Nitrous oxide has multiple deleterious effects on cobalamin metabolism and causes decreases in activities of both mammalian cobalamin-dependent enzymes in rats.

MYELONEUROPATHY AFTER PROLONGED EXPOSURE TO NITROUS OXIDE

1978 • 377 citations

TREATMENT OF TETANUS SEVERE BONE-MARROW DEPRESSION AFTER PROLONGED NITROUS-OXIDE ANESTHESIA

1956 • 354 citations

MEGALOBLASTIC HÆMOPOIESIS IN PATIENTS RECEIVING NITROUS OXIDE

1978 • 298 citations

Cobalamin Analogues Are Present in Human Plasma and Can Mask Cobalamin Deficiency because Current Radioisotope Dilution Assays Are Not Specific for True Cobalamin

1978 • 262 citations

Neuropathy following abuse of nitrous oxide

1978 • 215 citations

SELECTIVE INACTIVATION OF VITAMIN B12 IN RATS BY NITROUS OXIDE

1978 • 195 citations

Teratogenic Activity of Nitrous Oxide

1967 • 165 citations

Absorption, Plasma Transport, and Cellular Retention of Cobalamin Analogues in the Rabbit

1977 • 136 citations

Mitotic Synchrony in Mammalian Cells Treated with Nitrous Oxide at High Pressure

1968 • 125 citations

Neuropathology of experimental vitamin B ¹² deficiency in monkeys

1976 • 118 citations

Criteria for a Recommended Standard… Occupational Exposure to Waste Anesthetic Gases and Vapors

1978 • 115 citations

Metabolism of Propionic Acid in Animal Tissues

1965 • 115 citations

Recognition of two intracellular cobalamin binding proteins and their identification as methylmalonyl-CoA mutase and methionine synthetase.

1977 • 104 citations

Human plasma R-type vitamin B12-binding proteins. II. The role of transcobalamin I, transcobalamin III, and the normal granulocyte vitamin B12-binding protein in the plasma transport of vitamin B12.

1975 • 103 citations

Abnormal Fatty Acid Metabolism in Peripheral Nerves of Patients with Pernicious Anemia

1973 • 100 citations

Intracellular binding of radioactive hydroxocobalamin to cobalamin-dependent apoenzymes in rat liver.

1977 • 78 citations

Effects of Nitrous Oxide Inhalation on Hemopoiesis in Rats

1963 • 70 citations

Neurological changes in fruit bats deficient in vitamin B12

1975 • 61 citations

Leucine 2,3-aminomutase, an enzyme of leucine catabolism.

1976 • 55 citations

Isolation of Gastric Vitamin B12-binding Proteins Using Affinity Chromatography

1973 • 53 citations

Occupational disease among operating room personnel: a national study. Report of an Ad Hoc Committee on the Effect of Trace Anesthetics on the Health of Operating Room Personnel, American Society of Anesthesiologists.

1974 • 48 citations

Presence of cobalamin analogues in animal tissues

1980 • 46 citations

Effect of Nitrous Oxide on the White-Cell Count in Leukemia

1963 • 46 citations

LEUCOPENIC EFFECTS OF PROLONGED NITROUS OXIDE TREATMENT

1967 • 43 citations

The Neuropathology of Experimental Vitamin B6Deficiency in Monkeys

1956 • 42 citations

Improved techniques for the extraction and chromatography of cobalamins

1978 • 41 citations

Hematologic reaction to prolonged exposure to nitrous oxide.

1977 • 39 citations

Separation and determination of cobalamins on an SP-Sephadex column

1970 • 35 citations

Recognition and Resolution of Errors in the Radioisotopic Assay of Serum Vitamin B₁₂

1970 • 33 citations

Cobalamin-dependent formation of leucine and beta-leucine by rat and human tissue. Changes in pernicious anemia.

1980 • 33 citations

The Role of Cobamides in Methionine Synthesis

1966 • 28 citations

‘Recreational’ misuse of nitrous oxide

1979 • 26 citations

Remission in chronic myeloid leucaemia following prolonged nitrous oxide inhalation.

1959 • 23 citations

Isolation of cobalamin and cobalamin analogs by reverse affinity chromatography

1978 • 17 citations

Strain Sensitivity of Rats to Nitrous Oxide

1968 • 16 citations

The Effect of Nitrous Oxide on the Cell Cycle in Human Bone Marrow

1979 • 15 citations

EXPERIMENTAL STUDIES INTO THE EFFECT OF NITROUS OXIDE ON TUMOUR CELL GROWTH

1967 • 11 citations

TERATOGENIC ACTIVITY OF NITROUS OXIDE

1968 • 3 citations