs, and Morbid Anxiety

1966 • 334 citations

Neurobiological mechanisms of panic anxiety: biochemical and behavioral correlates of yohimbine-induced panic attacks

1987 • 303 citations

Abnormal Regulation of Noradrenergic Function in Panic Disorders

1986 • 301 citations

Nervous Control of Cardiovascular Function

1985 • 263 citations

Physiological measures, sedative drugs, and morbid anxiety

1966 • 261 citations

Adrenergic Function in Patients With Panic Anxiety

1984 • 260 citations

Buspirone: review of its pharmacology and current perspectives on its mechanism of action

1986 • 255 citations

Resting Plasma Catecholamine Concentrations in Patients With Depression and Anxiety

1971 • 249 citations

Cardiovascular Control by Cholinergic Mechanisms in the Central Nervous System

1982 • 239 citations

Hyperventilation Syndromes

1982 • 229 citations

Neuroendocrine tests of monoamine function in man: a review of basic theory and its application to the study of depressive illness

1980 • 227 citations

Premenstrual syndromes: overview from a methodologic perspective

1984 • 225 citations

Effects of Clonidine on Anxiety Disorders

1981 • 223 citations

Behavior and circulating catecholamines

1971 • 210 citations

The corticotropin-releasing hormone stimulation test in patients with panic disorder

1986 • 207 citations

Arrhythmias documented by 24-hour continuous ambulatory electrocardiographic monitoring in young women without apparent heart disease

1981 • 206 citations

Palmar skin conductance measures in anxiety and phobic states

1967 • 204 citations

NEUROCIRCULATORY ASTHENIA (ANXIETY NEUROSIS, EFFORT SYNDROME, NEURASTHENIA)

1950 • 196 citations

Carbon Dioxide Sensitivity in Panic Anxiety

1986 • 195 citations

Central Neural Integration for the Control of Autonomic Responses Associated with Emotion

1984 • 191 citations

Ambulatory heart rate changes in patients with panic attacks

1986 • 191 citations

Situational Panic Attacks

1987 • 188 citations

Physiological responses in blood phobics

1984 • 179 citations

Hyperventilation: The tip and the iceberg

1975 • 173 citations

Imaging of [11C]-labelled RO 15-1788 binding to benzodiazepine receptors in the human brain by positron emission tomography

1985 • 173 citations

Endocrine and cardiovascular responses during phobic anxiety.

1985 • 171 citations

The psychophysiology of mental illness

1975 • 171 citations

The benzodiazepine--GABA--chloride ionophore receptor complex: common site of minor tranquilizer action.

1981 • 170 citations

Neuroendocrine correlates of lactate-induced anxiety and their response to chronic alprazolam therapy

1986 • 170 citations

SYMPTOMS OF ANXIETY AND TENSION AND THE ACCOMPANYING PHYSIOLOGICAL CHANGES IN THE MUSCULAR SYSTEM

1954 • 162 citations

Metabolic studies in mitral valve prolapse syndrome. A neuroendocrine--cardiovascular process.

1980 • 161 citations

Some Biochemical Correlates of Panic Attacks with Agoraphobia and Their Response to a New Treatment

1984 • 161 citations

Clinical Neuroendocrinology. A Pathophysiological Approach.

1980 • 159 citations

Life Situations, Emotions, and Neurocirculatory Asthenia (Anxiety Neurosis, Neurasthenia, Effort Syndrome)

1951 • 157 citations

Endocrine and physiological changes during “spontaneous” panic attacks

1987 • 155 citations

Endocrine Responses to Stressful Psychological Events

1980 • 155 citations

Behavioral Stress and Cardiac Arrhythmias

1984 • 152 citations

Physiological changes during spontaneous panic attacks

1970 • 152 citations

Panic-Induced Elevation of Plasma MHPG Levels in Phobic-Anxious Patients

1983 • 147 citations

Neurotransmitters in Anxiety

1982 • 144 citations

Noradrenergic Function and the Mechanism of Action of Antianxiety Treatment

1985 • 142 citations

Autonomic dysfunction in women with mitral valve prolapse syndrome.

