P-Selectin and P-Selectin Glycoprotein Ligand 1 Are Major Determinants for Th1 Cell Recruitment to Nonlymphoid Effector Sites in the Intestinal Lamina Propria

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

1996 • 1,227 citations

P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues

1997 • 735 citations

The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis

1996 • 723 citations

Chemokines and the Tissue-Specific Migration of Lymphocytes

2002 • 692 citations

Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo.

1994 • 625 citations

Critical role for β7 integrins in formation of the gut-associated lymphoid tissue

1996 • 558 citations

Interleukin‐12 is required for interferon‐γ production and lethality in lipopolysaccharide‐induced shock in mice

1995 • 491 citations

Rapid Acquisition of Tissue-specific Homing Phenotypes by CD4+ T Cells Activated in Cutaneous or Mucosal Lymphoid Tissues

2002 • 490 citations

Leukocyte-endothelial cell interactions: Molecular mechanisms and implications in gastrointestinal disease☆☆☆

1998 • 382 citations

Heterogeneity of Expression of E- and P-Selectins In Vivo

1996 • 312 citations

P-selectin glycoprotein ligand-1–deficient mice have impaired leukocyte tethering to E-selectin under flow

2002 • 241 citations

The Role of β7 Integrins in CD8 T Cell Trafficking During an Antiviral Immune Response

1999 • 211 citations

P-selectin glycoprotein ligand-1–deficient mice have impaired leukocyte tethering to E-selectin under flow

2002 • 196 citations

Migration and Function of Antigen-Primed Nonpolarized T Lymphocytes in Vivo

2001 • 176 citations

Interleukin 12 and Interleukin 4 Control T Cell Adhesion to Endothelial Selectins through Opposite Effects on α1,3-fucosyltransferase VII Gene Expression

1998 • 173 citations

CD4+ T Cells Migrate into Inflamed Skin Only If They Express Ligands for E- and P-Selectin

1998 • 169 citations

P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is a Physiological Ligand for E-Selectin in Mediating T Helper 1 Lymphocyte Migration

2000 • 162 citations

Interleukin-12 production by human monocytes infected with Mycobacterium tuberculosis: role of phagocytosis

1996 • 159 citations

Acquisition of Selectin Binding and Peripheral Homing Properties by CD4+ and CD8+ T Cells

1999 • 143 citations

Expression of Functional Selectin Ligands on Th Cells Is Differentially Regulated by IL-12 and IL-4

1999 • 140 citations

The roles of L-selectin, beta 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches.

1998 • 99 citations

Colitis Induced by Enteric Bacterial Antigen-Specific CD4+ T Cells Requires CD40-CD40 Ligand Interactions for a Sustained Increase in Mucosal IL-12

2000 • 94 citations

Alpha(1,3)-fucosyltransferase VII and alpha(2,3)-sialyltransferase IV are up-regulated in activated CD4 T cells and maintained after their differentiation into Th1 and migration into inflammatory sites.

1999 • 88 citations

The Roles of L-Selectin, β7 Integrins, and P-Selectin in Leukocyte Rolling and Adhesion in High Endothelial Venules of Peyer’s Patches

1998 • 78 citations

α(1,3)-Fucosyltransferase VII and α(2,3)-Sialyltransferase IV Are Up-Regulated in Activated CD4 T Cells and Maintained After Their Differentiation into Th1 and Migration into Inflammatory Sites

1999 • 71 citations

Characterization of a Novel Adhesion Function Blocking Monoclonal Antibody to Rat/Mouse P-Selectin Generated in the P-Selectin-Deficient Mouse

1997 • 67 citations

IL-12, STAT4-Dependent Up-Regulation of CD4+ T Cell Core 2 β-1,6-n-Acetylglucosaminyltransferase, an Enzyme Essential for Biosynthesis of P-Selectin Ligands

2001 • 66 citations

Cutting Edge: Differential Requirements for Stat4 in Expression of Glycosyltransferases Responsible for Selectin Ligand Formation in Th1 Cells

2001 • 66 citations

Differential Regulation of the IL-12 p40 Promoter and of p40 Secretion by CpG DNA and Lipopolysaccharide

1999 • 66 citations

β2 Integrins and ICAM-1 Are Involved in Establishment of the Intestinal Mucosal T Cell Compartment

1996 • 57 citations

The role of P-selectin in experimental colitis as determined by antibody immunoblockade and genetically deficient mice

2002 • 51 citations

Role of P‐selectin in radiation‐induced intestinal inflammatory damage

2001 • 41 citations

Differential role of E-selectin and P-selectin in T lymphocyte migration to cutaneous inflammatory reactions induced by cytokines

2002 • 36 citations

The Differentiated State of Intestinal Lamina Propria CD4+ T Cells Results in Altered Cytokine Production, Activation Threshold, and Costimulatory Requirements

1999 • 34 citations

Role of P-Selectin and Intercellular Adhesion Molecule-1 in TNB-Induced Colitis in Rats

2001 • 20 citations

Improved survival through the reduction of ischemia-reperfusion injury after rat intestinal transplantation using selective P-selectin blockade with P-selectin glycoprotein ligand-Ig

2002 • 19 citations