An explanation for lagging strand replication: Polymerase hopping among DNA sliding clamps

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1994 • 1,669 citations

Three-dimensional structure of the β subunit of E. coli DNA polymerase III holoenzyme: A sliding DNA clamp

1992 • 748 citations

Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme

1991 • 420 citations

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.

1994 • 415 citations

Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes.

1993 • 362 citations

Variability of the intracellular ionic environment of Escherichia coli. Differences between in vitro and in vivo effects of ion concentrations on protein-DNA interactions and gene expression.

1987 • 270 citations

The in vitro replication of DNA containing the SV40 origin.

1990 • 268 citations

Sliding Clamps of DNA Polymerases

1993 • 250 citations

Efficient in vitro replication of double-stranded DNA templates by a purified T4 bacteriophage replication system.

1980 • 203 citations

Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. I. Multiple effectors act to modulate Okazaki fragment size.

1992 • 194 citations

Size classes of products synthesized processively by DNA polymerase III and DNA polymerase III holoenzyme of Escherichia coli.

1981 • 186 citations

Purification and characterization of DNA polymerase III'. Identification of tau as a subunit of the DNA polymerase III holoenzyme.

1982 • 176 citations

DNA Polymerase III holoenzyme of Escherichia coli. IV. The holoenzyme is an asymmetric dimer with twin active sites.

1988 • 168 citations

Homology in accessory proteins of replicative polymerases—E.colito humans

1993 • 167 citations

A Transcriptional Enhancer Whose Function Imposes a Requirement That Proteins Track Along DNA

1992 • 130 citations

Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins.

1992 • 126 citations

Accessory proteins bind a primed template and mediate rapid cycling of DNA polymerase III holoenzyme from Escherichia coli.

1987 • 125 citations

DNA polymerase III holoenzyme of Escherichia coli. II. A novel complex including the gamma subunit essential for processive synthesis.

1988 • 116 citations

Constitution of the twin polymerase of DNA polymerase III holoenzyme.

1991 • 113 citations

DNA polymerase III accessory proteins. V. Theta encoded by holE

1993 • 106 citations

DNA polymerase III holoenzyme of Escherichia coli. III. Distinctive processive polymerases reconstituted from purified subunits.

1988 • 105 citations

Coordination of leading and lagging strand DNA synthesis at the replication fork of bacteriophage T7

1994 • 95 citations

Bacteriophage fd gene II-protein. II. Specific cleavage and relaxation of supercoiled RF from filamentous phages.

1979 • 84 citations

Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. II. Frequency of primer synthesis and efficiency of primer utilization control Okazaki fragment size.

1992 • 76 citations

DNA polymerase III accessory proteins. I. holA and holB encoding delta and delta'

1993 • 70 citations

Dynamics of DNA polymerase III holoenzyme of Escherichia coli in replication of a multiprimed template.

1985 • 68 citations

Cryoelectron microscopic visualization of functional subassemblies of the bacteriophage T4 DNA replication complex

1992 • 65 citations

Escherichia coli DNA polymerase II is stimulated by DNA polymerase III holoenzyme auxiliary subunits

1991 • 62 citations

ATP activation of DNA polymerase III holoenzyme from Escherichia coli. II. Initiation complex: stoichiometry and reactivity.

1982 • 60 citations

DNA polymerase III accessory proteins. III. holC and holD encoding chi and psi

1993 • 60 citations

[32] Radiolabeling of proteins for biochemical studies

1995 • 54 citations

DNA footprinting studies of the complex formed by the T4 DNA polymerase holoenzyme at a primer-template junction.

1991 • 47 citations

The cycling of Escherichia coli DNA polymerase III holoenzyme in replication.

1983 • 46 citations

DNA polymerase ε: in search of a function

1992 • 40 citations

Interaction between the replication origin and the initiator protein of the filamentous phage f1

1987 • 38 citations

The sliding clamp of DNA polymerase III holoenzyme encircles DNA.

1992 • 38 citations