Lactic acid bacteria differ in their ability to induce functional regulatory T cells in humans

Hay fever, hygiene, and household size.

1989 • 4,910 citations

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

2001 • 3,260 citations

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2002 • 2,592 citations

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

2006 • 2,516 citations

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2001 • 2,461 citations

A microbial symbiosis factor prevents intestinal inflammatory disease

2008 • 2,187 citations

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

2006 • 1,496 citations

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

2003 • 1,252 citations

JM2, encoding a fork head–related protein, is mutated in X-linked autoimmunity–allergic disregulation syndrome

2000 • 909 citations

Selective probiotic bacteria induce IL-10–producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell–specific intercellular adhesion molecule 3–grabbing nonintegrin

2005 • 743 citations

Induction of FOXP3 expression in naive human CD4+FOXP3− T cells by T-cell receptor stimulation is transforming growth factor-β–dependent but does not confer a regulatory phenotype

2007 • 730 citations

High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota

2008 • 639 citations

Probiotic supplementation for the first 6 months of life fails to reduce the risk of atopic dermatitis and increases the risk of allergen sensitization in high-risk children: A randomized controlled trial

2007 • 536 citations

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Transient regulatory T-cells: A state attained by all activated human T-cells

2006 • 336 citations

Probiotic‐induced suppression of allergic sensitization and airway inflammation is associated with an increase of T regulatory‐dependent mechanisms in a murine model of asthma

2006 • 330 citations

Improved multiplex immunoassay performance in human plasma and synovial fluid following removal of interfering heterophilic antibodies

2005 • 254 citations

Identification of strong interleukin‐10 inducing lactic acid bacteria which down‐regulate T helper type 2 cytokines

2005 • 225 citations

Effects of probiotic therapy on the activity and activation of mild rheumatoid arthritis – a pilot study

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Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant mice

2005 • 217 citations

Lactobacillus GG Bacteria Ameliorate Arthritis in Lewis Rats

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The IL-17 cytokine family and their role in allergic inflammation

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Early markers of allergic disease in a primary prevention study using probiotics: 2.5‐year follow‐up phase

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Strain-dependent effects of probiotic lactobacilli on EAE autoimmunity

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Probiotics in primary prevention of atopic disease

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The role of T regulatory cells in asthma

2005 • 55 citations