An immunohistochemical study of cathepsin E in Alzheimer-type dementia brains

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

1993 • 4,145 citations

Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration.

1993 • 575 citations

Neurofibrillary tangles of paired helical filaments

1976 • 366 citations

MOLECULAR BIOLOGY OF ALZHEIMER'S DISEASE

1989 • 266 citations

MHC class II‐positive microglia in human brain: Association with alzheimer lesions

1992 • 221 citations

Antigen processing for presentation by class II major histocompatibility complex requires cleavage by cathepsin E

1992 • 207 citations

Age-Related Changes in Activities and Localizations of Cathepsins D, E, B, and L in the Rat Brain Tissues

1994 • 169 citations

Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: evidence for a neuronal origin

1990 • 168 citations

Cleavage at the amino and carboxyl termini of Alzheimer's amyloid-beta by cathepsin D

1994 • 126 citations

Quantitation and immunohistochemical localization of cathepsins E and D in rat tissues and blood cells

1989 • 126 citations

Proteolytic processing of beta-amyloid precursor by calpain I

1990 • 105 citations

Transient Forebrain Ischemia Induces Increased Expression and Specific Localization of Cathepsins E and D in Rat Hippocampus and Neostriatum

1993 • 70 citations

Immunodetection of cathepsin D in neuritic plaques found in brains of patients with dementia of Alzheimer type.

1989 • 53 citations

Rabbit procathepsin E and cathepsin E

1993 • 45 citations

Antigenic expression of cathepsin B in aged human brain

1990 • 43 citations

Amyloidosis in aging and Alzheimer's disease.

1992 • 32 citations

Two‐way cleavage of β‐amyloid protein precursor by multicatalytic proteinase

1992 • 27 citations

Changes of mitochondrial glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase during brain development

1965 • 26 citations

Leupeptin as a tool for the detection of the sites of catabolism of rat high-density lipoprotein apolipoproteins A-I and E

1985 • 19 citations

Kinetic parameters for the generation of endothelins-1,-2 and -3 by human cathepsin E

1992 • 7 citations

Isolation and some properties of a cathepsin E type proteinase from rat spleen.

1989 • 3 citations

Differential therapeutic responses of thiol compounds in the reversal of methylmercury inhibited acid phosphatase and cathepsin E in the central nervous system of rat

1992 • 3 citations