Transplanting oligodendrocyte progenitors into the adult CNS

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

1983 • 2,009 citations

Cell death and control of cell survival in the oligodendrocyte lineage

1992 • 1,331 citations

The oligodendrocyte and its many cellular processes

1993 • 837 citations

Multiple extracellular signals are required for long-term oligodendrocyte survival

1993 • 707 citations

Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells.

1990 • 573 citations

Evidence for migration of oligodendrocyte–type-2 astrocyte progenitor cells into the developing rat optic nerve

1987 • 471 citations

Repair of demyelinated lesions by transplantation of purified 0-2A progenitor cells

1993 • 441 citations

A crucial role for neurotrophin-3 in oligodendrocyte development

1994 • 353 citations

Type 1 astrocytes and oligodendrocyte‐type 2 astrocyte glial progenitors migrate toward distinct molecules

1990 • 286 citations

The migrational patterns and developmental fates of glial precursors in the rat subventricular zone are temporally regulated

1993 • 273 citations

Differential myelinogenic capacity of specific developmental stages of the oligodendrocyte lineage upon transplantation into hypomyelinating hosts

1993 • 259 citations

Insulin-like growth factor I gene expression is induced in astrocytes during experimental demyelination.

1992 • 223 citations

Radiation-induced astrocytic and microglial responses in mouse brain

1993 • 184 citations

Visualization of O-2A progenitor cells in developing and adult rat optic nerve by quisqualate-stimulated cobalt uptake

1992 • 178 citations

Transplantation of oligodendrocytes and Schwann cells into the spinal cord of the myelin-deficient rat

1988 • 170 citations

Remyelination of mouse spinal cord axons demyelinated by local injection of lysolecithin

1995 • 165 citations

Transplanted CG4 Cells (an Oligodendrocyte Progenitor Cell Line) Survive, Migrate, and Contribute to Repair of Areas of Demyelination in X-Irradiated and Damaged Spinal Cord but Not in Normal Spinal Cord

1996 • 146 citations

O2A progenitor cells transplanted into the neonatal rat brain develop into oligodendrocytes but not astrocytes.

1993 • 142 citations

Transplantation of an oligodendrocyte cell line leading to extensive myelination.

1994 • 135 citations

Gliogenesis in rat optic nerve: Astrocytes are generated in a single wave before oligodendrocytes

1990 • 133 citations

Transplanted type-1 astrocytes facilitate repair of demyelinating lesions by host oligodendrocytes in adult rat spinal cord

1991 • 133 citations

Survival and differentiation of oligodendrocytes from neural tissue transplanted into new-born mouse brain

1983 • 132 citations

A point mutation in the proteolipid protein gene of the ‘shaking pup’ interrupts oligodendrocyte development

1990 • 115 citations

The taiep rat: A myelin mutant with an associated oligodendrocyte microtubular defect

1992 • 114 citations

Glial-cell transplantation and plasticity in the O-2A lineage — implications for CNS repair

1995 • 112 citations

Transplantation of glial cells into the CNS

1991 • 107 citations

Functional Capacities of Transplanted Cell-Sorted Adult Oligodendrocytes

1992 • 104 citations

Differentiation of the O‐2A progenitor cell line CG‐4 into oligodendrocytes and astrocytes following transplantation into glia‐deficient areas of CNS white matter

1995 • 103 citations

Tracing transplanted oligodendrocytes during migration and maturation in the shiverer mouse brain

1991 • 72 citations

Remyelination by transplanted oligodendrocytes of a demyelinated lesion in the spinal cord of the adult shiverer mouse

1988 • 71 citations

Myelin formation following transplantation of normal fetal glia into myelin-deficient rat spinal cord

1990 • 65 citations

Glial cell transplanatation and remyelination of the central nervous system

1996 • 65 citations

Transplantation of oligodendrocyte precursors in the adult demyelinated spinal cord: Migration and remyelination

1993 • 65 citations

In vitro and In vivo Analysis of a Rat Bipotential O – 2A Progenitor Cell Line Containing the Temperature‐sensitive Mutant Gene of the SV40 Large T Antigen

1993 • 64 citations

Lines of glial precursor cells immortalised with a temperature‐sensitive oncogene give rise to astrocytes and oligodendrocytes following transplantation into demyelinated lesions in the central nervous system

1993 • 61 citations

Cell-cell interactions during the migration of myelin-forming cells transplanted in the demyelinated spinal cord

1996 • 61 citations

Myelination and Remyelination in the Central Nervous System by Transplanted Oligodendrocytes Using the Shiverer Model

1989 • 60 citations

Possible association of platelet-derived growth factor (PDGF) with the appearance of reactive astrocytes following brain injury in situ

1986 • 58 citations

Transplanted Transgenically Marked Oligodendrocytes Survive, Migrate and Myelinate in the Normal Mouse Brain as They Do in the Shiverer Mouse Brain

1994 • 52 citations

Transplantation of oligodendrocytes in the newborn mouse brain: extension of myelination by transplanted cells. Anatomical study

1987 • 50 citations

Oligodendrocyte precursor (O-2A progenitor cell) migration; a model system for the study of cell migration in the developing central nervous system

1993 • 49 citations

Comparative migration and development of astroglial and oligodendroglial cell populations from a brain xenograft

1992 • 37 citations

Myelination by mature ovine oligodendrocytes in vivo and in vitro: Evidence that different steps in the myelination process are independently controlled

1993 • 26 citations

Myelination of the rat retina by transplantation of oligodendrocytes into 4-day-old hosts

1991 • 25 citations

Directed migration of transplanted glial cells toward a spinal cord demyelinating lesion

1993 • 20 citations

Acute dispersion of glial cells following transplantation into the myelin‐deficient rat spinal cord

1995 • 16 citations

Restricted Migration of Transplanted Oligodendrocytes or theirProgenitors, Revealed by Transgenic Marker MβP

1993 • 14 citations