A DNA double-strand break repair-deficient mutant of CHO cells shows reduced radiosensitization after exposure to hyperthermic temperatures in the plateau phase of growth

Radiation Biology in Cancer Research

1980 • 782 citations

Hyperthermic Oncology 1984

1985 • 528 citations

Hyperthermia and Cancer

1982 • 474 citations

Hyperthermia and Cancer

1983 • 426 citations

X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining

1984 • 379 citations

X-ray-sensitive mutants of Chinese hamster ovary cell line isolation and cross-sensitivity to other DNA-damaging agents

1983 • 345 citations

Enzymatic Restriction of Mammalian Cell DNA Using Pvu II and Bam H1: Evidence for the Double-strand Break Origin of Chromosomal Aberrations

1984 • 313 citations

Molecular mechanisms involved in the production of chromosomal aberrations

1984 • 303 citations

Plateau-phase cultures of mammalian cells: an in vitro model for human cancer.

1972 • 226 citations

The Repair of Double-Strand DNA Breaks Correlates with Radiosensitivity of L5178Y-S and L5178Y-R Cells

1987 • 177 citations

Computer Programs for the Analysis of Cellular Survival Data

1987 • 171 citations

Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell

1983 • 170 citations

Hyperthermic Effects on DNA Repair Mechanisms

1977 • 168 citations

Heat-induced Lethality and Chromosomal Damage in Synchronized Chinese Hamster Cells Treated with 5-bromodeoxyuridine

1971 • 159 citations

Hyperthermic Radiosensitization of Synchronous Chinese Hamster Cells: Relationship between Lethality and Chromosomal Aberrations

1978 • 158 citations

The Effects of Hyperthermia on the Protein-to-DNA Ratio of Isolated HeLa Cell Chromatin

1978 • 151 citations

Cell cycle-dependent repair of double-strand DNA breaks in a ?-ray-sensitive Chinese hamster cell

1985 • 150 citations

Effect of Hyperthermia on Nonhistone Proteins Isolated with DNA

1978 • 148 citations

Enzymatic Restriction of Mammalian Cell DNA: Evidence for Double-strand Breaks as Potentially Lethal Lesions

1985 • 146 citations

National Cancer Institute Monographs

1961 • 140 citations

Effect of Hyperthermia on CHO DNA Polymerases α and β

1982 • 139 citations

Interaction of heat with radiation and chemotherapy.

1984 • 111 citations

Current Topics in Radiation Research

1971 • 106 citations

Effects of Hyperthermia on Repair of Radiation-Induced DNA Strand Breaks

1981 • 98 citations

Deficiency in DNA repair in mouse lymphoma strain L5178Y-S.

1987 • 96 citations

Double-strand break repair and G2 block in Chinese hamster ovary cells and their radiosensitive mutants

1985 • 94 citations

Excision of X-Ray-Induced Thymine Damage in Chromatin from Heated Cells

1979 • 89 citations

Characterization of an X-ray-hypersensitive mutant of V79 Chinese hamster cells

1988 • 83 citations

Inhibition of Repair of Radiation-induced Strand Breaks by Hyperthermia, and Its Relationship to Cell Survival after Hyperthermia Alone

1983 • 76 citations

Heat Shock (45°C) Results in an Increase of Nuclear Matrix Protein Mass in HeLa Cells

1986 • 75 citations

Radiosensitivity Throughout the Cell Cycle and Repair of Potentially Lethal Damage and DNA Double-strand Breaks in an X-ray-sensitive CHO Mutant

1990 • 72 citations

Variation through the Cell Cycle in the Dose-response of DNA Neutral Filter Elution in X-irradiated Synchronous CHO-cells

1988 • 71 citations

Hyperthermic Killing and Hyperthermic Radiosensitization in Chinese Hamster Ovary Cells: Effects of pH and Thermal Tolerance

1984 • 69 citations

Recovery of CHO Cells from Hyperthermic Potentiation to X Rays: Repair of DNA and Chromatin

1981 • 66 citations

Heat-induced Alterations in DNA Polymerase Activity of HeLa Cells and of Isolated Nuclei. Relation to Cell Survival

1985 • 63 citations

Hyperthermic Potentiation of Unrejoined DNA Strand Breaks Following Irradiation

1983 • 60 citations

Production and Repair of Chromosome Damage in an X-ray Sensitive CHO Mutant Visualized and Analysed in Interphase Using the Technique of Premature Chromosome Condensation

1990 • 59 citations

Effects of Hyperthermia on the Repair of X-ray-induced DNA Double Strand Breaks in Mouse L Cells

1983 • 58 citations

Radiosensitive Xrs-5 and Parental CHO Cells Show Identical DNA Neutral Filter Elution Dose—response: Implications for a Relationship between Cell Radiosensitivity and Induction of DNA Double-strand Breaks

1988 • 55 citations

Six complementation groups for ionising-radiation sensitivity in Chinese hamster cells

1988 • 55 citations

Hyperthermic Potentiation of the Effects of a Clinically Significant X-Ray Dose on Cell Survival, DNA Damage, and DNA Repair

1981 • 54 citations

¹²⁵IdUrd-induced Chromosome Fragments, Assayed by Premature Chromosome Condensation, and DNA Double-strand Breaks Have Similar Repair Kinetics in G₁-phase CHO-cells

1987 • 51 citations

Factors Affecting the Heat-Induced Increase in Protein Content of Chromatin

1980 • 50 citations

Effects of hyperthermia on the repair of radiation-induced DNA single-and double-strand breaks in DNA double-strand break repair-deficient and repair-proficient cell lines

1990 • 49 citations

Biphasic Survival Curves for XRS Radiosensitive Cells: Subpopulations or Transient Expression of Repair Competence?

1989 • 49 citations

Effect of Arabinofuranosyladenine on Radiation-Induced Chromosome Damage in Plateau-Phase CHO Cells Measured by Premature Chromosome Condensation: Implications for Repair and Fixation of α-PLD

1988 • 45 citations

Transient Thermal Tolerance: Cell Killing and Polymerase Activities

1982 • 45 citations

Alterations in the Nuclear Matrix Protein Mass Correlate with Heat-induced Inhibition of DNA Single-strand-break Repair

1987 • 40 citations

Nuclear Protein Following Heat Shock: Protein Removal Kinetics and Cell Cycle Rearrangements

1986 • 36 citations

Effect of glycerol and low pH on heat-induced cell killing and loss of cellular DNA polymerase activities in Chinese hamster ovary cells.

1984 • 32 citations

Inhibition of Repair of Radiation-induced DNA Damage by Thermal Shock in Chinese Hamster Ovary Cells

1987 • 29 citations

Effects of hyperthermia on chromatin condensation and nucleoli disintegration as visualized by induction of premature chromosome condensation in interphase mammalian cells.

1989 • 25 citations

Effect of Glycerol and Low pH on Heat-Induced Cell Killing and Loss of Cellular DNA Polymerase Activities in Chinese Hamster Ovary Cells

1984 • 23 citations

Differences in Heat-induced Cell Killing as Determined in Three Mammalian Cell Lines Do Not Correspond with the Extent of Heat Radiosensitization

1986 • 13 citations

Effects of hyperthermia on DNA polymerases alpha and beta: relationship to thermal cell killing and radiosensitization

1982 • 8 citations

Deleted Work

1955 • 0 citations