A Critical Role for Conserved Residues in the Cleft of HLA-A2 in Presentation of a Nonapeptide to T Cells

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

1991 • 2,447 citations

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 Å resolution

1991 • 1,079 citations

Hydrogen bonding and biological specificity analysed by protein engineering

1985 • 1,050 citations

Crystal Structures of Two Viral Peptides in Complex with Murine MHC Class I H-2K ^b

1992 • 864 citations

Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells

1990 • 775 citations

Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule

1990 • 689 citations

The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

1991 • 687 citations

The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC

1992 • 670 citations

Specificity pockets for the side chains of peptide antigens in HLA-Aw68

1989 • 664 citations

The minimum peptide epitope from the influenza virus matrix protein. Extra and intracellular loading of HLA-A2.

1991 • 214 citations

The binding affinity and dissociation rates of peptides for class I major histocompatibility complex molecules

1991 • 187 citations

Effect of mutations and variations of HLA-A2 on recognition of a virus peptide epitope by cytotoxic T lymphocytes.

1988 • 117 citations

Identification of the nonamer peptide from influenza A matrix protein and the role of pockets of HLA‐A2 in its recognition by cytotoxic T lymphocytes

1992 • 114 citations

Comparison between two peptide epitopes presented to cytotoxic T lymphocytes by HLA-A2. Evidence for discrete locations within HLA-A2.

1989 • 54 citations

Class I cross-restricted T cells reveal low responder allele due to processing of viral antigen

1989 • 46 citations

Alloreactivity studied with mutants of HLA-A2.

1989 • 43 citations

Positioning of a peptide in the cleft of HLA-A2 by complementing amino acid changes.

1991 • 33 citations

Beastly behaviour

1987 • 2 citations