Octamer independent activation of transcription from the kappa immunoglobulin germline promoter

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Establishment and Characterization of BALB/c Lymphoma Lines with B Cell Properties

1979 • 677 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence.

1984 • 564 citations

Regulation of Genome Rearrangement Events during Lymphocyte Differentiation

1986 • 422 citations

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

1987 • 398 citations

Transcription cell type specificity is conferred by an immunoglobulin VH gene promoter that includes a functional consensus sequence

1985 • 313 citations

Recombination between immunoglobulin variable region gene segments is enhanced by transcription

1986 • 308 citations

Immunoglobulin Gene Transcription

1991 • 294 citations

Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival.

1993 • 265 citations

Two regulatory elements for immunoglobulin kappa light chain gene expression.

1984 • 197 citations

Transcription of the unrearranged mouse Cκ locus: Sequence of the initiation region and comparison of activity with a rearranged Vκ-Cκ gene

1981 • 190 citations

OBP100 binds remarkably degenerate octamer motifs through specific interactions with flanking sequences.

1988 • 184 citations

Multiple DNA sequence elements are necessary for the function of an immunoglobulin heavy chain promoter.

1987 • 123 citations

Functional characterization of the developmentally controlled immunoglobulin kappa 3' enhancer: regulation by Id, a repressor of helix-loop-helix transcription factors.

1991 • 123 citations

Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of immunoglobulin promoters.

1990 • 117 citations

A microtransfection method using the luciferase-encoding reporter gene for the assay of human immunodeficiency virus LTR promoter activity

1990 • 104 citations

The importance of the 3′-enhancer region in immunoglobulinxgene expression

1990 • 83 citations

Cell type- and stage-specific expression of the CD20/B1 antigen correlates with the activity of a diverged octamer DNA motif present in its promoter.

1993 • 61 citations

Initiation and processing of two kappa immunoglobulin germ line transcripts in mouse B cells.

1990 • 59 citations

The 3′ enhancer region determines the B/T specificity and pro-B/pre-B specificity of immunoglobulin Vκ-Jκ joining

1995 • 59 citations

A novel upstream element compensates for an ineffectual octamer motif in an immunoglobulin V kappa promoter.

1990 • 50 citations

Rearrangement and expression of rabbit immunoglobulin kappa light chain gene in transgenic mice.

1987 • 49 citations

Tissue Specificity of the Initiation of Immunoglobulin κ<i />Gene Transcription

1984 • 49 citations

Tandem kappa immunoglobulin promoters are equally active in the presence of the kappa enhancer: Implications for models of enhancer function

1986 • 47 citations

Activation of Octamer-Containing Promoters by Either Octamer-Binding Transcription Factor 1 (OTF-1) or OTF-2 and Requirement of an Additional B-Cell-Specific Component for Optimal Transcription of Immunoglobulin Promoters

1990 • 41 citations

Functional Characterization of the Developmentally Controlled Immunoglobulin Kappa 3′ Enhancer: Regulation by Id, a Repressor of Helix-Loop-Helix Transcription Factors

1991 • 40 citations

Kappa immunoglobulin promoters and enhancers display developmentally controlled interactions

1993 • 38 citations

Luminescent reporter gene assays for luciferase and beta-galactosidase using a liquid scintillation counter.

1993 • 36 citations

Identification of a second inducible DNA-protein interaction in the kappa immunoglobulin enhancer

1990 • 35 citations

Identification of an octamer-binding site in the mouse kappa light-chain immunoglobulin enhancer.

1989 • 35 citations

Selective synergy of immunoglobulin enhancer elements in B-cell development: a characteristic of kappa light chain enhancers, but not heavy chain enhancers

1994 • 32 citations

Constitutively expressed Oct-2 prevents immunoglobulin gene silencing in myeloma × T cell hybrids

1994 • 31 citations

Immunoglobulin x light chain germ‐line transcripts in human precursor B lymphocytes

1992 • 21 citations

Initiation and Processing of Two Kappa Immunoglobulin Germ Line Transcripts in Mouse B Cells

1990 • 21 citations

Identification of an octamer-binding site in the human kappa light-chain enhancer.

1990 • 16 citations

Identification of an Octamer-Binding Site in the Mouse Kappa Light-Chain Immunoglobulin Enhancer

1989 • 15 citations

Identification of a germ line transcript from the unrearranged kappa gene in human B cells.

1989 • 12 citations

Identification of an Octamer-Binding Site in the Human Kappa Light-Chain Enhancer

1990 • 9 citations

Identification of a Germ Line Transcript from the Unrearranged Kappa Gene in Human B Cells

1989 • 6 citations