1979 • 137 citations

Ambulatory Monitoring of Panic Disorder

1985 • 128 citations

Dysautonomia in mitral valve prolapse

1979 • 126 citations

The dexamethasone suppression test in panic disorder and agoraphobia

1982 • 125 citations

Psychiatric progress

1984 • 125 citations

Nervous control of cardiovascular function

1984 • 123 citations

Benzodiazepine receptors in “emotional” and “non-emotional” mice: Comparison of four strains

1979 • 120 citations

Adrenergic hyperactivity and cardiac abnormality in primary disorders of sleep

1980 • 114 citations

Awareness of cardiac function in anxious, phobic and hypochondriacal patients

1980 • 113 citations

Neurophysiology and neuropharmacology of cardiovascular regulation and stress

1981 • 112 citations

Physiological and psychological measures in anxious patients

1974 • 111 citations

Stimulation response to corticotropin-releasing hormone (CRH) in patients with depression, alcoholism and panic disorder.

1987 • 108 citations

Synchronous and desynchronous changes during fear reduction

1979 • 107 citations

Sweating and its Disorders

1983 • 106 citations

Blunted growth hormone response to clonidine in panic disorder patients

1986 • 105 citations

Cortisol and Growth Hormone Responses to Psychological Stress during the Menstrual Cycle

1977 • 102 citations

Autonomic characteristics of agoraphobia with panic attacks

1986 • 102 citations

The biological basis of anxiety

1985 • 99 citations

Abnormal cardiovascular regulation in the mitral valve prolapse syndrome

1983 • 99 citations

Corticosteroid Responses to Hospital Admission

1965 • 99 citations

Platelet α2-Adrenergic Receptor Binding and Plasma Catecholamines

1984 • 98 citations

Buspirone, a non-benzodiazepine anxiolytic, increases locus coeruleus noradrenergic neuronal activity

1982 • 98 citations

Increased plasma catecholamine levels in patients with symptomatic mitral valve prolapse

1982 • 97 citations

Noradrenergic Function and the Mechanism of Action of Antianxiety Treatment

1985 • 96 citations

Caffeine: relationship to human anxiety, plasma MHPG and cortisol.

1984 • 95 citations

Sympathetic nervous system activity in panic disorder

1987 • 94 citations

The DST in psychiatric outpatients with generalized anxiety disorder, panic disorder, or primary affective disorder

1985 • 90 citations

Serotonin Function in Panic Disorders

1986 • 89 citations

QT interval prolongation and increased plasma catecholamine levels in patients with mitral valve prolapse

1983 • 87 citations

Panic attacks and the dexamethasone suppression test

1983 • 85 citations

ANXIETY

1982 • 84 citations

The Magnitude of Premenstrual Anxiety and Depression

1976 • 84 citations

Blood Gas Changes and Hypophosphatemia in Lactate-Induced Panic

1986 • 82 citations

Basic and clinical aspects of adenosinergic neuromodulation

1985 • 81 citations

Effect of pregnancy on panic attacks

1987 • 81 citations

Phenomenology and treatment of anxiety

1980 • 79 citations

Plasma β-endorphin, pain thresholds and anxiety levels across the human menstrual cycle

1984 • 79 citations

Adrenal Cortical Function in Anxious Human Subjects

1956 • 78 citations

Dexamethasone suppression tests in patients with panic disorder

1983 • 78 citations

Depression and anxiety associated with hyperthyroidism: Response to antithyroid therapy

1986 • 77 citations

Symptom profiles of patients with DSM-III anxiety disorders

1986 • 76 citations

Blood Lactate Concentration in Relation to Absolute and Relative Work Load in Normal Men, and in Mitral Stenosis, Atrial Septal Defect and Vasoregulatory Asthenia1

1959 • 76 citations

Cortisol excretion during the defense reaction in humans.

