Angiotensin II receptors in endothelial cells

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Angiotensin II receptors and angiotensin II receptor antagonists.

1993 • 1,843 citations

Renin-angiotensin system: biochemistry and mechanisms of action.

1977 • 1,373 citations

Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor

1991 • 1,247 citations

The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells.

1995 • 918 citations

Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor

1995 • 858 citations

Identification of angiotensin II receptor subtypes

1989 • 825 citations

Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptor

1991 • 808 citations

Preliminary biochemical characterization of two angiotensin II receptor subtypes

1989 • 779 citations

Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors.

1993 • 767 citations

Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in mice

1995 • 740 citations

Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition.

1993 • 713 citations

Angiotensin II type 2 receptor mediates programmed cell death.

1996 • 707 citations

Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes.

1993 • 576 citations

Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells.

1989 • 558 citations

Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the renin-angiotensin system and thrombosis.

1995 • 539 citations

Phosphatidate accumulation in hormone-treated hepatocytes via a phospholipase D mechanism.

1987 • 472 citations

Phospholipase A2 and phospholipase C are activated by distinct GTP-binding proteins in response to alpha 1-adrenergic stimulation in FRTL5 thyroid cells.

1986 • 424 citations

Angiotensin II and Other Hypertrophic Stimuli Mediated by G Protein–Coupled Receptors Activate Tyrosine Kinase, Mitogen-Activated Protein Kinase, and 90-kD S6 Kinase in Cardiac Myocytes

1995 • 412 citations

Subclasses of angiotensin II binding sites and their functional significance.

1990 • 375 citations

Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells.

1992 • 358 citations

Angiotensin II Receptor Subtypes: Characterization, Signalling Mechanisms, and Possible Physiological Implications

1993 • 325 citations

Cardiac renin and angiotensins. Uptake from plasma versus in situ synthesis.

1994 • 309 citations

Angiotensin induction of PAI-1 expression in endothelial cells is mediated by the hexapeptide angiotensin IV.

1995 • 303 citations

Angiotensin II Stimulation of Prostaglandin Production in Cultured Human Vascular Endothelium

1975 • 278 citations

Angiotensin II induces plasminogen activator inhibitor-1 and -2 expression in vascular endothelial and smooth muscle cells.

1995 • 262 citations

Hormone and neurotransmitter receptors in an established vascular endothelial cell line.

1976 • 257 citations

Angiotensin II stimulation of rapid protein tyrosine phosphorylation and protein kinase activation in rat aortic smooth muscle cells.

1993 • 251 citations

Characterization of angiotensin II receptors in cultured adult rat cardiac fibroblasts. Coupling to signaling systems and gene expression.

1994 • 243 citations

Characterization of angiotensin II receptor subtypes in rat heart.

1992 • 236 citations

Proposed Update of Angiotensin Receptor Nomenclature

1995 • 220 citations

Biochemical Properties of the Ovarian Granulosa Cell Type 2-Angiotensin II Receptor*

1991 • 216 citations

The Angiotensin IV System: Functional Implications

1995 • 206 citations

Changes in expression of angiotensin receptor subtypes in the rat aorta during development

1991 • 203 citations

Endothelin, vasopressin, and angiotensin II enhance tyrosine phosphorylation by protein kinase C-dependent and -independent pathways in glomerular mesangial cells.

1991 • 195 citations

Discrimination of two angiotensin II receptor subtypes with a selective agonist analogue of angiotensin II, p-aminophenylalanine6 angiotensin II

1990 • 194 citations

Mitogen-activated Protein Kinases in Rat Brain Neuronal Cultures Are Activated by Angiotensin II Type 1 Receptors and Inhibited by Angiotensin II Type 2 Receptors

1996 • 191 citations

Metabolism and production of angiotensin I in different vascular beds in subjects with hypertension.

1990 • 191 citations

Tissue-specific expression of type 1 angiotensin II receptor subtypes. An in situ hybridization study.

1994 • 182 citations

Role of Ni in coupling angiotensin receptors to inhibition of adenylate cyclase in hepatocytes.

1985 • 175 citations

Production of angiotensin-(1-7) by human vascular endothelium.

1992 • 152 citations

Angiotensin receptor subtypes in rat, rabbit and monkey tissues: Relative distribution and species dependency

1991 • 142 citations

Use of Radioiodinated Fatty Acid for Photoscans of the Heart

1965 • 141 citations

Role of aminopeptidase activity in the regulation of the pressor activity of circulating angiotensins.

