Comparative Effects of Valproate and the New Experimental Anticonvulsant Drug α‐Ethyl‐α‐Methyl‐Thiobutyrolactone on Selected Metabolite Levels in the Plasma, Livers, and Brains of Infant Mice

A Flexible System of Enzymatic Analysis

1972 • 4,133 citations

Effect of Ischemia on Known Substrates and Cofactors of the Glycolytic Pathway in Brain

1964 • 2,227 citations

A Note on a Simple Apparatus for Detecting Neurological Deficit in Rats and Mice**College of Pharmacy, University of Nebraska, Lincoln 8.

1957 • 1,671 citations

Enzymic determination of <scp>d</scp>(−)-β-hydroxybutyric acid and acetoacetic acid in blood

1962 • 1,407 citations

Valproic acid hepatic fatalities

1987 • 491 citations

Effects of Changes in Brain Metabolism on the Levels of Citric Acid Cycle Intermediates

1966 • 396 citations

EFFECTS OF DI‐n‐PROPYLACETATE, AN ANTICONVULSIVE COMPOUND, ON GABA METABOLISM¹

1969 • 394 citations

Effect of sodium n-dipropylacetate on audiogenic seizures and brain γ-aminobutyric acid level

1973 • 285 citations

Anticonvulsant action of ethanolamine-O-sulphate and di-n-propylacetate and the metabolism of γ-aminobutyric acid (GABA) in mice with audiogenic seizures

1976 • 175 citations

Influence of valproic acid on hepatic carbohydrate and lipid metabolism

1983 • 159 citations

DISTRIBUTION OF γ‐AMINOBUTYRIC ACID IN THE LAYERS OF THE CEREBRAL AND CEREBELLAR CORTEX. IMPLICATIONS FOR ITS PHYSIOLOGICAL ROLE*

1962 • 110 citations

Effect of n‐dipropylacetate on amino acid concentrations in mouse brain: correlations with anti‐convulsant activity

1978 • 108 citations

A COLLECTION OF METABOLITE ASSAYS

1972 • 71 citations

[72] Assay of coenzyme A and some acyl derivatives

1969 • 63 citations

Differential effects of n‐dipropylacetate and amino‐oxyacetic acid on Gm‐aminobutyric acid levels in discrete areas of rat brain¹

1979 • 61 citations

A single therapeutic dose of valproate affects liver carbohydrate, fat, adenylate, amino acid, coenzyme A, and carnitine metabolism in infant mice: Possible clinical significance

1985 • 58 citations

CoA cycling: An enzymatic amplification method for determination of CoASH and acetyl CoA

1975 • 56 citations

QUANTITATIVE METHODS FOR MEASURING THE HISTOCHEMICAL DISTRIBUTION OF ALANINE, GLUTAMATE AND GLUTAMINE IN BRAIN*

1966 • 54 citations

Chronic valproate administration reduces fasting ketonemia in children

1983 • 39 citations

Chronic valproate administration produces hepatic dysfunction and may delay brain maturation in infant mice

1981 • 39 citations

Physiological regulation of the picrotoxin receptor by gamma- butyrolactones and gamma-thiobutyrolactones in cultured hippocampal neurons

1990 • 34 citations

Alkyl-substituted thiolo-, thiono-, and dithio-.gamma.-butyrolactones: new classes of convulsant and anticonvulsant agents

1986 • 31 citations

Binding interactions of convulsant and anticonvulsant gamma-butyrolactones and gamma-thiobutyrolactones with the picrotoxin receptor.

1990 • 28 citations

A spectrophotometric cycling assay for reduced coenzyme a and its esters in small amounts of tissue

1979 • 26 citations

Comparison of the Anticonvulsant Activities of Ethosuximide, Valproate, and a New Anticonvulsant, Thiobutyrolactone

1989 • 25 citations