1985 • 76 citations

Naloxone administration in obsessive-compulsive disorder: report of two cases

1983 • 75 citations

Effects of naloxone on patients with panic attacks

1984 • 72 citations

Mitral valve prolapse syndrome: The effect of adrenergic stimulation

1983 • 71 citations

Analysis of single, double-blind procedures, maintenance of placebo effects, and drug-induced dyskinesia with mentally retarded persons--a brief report [proceedings].

1981 • 70 citations

Menstrual fluctuation in the symptoms of panic anxiety

1988 • 69 citations

Hyperventilation Syndrome

1978 • 69 citations

MHPG: Basic Mechanisms and Psychopathology

1983 • 68 citations

Somatic symptoms of anxiety: Comparison of self-report and physiological measures

1986 • 68 citations

Measurement of Anxiety by Forearm Blood Flow

1966 • 67 citations

Emotional influences on breathing and breathlessness

1985 • 66 citations

Patterns of desynchrony in agoraphobia: A preliminary report

1980 • 65 citations

Anxiety and Plasma Cortisol at the Crest of the Circadian Cycle: Reappraisal of a Classical Hypothesis

1978 • 64 citations

Growth Hormone and Cortisol Responses to Psychological Stress: Comparison of Normal and Neurotic Subjects

1976 • 63 citations

The effects of benzodiazepine and non-benzodiazepine anxiolytics on locus coeruleus unit activity

1983 • 63 citations

Psychophysiological Factors in Panic Disorder

1984 • 62 citations

Decreased skin conductance response habituation in chronically anxious patients

1975 • 60 citations

MHPG: Basic Mechanisms and Psychopathology

1985 • 58 citations

A Comparison of the Exercise Response in Anxiety States and Normal Controls

1946 • 58 citations

Catecholamines and monoamine oxidase activity in anxiety

1981 • 55 citations

Anxiety and caffeine consumption in people with anxiety disorders

1985 • 55 citations

Ambulatory heart rate changes during panic attacks

1982 • 54 citations

Plasma HVA and anxiety in patients with panic disorder

1986 • 53 citations

"Flooding in vivo" during the circadian phase of minimal cortisol secretion: anxiety and therapeutic success without adrenal cortical activation.

1976 • 53 citations

Catecholamines and anxiety

1982 • 52 citations

Diagnosis and treatment of the hyperventilation syndrome

1979 • 52 citations

Anxiety and Mood Fluctuation During the Normal Menstrual Cycle

1982 • 52 citations

Physiological Responses in Anxious Women Patients

1964 • 48 citations

Increased central alpha2-adrenoceptor sensitivity in panic disorder

1986 • 48 citations

The relationship between psychological and physiological measures of anxiety

1978 • 47 citations

Pathophysiology of panic: a review of pharmacologic provocative tests and naturalistic monitoring data.

1986 • 47 citations

Cardiac rate and rhythm in panic patients

1987 • 47 citations

Platelet binding studies in panic disorder

1987 • 46 citations

A Clinical and Physiological Relationship between Anxiety and Depression

1969 • 46 citations

Modern trends in psychosomatic medicine—3

1977 • 46 citations

Peptides, hormones and behavior

1984 • 46 citations

Influence of exercise on anxiety level in patients with anxiety disorders

1986 • 46 citations

Anxiety Induced by Flooding Therapy for Phobias Does Not Elicit Prolactin Secretory Response*

1980 • 45 citations

Cardiac arrhythmias in the monkey during classically conditioned fear and excitement

1981 • 45 citations

Effects of naloxone on normals and chronically anxious patients.

1981 • 45 citations

Habituation of physiological responses in anxiety.