1990 • 129 citations

Distribution of angiotensin II receptor subtypes in rat and human kidney

1992 • 128 citations

Endothelial AT ₁ –Mediated Release of Nitric Oxide Decreases Angiotensin II Contractions in Rat Carotid Artery

1995 • 125 citations

A G Protein Is Involved in the Angiotensin AT2 Receptor Inhibition of the T-Type Calcium Current in Non-differentiated NG108-15 Cells

1995 • 124 citations

Angiotensin II stimulates the release of phospholipid-derived second messengers through multiple receptor subtypes in heart cells.

1994 • 124 citations

The Renin-Angiotensin System.

1981 • 123 citations

Identification and characterization of angiotensin II receptor subtypes in rabbit ventricular myocardium

1990 • 122 citations

Characterization of angiotensin II receptor subtypes in rat liver.

1984 • 108 citations

A Role for the Adrenal Renin-Angiotensin System in the Regulation of Potassium-Stimulated Aldosterone Production*

1985 • 105 citations

The rat angiotensin II AT1A receptor couples with three different signal transduction pathways

1992 • 97 citations

Angiotensin II induces endothelium-dependent vasodilation of rat cerebral arterioles

1990 • 97 citations

Endothelium-dependent modulation of angiotensin II-induced contraction in blood vessels

1988 • 90 citations

Angiotensin II-Binding Sites in Rat and Primate Isolated Renal Tubular Basolateral Membranes*

1983 • 89 citations

Heterogeneity in Vascular Smooth Muscle Responsiveness to Angiotensin II

1995 • 87 citations

Angiotensin II receptors negatively coupled to adenylate cyclase in rat aorta

1983 • 84 citations

Angiotensin II‐elicited signal transduction via AT₁ receptors in endothelial cells

1996 • 81 citations

The intrarenal renin-angiotensin system.

1993 • 78 citations

The intrarenal renin-angiotensin system

1993 • 74 citations

Angiotensin II inhibits adenylate cyclase from adrenal cortex glomerulosa zone

1983 • 70 citations

Importance of Tyrosine Phosphorylation in Angiotensin II Type 1 Receptor Signaling

1996 • 65 citations

A cloned angiotensin receptor isoform from the turkey adrenal gland is pharmacologically distinct from mammalian angiotensin receptors.

1993 • 65 citations

The Ligand Binding Signatures of the Rat AT1A, AT1B and the Human AT1 Receptors Are Essentially Identical

1993 • 60 citations

Angiotensin II signalling events mediated by tyrosine phosphorylation

1996 • 56 citations

Autoradiographic characterization of angiotensin II receptor subtypes in rat intestine

1993 • 51 citations

Angiotensin receptors in pulmonary arterial and aortic endothelial cells

1989 • 50 citations

Vascular smooth-muscle cells contain AT1 angiotensin receptors coupled to phospholipase D activation

1994 • 49 citations

Metabolism of angiotensins II and III by membrane-bound peptidases from rat brain.

1988 • 47 citations

Angiotensin II Increases cGMP Content Via Endothelial Angiotensin II AT1 Subtype Receptors in the Rat Carotid Artery

1995 • 47 citations

Endothelium-dependent, nitric oxide-mediated inhibition of angiotensin II-induced contractions in rabbit aorta

1994 • 45 citations

The Renin-Angiotensin System

1994 • 39 citations

Angiotensin II Type 2 Receptor–Mediated Regulation of Rat Neuronal K ⁺ Channels

1996 • 35 citations

Angiotensin II-induced endothelium-dependent relaxation of fowl aorta

1993 • 35 citations

Chromosomal Localization of Angiotensin II Type 1 Receptor Isoforms in the Rat

1993 • 34 citations

The Importance of Tyrosine Phosphorylation in Angiotensin II Signaling

1996 • 33 citations

Novel angiotensin receptor subtypes in fowl

1994 • 29 citations

Angiotensin II relaxation of rainbow trout vessels in vitro

1994 • 29 citations

The angiotensin (AT1) receptor.

1993 • 28 citations

Identification of the angiotensin II receptor in rat mesenteric artery

1984 • 25 citations

Molecular cloning, expression and tissue distribution of a chicken angiotensin II receptor

1996 • 24 citations

Angiotensin II: Biosynthesis, molecular recognition, and signal transduction

1995 • 23 citations

Conversion and degradation of [125I] labelled angiotensin I in isolated perfused porcine coronary and carotid arteries

1995 • 22 citations

Skylab Report: Man's Role in Space Research

1974 • 9 citations

Conversion and degradation of [125I] labelled angiotensin I in isolated perfused porcine coronary and carotid arteries

1995 • 5 citations