Random mutant generation and its utility in uncovering structural and functional features of cytochromeb inSaccharomyces cerevisiae

The molecular biology of the yeast saccharomyces: Life cycle and inheritance

1982 • 1,361 citations

Possible molecular mechanisms of the protonmotive function of cytochrome systems

1976 • 1,252 citations

The Molecular biology of the yeast saccharomyces, life cycle and inheritance

1981 • 636 citations

Sequence of introns and flanking exons in wild-type and box3 mutants of cytochrome b reveals an interlaced splicing protein coded by an intron

1980 • 477 citations

Sequence homology and structural similarity between cytochrome b of mitochondrial complex III and the chloroplast b6-f complex: position of the cytochrome b hemes in the membrane.

1984 • 398 citations

Assembly of the mitochondrial membrane system. DNA sequence and organization of the cytochrome b gene in Saccharomyces cerevisiae D273-10B.

1980 • 375 citations

Electron and proton transfers through quinones and cytochrome bc complexes

1984 • 344 citations

[24] Use of specific inhibitors on the mitochondrial bc1 complex

1986 • 333 citations

The action of some derivatives of phenylurethan and of 3-phenyl-1,1-dimethylurea on the Hill reaction

1956 • 241 citations

Location of haem‐binding sites in the mitochondrial cytochrome b

1984 • 186 citations

Molecular basis for resistance to antimycin and diuron, Q-cycle inhibitors acting at the Qi site in the mitochondrial ubiquinol-cytochrome c reductase in Saccharomyces cerevisiae.

1988 • 175 citations

AMolecular Description of Biological Membrane Components by Computer Aided Conformational Analysis

2019 • 151 citations

Complete inhibition of electron transfer from ubiquinol to cytochrome b by the combined action of antimycin and myxothiazol

1981 • 149 citations

Mutational analysis of the mouse mitochondrial cytochrome b gene

1988 • 147 citations

Molecular Basis for Resistance to Myxothiazol, Mucidin (Strobilurin A), and Stigmatellin

1989 • 145 citations

Relationship between Certain Components of the Cytochrome System

1955 • 130 citations

Binding of HQNO to beef-heart sub-mitochondrial particles

1977 • 115 citations

Calculation of the three-dimensional structure of Saccharomyces cerevisiae cytochrome b inserted in a lipid matrix.

1988 • 109 citations

Mutations conferring resistance to quinol oxidation (Qz) inhibitors of the cyt bc1 complex of Rhodobacter capsulatus.

1989 • 101 citations

The mode of action of stigmatellin, a new inhibitor of the cytochrome b-c1 segment of the respiratory chain

1984 • 92 citations

Catalytic Sites for Reduction and Oxidation of Quinones

1987 • 80 citations

Stigmatellin. A dual type inhibitor of photosynthetic electron transport

1985 • 77 citations

Mucidin and strobilurin A are identical and inhibit electron transfer in the cytochrome bc1 complex of the mitochondrial respiratory chain at the same site as myxothiazol

1986 • 76 citations

DNA sequence analysis of diuron‐resistant mutations in the mitochondrial cytochrome b gene of Saccharomyces cerevisiae

1986 • 75 citations

Spatial Organization of the Redox Active Centers in the Bovine Heart Ubiquinol-cytochrome c Oxidoreductase

1989 • 71 citations

Point mutation in cytochrome b of yeast ubihydroquinone:cytochrome‐c oxidoreductase causing myxothiazol resistance and facilitated dissociation of the iron‐sulfur subunit

1992 • 66 citations

Intragenic suppressors reveal long distance interactions between inactivating and reactivating amino acid replacements generating three-dimensional constraints in the structure of mitochondrial cytochrome b.

1990 • 56 citations

Pseudo-wild type revertants from inactive apocytochrome b mutants as a tool for the analysis of the structure/function relationships of the mitochondrial ubiquinol-cytochrome c reductase of Saccharomyces cerevisiae.

1990 • 55 citations

Properties of 3‐(3,4‐Dichlorophenyl)‐1,1‐dimethylurea and Other Inhibitors of the Cytochromebc₁Segment of the Mitochondrial Respiratory Chain inSaccharomyces cerevisiae

1978 • 55 citations

Mucidin Resistance in Yeast. Isolation, Characterization and Genetic Analysis of Nuclear and Mitochondrial Mucidin-Resistant Mutants of Saccharomyces cerevisiae

1977 • 54 citations

Allelism studies of mitochondrial mutants resistant to antimycin A or funiculosin in Saccharomyces cerevisiae

1977 • 53 citations

Mitochondrial genetics of Chlamydomonas reinhardtii: resistance mutations marking the cytochrome b gene.