1980 • 44 citations

Fainting on exposure to phobic stimuli

1983 • 44 citations

Platelet [3H]imipramine binding in patients with panic disorder

1987 • 43 citations

Urinary catecholamines and mitral valve prolapse in panic-anxiety patients

1985 • 43 citations

Platelet serotonin uptake in panic disorder

1986 • 42 citations

Cardiovascular Response to Stress in Man

1984 • 42 citations

The relationship between anxiety and the level of peripheral vasomotor activity

1956 • 42 citations

Adrenal Cortical Function in Anxious Human Subjects

1957 • 42 citations

Norepinephrine Challenges in Panic Patients

1986 • 42 citations

The prevalence of mitral valve prolapse in patients with panic disorders

1986 • 42 citations

The Dexamethasone Suppression Test in Generalised Anxiety Disorder

1986 • 41 citations

Catechol-O-methyltransferase and catecholamines in anxiety and relaxation

1980 • 41 citations

Lactate infusions: The role of baseline anxiety

1987 • 40 citations

Anxiety and Emotions: Physiological Basis and Treatment

1981 • 40 citations

Urinary free cortisol levels in anxiety

1983 • 39 citations

Mind and Cancer Prognosis

1980 • 38 citations

Autonomic reactions to social and neutral stimuli in subjects high and low in public speaking fear

1986 • 38 citations

Platelet [3H]Imipramine binding in generalized anxiety disorder, panic disorder, and agoraphobia with panic attacks

1987 • 37 citations

Catechol-O-Methyl Transferase Activity in Patients with Depressive Illness and Anxiety States

1978 • 37 citations

Sources of Variance in Clinical Studies of MHPG

1983 • 37 citations

The psychophysiology of mental illness

1976 • 36 citations

A comparison of inpatients with primary unipolar depression and depression secondary to anxiety

1980 • 36 citations

Emotion and Blood-Pressure By

1959 • 35 citations

Generalized Anxiety Disorder

1985 • 35 citations

Relationships between Central Nervous System Noradrenergic Function and Plasma and Urinary MHPG and Other Norepinephrine Metabolites

1983 • 35 citations

Panic disorder and major depression: biological relationships.

1985 • 35 citations

Beta-Adrenergic Blocking Drugs in Anxiety and Stress

1985 • 35 citations

Glucose tolerance testing in panic disorder

1984 • 35 citations

Exercise and Anxiety Neurosis

1979 • 34 citations

The Dexamethasone Suppression Test in Agoraphobia

1985 • 34 citations

THE ELECTROCARDIOGRAM IN NEUROCIRCULATORY ASTHENIA (ANXIETY, NEUROSIS OR NEURASTHENIA): A STUDY OF 203 NEUROCIRCULATORY ASTHENIA PATIENTS AND 757 HEALTHY CONTROLS IN THE FRAMINGHAM STUDY

1958 • 34 citations

Regulatory role of gamma-aminobutyric acid in pituitary hormone secretion

1982 • 33 citations

Mitral Valve Prolapse and Panic Disorder

1985 • 33 citations

Platelet MAO-B activity in anxiety and depression

1986 • 31 citations

Plasma catecholamines at rest and exercise in subjects with high- and low-trait anxiety.

1986 • 31 citations

Dexamethasone suppression test in patients with panic attacks

1986 • 31 citations

CENTRAL AND PERIPHERAL CORRELATES OF ANXIETY

1976 • 30 citations

Prevalence of mitral valve prolapse in panic disorder: effect of echocardiographic criteria.

1986 • 30 citations

Plasma MHPG levels in lactate and isoproterenol anxiety states

1987 • 30 citations

Plasma Growth Hormone: Effect of Anxiety During Flooding in Vivo

1979 • 30 citations

Anxiety and Emotions: Physiological Basis and Treatment

1980 • 30 citations

Studies in Neurocirculatory Asthenia (Da Costa's Syndrome): I. Variations with Regard to Symptoms and some Pathophysiological Signs

1962 • 29 citations

Differentiation of anxious patients by two-dimensional echocardiographic evaluation of the mitral valve

1986 • 29 citations

The effect of phobic anxiety on plasma β-endorphin: a single-subject experiment

1986 • 27 citations

The electrocardiogram in neurocirculatory asthenia, anxiety neurosis, or effort syndrome

1947 • 27 citations

Thyroid dysfunction in phobic patients

1984 • 26 citations

The relationship of plasma free MHPG to anxiety and psycho-physical pain in normal volunteers.

