Back to search

Neutrophil Elastase Inhibitor, ONO-5046, Modulates Acid-induced Lung and Systemic Injury in Rabbits

Data up to Jan 2025

Published1997
Citations25
References21

Total Citations Per Year

Abstract

References (21)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Two-step model of leukocyte-endothelial cell interaction in inflammation: distinct roles for LECAM-1 and the leukocyte beta 2 integrins in vivo.

1991 • 977 citations

Aspiration during anaesthesia: a computer‐aided study of 185 358 anaesthetics

1986 • 525 citations

Identification of patients with acute lung injury. Predictors of mortality.

1995 • 502 citations

CD18-dependent and -independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits.

1990 • 423 citations

Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits

1985 • 369 citations

ONO-5046, a novel inhibitor of human neutrophil elastase

1991 • 359 citations

The Role of Neutrophils, Oxidants, and Proteases in the Pathogenesis of Acid Pulmonary Injury

1992 • 133 citations

Roles of neutrophil elastase and superoxide anion in leukotriene B4-induced lung injury in rabbit

1994 • 120 citations

Adhesion Molecules Involved in the Microvascular Inflammatory Response

1992 • 104 citations

Effect of a specific neutrophil elastase inhibitor, ONO-5046, on endotoxin-induced acute lung injury.

1996 • 104 citations

Tumor Necrosis Factor-α Mediates Acid Aspiration-induced Systemic Organ Injury

1990 • 102 citations

Distribution volumes of [131I]albumin, [14C]sucrose, and 36Cl in sheep lung

1975 • 99 citations

Proteolytic inactivation of dog lung surfactant-associated proteins by neutrophil elastase

1989 • 91 citations

The Role of Phagocyte Proteinases and Proteinase Inhibitors in Multiple Organ Failure

1994 • 72 citations

Effects of ONO-5046, a specific neutrophil elastase inhibitor, on endotoxin-induced lung injury in sheep

1994 • 65 citations

Acid aspiration-induced acute lung injury causes leukocyte-dependent systemic organ injury

1993 • 61 citations

Synergism between leukotriene B4 and thromboxane A2 in mediating acid-aspiration injury.

1992 • 54 citations

The Effect of Pentoxifylline on Acid-induced Alveolar Epithelial Injury

1995 • 44 citations

Soluble Complement Receptor Type 1 Inhibited the Systemic Organ Injury Caused by Acid Instillation into a Lung

1996 • 36 citations

Soluble ICAM-1 (sICAM-1) Provokes PMN Elastase Release

1996 • 20 citations

Cited By (0)

Loading...
Neutrophil Elastase Inhibitor, ONO-5046, Modulates Acid-induced Lung and Systemic Injury… (1997) – Anesthesiology | Metascience Observatory Explorer