6-Hydroxydopamine, noradrenergic reward, and schizophrenia.

Schizotaxia, schizotypy, schizophrenia.

1962 • 1,985 citations

6-hydroxy-dopamine induced degeneration of central monoamine neurons

1968 • 1,419 citations

Basic Mechanisms of the Epilepsies.

1970 • 1,131 citations

EFFECTS OF 6‐HYDROXYDOPAMINE ON CATECHOLAMINE CONTAINING NEURONES IN THE RAT BRAIN

1970 • 653 citations

A rapid, simplified procedure for simultaneous assay of norepinephrine, dopamine, and 5-hydroxytryptamine from discrete brain areas

1971 • 551 citations

Depletion of brain noradrenaline and dopamine by 6‐hydroxydopamine

1971 • 535 citations

Possible Etiology of Schizophrenia: Progressive Damage to the Noradrenergic Reward System by 6-Hydroxydopamine

1971 • 480 citations

Hypothalamic Substrates of Reward

1962 • 474 citations

Lesions of Central Norepinephrine Terminals with 6-OH-Dopamine: Biochemistry and Fine Structure

1969 • 421 citations

Supersensitivity and subsensitivity to sympathomimetic amines.

1963 • 412 citations

Der L-Dioxyphenylalanin (=L-DOPA)-Effekt beim Parkinson-Syndrom des Menschen: Zur Pathogenese und Behandlung der Parkinson-Akinese

1962 • 248 citations

Release of norepinephrine from hypothalamus and amygdala by rewarding medial forebrain bundle stimulation and amphetamine.

1969 • 227 citations

Biochemical Theories of Schizophrenia

1959 • 222 citations

Concentrations of 5-hydroxyindolylacetic acid and homovanillic acid in the cerebrospinal fluid of the dog before and during treatment with probenecid

1966 • 189 citations

Facilitation of Brain Self-Stimulation by Central Administration of Norepinephrine

1969 • 158 citations

5-hydroxyindoleacetic and homovanillic acid levels in the cerebrospinal fluid of healthy volunteers and patients with Parkinson's syndrome

1967 • 126 citations

Intracranial reward and the forebrain's serotonergic mechanism: Studies employing para-chlorophenylalanine and para-chloroamphetamine

1971 • 108 citations

Intracranial Self-Stimulation and Wakefulness: Effect of Manipulating Ambient Brain Catecholamines

1970 • 104 citations

Central catecholamine turnover and self-stimulation behaviour

1971 • 91 citations

Monoamines et système nerveux central

1962 • 87 citations

Effect of 6-Hydroxydopamine on behaviour and cerebral amine content in rats

1969 • 73 citations

Theories of Biological Etiology of Affective Disorders

1970 • 68 citations

The effect of L-Dopa on monoamine metabolites in Parkinson's disease

1970 • 64 citations

Deficient transport mechanism for the removal of acid monoamine metabolites from cerebrospinal fluid

1969 • 57 citations

The Pharmacology of Psychotherapeutic Drugs

1969 • 19 citations

Molecular Theory of Odour

1968 • 10 citations