1982 • 26 citations

Mitral valve prolapse and borderline hypertension.

1979 • 24 citations

Interactions of Stress, Salt, and Blood Pressure

1984 • 24 citations

Mitral valve prolapse and thyroid abnormalities in patients with panic attacks

1987 • 23 citations

Biological stress responses in high and low trait anxious students

1985 • 23 citations

Physiological and subjective measures of anxiety during flooding

1982 • 23 citations

Platelet monoamine oxidase activity in patients with panic disorder

1985 • 22 citations

Insulin-induced hypoglycemia and panic attacks

1986 • 22 citations

Platelet serotonin levels in panic disorder

1987 • 21 citations

Plasma glucose and lactic acid alterations in response to a stressful exam

1979 • 21 citations

Pharmacological Responsiveness of Sweat Glands in Anxious Patients and Healthy Volunteers

1982 • 21 citations

Hematocrit and anxiety

1986 • 20 citations

MAO, DBH and COMT: the effect of anxiety.

1980 • 20 citations

Phobic anxiety does not affect plasma levels of thyroid stimulating hormone in man

1982 • 20 citations

Comparison of biochemical properties of platelet monoamine oxidase in mentally disordered and healthy individuals

1982 • 20 citations

Hyperthyroidism and panic attacks

1983 • 19 citations

Prolactin response to the cold pressor test in patients with panic attacks

1983 • 19 citations

Anxiety states: relationship to atmospheric cations and serotonin.

1983 • 19 citations

The pineal hormone melatonin in panic disorder

1987 • 18 citations

Screening for thalassaemia and/or iron deficiency: Evaluation of some discrimination functions

1984 • 18 citations

Preinfusion anxiety predicts lactate-induced panic attacks in normal controls.

1987 • 17 citations

Physiological effects of performing a difficult task in patients with anxiety states

1964 • 17 citations

Anxiety and serum prolactin

1979 • 15 citations

Plasma Cyclic Nucleotide Responses to Psychological Stress in Normal and Neurotic Subjects

1983 • 14 citations

Neuroendocrine abnormalities in panic disorder.

1985 • 14 citations

Electrodermal psychophysiology of anxiety disorder: Orienting response and spontaneous fluctuations

1987 • 13 citations

The influence of sodium amytal on the respiratory abnormalities of anxious psychiatric patients

1960 • 13 citations

Mitral valve abnormalities and catecholamine activity in anxious patients

1987 • 13 citations

Hemodynamic reactions to circulatory stress tests in patients with neurocirculatory dystonia.

1984 • 13 citations

The nervous body: An introduction to the autonomic nervous system and behaviour

1979 • 12 citations

Acetylcholinesterase and pseudocholinesterase activities in anxiety

1980 • 12 citations

Some physiologic antecedents of adult mental health

1987 • 11 citations

Mitral valve prolapse in a psychiatric setting diagnostic assessment research and clinical implications

1986 • 9 citations

Physiological Correlates of Anxiety a Preliminary Investigation of the Orienting Reflex

1964 • 9 citations

Catecholamine and dopamine-β-hydroxylase in anxiety

1981 • 8 citations

Forearm Blood Flow in Normal Subjects and Patients with Phobic Anxiety States

1965 • 8 citations

Self-report and physiologic responding during in vivo flooding

1980 • 8 citations

Assessment Methods and the Differential Diagnosis of Anxiety

1981 • 8 citations

Phobia Questionnaire Responses and Urine Catecholamines

1970 • 8 citations

The Physiological and Pharmacological Control of Anterior Pituitary Hormone Secretion

1984 • 6 citations

Serum dopamine-beta-hydroxylase activity in depression and anxiety.

1984 • 6 citations

Symptoms of insulin-induced hypoglycemia in normal subjects

1988 • 3 citations

Urinary 3'5' cyclic adenosine monophosphate (cAMP) as a measure of anxiety.

1977 • 3 citations

Insulin levels during lactate infusion

1984 • 3 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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