1991 • 50 citations

Two changes of the same nucleotide confer resistance to diuron and antimycin in the mitochondrial cytochrome b gene of Schizosaccharomyces pombe

1988 • 49 citations

Mitochondrial Heredity of Resistance to 3‐(3,4‐Dichlorophenyl)‐1,1‐dimethylurea, an Inhibitor of Cytochrome b Oxidation, in Saccharomyces cerevisiae

1977 • 49 citations

Genetic localization of diuron- and mucidin-resistant mutants relative to a group of loci of the mitochondrial DNA controlling coenzyme QH2-cytochrome c reductase in Saccharomyces cerevisiae

1979 • 49 citations

Mitochondrial and nuclear myxothiazol resistance in Saccharomyces cerevisiae

1982 • 48 citations

Structure/function relationships in mitochondrial cytochrome b revealed by the kinetic and circular dichroic properties of two yeast inhibitor‐resistant mutants

1991 • 48 citations

MOSAIC ORGANIZATION AND EXPRESSION OF THE MITOCHONDRIAL DNA REGION CONTROLLING CYTOCHROME c REDUCTASE AND OXIDASE

1978 • 47 citations

Isolation and RNA sequence analysis of cytochrome b mutants resistant to funiculosin, a center i inhibitor of the mitochondrial ubiquinol‐cytochrome c reductase in Saccharomyces cerevisiae

1990 • 39 citations

Assembly of the mitochondrial membrane system

1980 • 38 citations

Cytoplasmic inheritance of antimycin A resistance in Saccharomyces cerevisiae

1976 • 32 citations

Antimycin resistance in saccharomyces cerevisiae: a new mutation on the mitDNA conferring antimycin resistance on the mitchondrial respiratory chain

1976 • 31 citations

Inhibition of electron transport of rat-liver mitochondria by synthesized antimycin A analogs

1993 • 26 citations

Allelism relationships between diuron-resistant, antimycin-resistant and funiculosin-resistant loci of the mitochondrial map in Saccharomyces cerevisiae

1979 • 26 citations

Genetic screening in Saccharomyces cerevisiae for large numbers of mitochondrial point mutations which affect structure and function of catalytic subunits of cytochrome-c oxidase

1993 • 26 citations

Rapid screening of cytochromes of respiratory mutants of Saccharomyces cerevisiae

1993 • 26 citations

Mucidin‐resistant antimycin A‐sensitive mitochondrial mutant of Saccharomyces cerevisiae

1975 • 24 citations

Funiculosin: An antibiotic with antimycin-like inhibitory properties

1977 • 23 citations

Modification of the Spectral Properties of Cytochrome b in Mutants of Saccharomyces cerevisiae Resistant to 3‐(3,4‐Dichlorophenyl)‐1,1‐dimethylurea

1981 • 22 citations

Two substitutions at the same position in the mitochondrial cytochrome b gene of S. cerevisiae induce a mitochondrial myxothiazol resistance and impair the respiratory growth of the mutated strains abbeit maintaining a good electron transfer activity

1990 • 21 citations

Localization of mucidin-resistant locus muc3 on mitochondrial DNA with respect to ubiquinol-cytochrome c reductase deficient box loci. Locus muc3 is allelic to box2

1980 • 20 citations

Molecular analysis of revertants from a respiratory‐deficient mutant affecting the center o domain of cytochrome b in Saccharomyces cerevisiae

1991 • 15 citations

Mitochondrial cytochrome b genes with a six‐nucleotide deletion or single‐nucleotide substitutions confer resistance to antimycin A in the yeast Kluyveromyces lactis

1989 • 15 citations

3-(p-CHLOROPHENYL)-1, 1-DIMETHYLUREA AS A SPECIFIC INHIBITOR OF YEAST RESPIRATION

1966 • 10 citations

Effects of the Photosynthetic Inhibitors on the Respiration of Yeast Mitochondria

1968 • 9 citations

Structure-function relationships of cytochrome b by the genetic approach: Intragenic revertants derived from frameshift mutations in theSaccharomyces cerevisiae apocytochrome b gene

1992 • 8 citations

Inhibition of Respiration of Yeast by Photosynthesis Inhibiting Herbicides

1967 • 7 citations

Sequence Analysis of Mammalian Cytochrome b Mutants

1987 • 5 citations

Mapping of Drug-resistant Loci in the Coenzyme QH2: Cytochrome c Reductase Region of the Mitochondrial DNA Map in Saccharomyces cerevisiae

1977 • 5 citations

Interactions of the myxothiazol and mucidin toxophores with cytochrome b

1993 • 1 citations

The relationship between structure and activity of the methoxyacrylate toxophore

1993 • 1 citations