Structure of HLA Molecules and Immunosuppressive Effects of HLA Derived Peptides

The Fas Death Factor

1995 • 4,070 citations

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

Signal transduction by lymphocyte antigen receptors

1994 • 2,145 citations

MHC ligands and peptide motifs: first listing

1995 • 1,674 citations

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

1994 • 1,553 citations

MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

1994 • 1,448 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

T-Lymphocyte Recognition of Antigen in Association with Gene Products of the Major Histocompatibility Complex

1985 • 942 citations

Fundamental Immunology

1994 • 903 citations

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

1992 • 763 citations

Emerging Principles for the Recognition of Peptide Antigens by MHC Class I Molecules

1992 • 730 citations

Cyclosporin A, FK-506, and Rapamycin: Pharmacologic Probes of Lymphocyte Signal Transduction

1992 • 675 citations

Peptides Presented to the Immune System by the Murine Class II Major Histocompatibility Complex Molecule I-A _d

1992 • 654 citations

Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics

1992 • 531 citations

A binding site for the T-cell co-receptor CD8 on the α3 domain of HLA-A2

1990 • 527 citations

HLA-A2.1-Associated Peptides from a Mutant Cell Line: A Second Pathway of Antigen Presentation

1992 • 522 citations

The CTL's kiss of death

1995 • 504 citations

HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

1992 • 502 citations

Immunology: The ins and outs of antigen processing and presentations

1986 • 498 citations

Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle

1992 • 414 citations

Molecular Components of T-Cell Recognition

1992 • 304 citations

T-Lymphocyte-Antigen Interactions in Transplant Rejection

1990 • 257 citations

Polymorphism in the α3 domain of HLA-A molecules affects binding to CD8

1989 • 247 citations

Interaction of the Immunosuppressant Deoxyspergualin with a Member of the Hsp70 Family of Heat Shock Proteins

1992 • 232 citations

Structure of peptides associated with MHC class I molecules

1994 • 200 citations

Induction of immunity and oral tolerance with polymorphic class II major histocompatibility complex allopeptides in the rat.

1992 • 163 citations

Inhibition of alloreactive cytotoxic T lymphocytes by peptides from the α2 domain of HLA–A2

1987 • 146 citations

HLA-A2 peptides can regulate cytolysis by human allogeneic T lymphocytes

1987 • 132 citations

MECHANISMS OF ACQUIRED THYMIC UNRESPONSIVENESS TO RENAL ALLOGRAFTS

1994 • 129 citations

Exon shuffling in vivo can generate novel HLA class I molecules.

1985 • 121 citations

Peptide-induced conformational changes in class I heavy chains alter major histocompatibility complex recognition.

1992 • 118 citations

Major histocompatibility complex conformational epitopes are peptide specific.

1992 • 108 citations

An MHC interaction site maps to the amino-terminal half of the T cell receptor α chain variable domain

1992 • 100 citations

Induction of allograft tolerance in rats by an HLA class-I-derived peptide and cyclosporine A.

1994 • 97 citations

PROLONGATION OF ALLOGENEIC HEART GRAFT SURVIVAL IN RATS BY ADMINISTRATION OF A PEPTIDE (a.a. 75–84) FROM THE α1 HELIX OF THE FIRST DOMAIN OF HLA-B7 01

1995 • 67 citations

HLA-derived peptides which inhibit T cell function bind to members of the heat-shock protein 70 family.

1996 • 65 citations

PROLONGATION OF SKIN ALLOGRAFT SURVIVAL IN MICE FOLLOWING ADMINISTRATION OF ALLOTRAP1

1995 • 57 citations

In vitro mutagenesis at a single residue introduces B and T cell epitopes into a class I HLA molecule.

1987 • 57 citations

The binding of monoclonal antibodies to cell-surface molecules. A quantitative analysis with immunoglobulin G against two alloantigenic determinants of the human transplantation antigen HLA-A2

1983 • 56 citations

Peptides corresponding to the CD8 and CD4 binding domains of HLA molecules block T lymphocyte immune responses in vitro.

1994 • 38 citations

Transplantation biology

2015 • 29 citations

Determinants recognized by human cytotoxic T cells on a natural hybrid class I HLA molecule.

1985 • 29 citations

Peptide binding to the major histocompatibility complex molecules

1992 • 26 citations

HLA-Derived Peptides as Novel Immunotherapeutics

1995 • 22 citations

Novel immunotherapeutic strategies using MHC derived peptides.

1996 • 21 citations

Seeing double

1993 • 16 citations

The CD8 coreceptor interaction with the α3 domain of HLA class I is critical to the differentiation of human cytotoxic t-lymphocytes specific for HLA-A2 and HLA-Cw4

1993 • 15 citations