Epstein-Barr Virus Infection Alters Cellular Signal Cascades in Human Nasopharyngeal Epithelial Cells

Epstein–Barr virus: 40 years on

2004 • 2,079 citations

STATs in oncogenesis

2000 • 1,723 citations

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

2002 • 1,160 citations

Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

2000 • 1,150 citations

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

2003 • 1,132 citations

Focus on nasopharyngeal carcinoma

2004 • 546 citations

Epstein–Barr virus and oncogenesis: from latent genes to tumours

2003 • 540 citations

STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunity

2003 • 389 citations

Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus

1999 • 380 citations

Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis

2004 • 317 citations

Cell-to-Cell Contact as an Efficient Mode of Epstein-Barr Virus Infection of Diverse Human Epithelial Cells

1998 • 314 citations

Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis

2004 • 305 citations

Epstein-Barr Virus LMP2A Transforms Epithelial Cells, Inhibits Cell Differentiation, and Activates Akt

2000 • 279 citations

Induction of cyclooxygenase-2 by Epstein–Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells

2001 • 260 citations

Epstein-Barr virus RNA confers resistance to interferon-alpha-induced apoptosis in Burkitt's lymphoma

2002 • 259 citations

Establishment of a cell line (NPC/HK1) from a differentiated squamous carcinoma of the nasopharynx

1980 • 212 citations

High frequency of chromosome 3p deletion in histologically normal nasopharyngeal epithelia from southern Chinese.

2000 • 202 citations

Epstein–Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway

2004 • 200 citations

Establishment of two immortalized nasopharyngeal epithelial cell lines using SV40 large T and HPV16E6/E7 viral oncogenes

2002 • 182 citations

A Positive Autoregulatory Loop of LMP1 Expression and STAT Activation in Epithelial Cells Latently Infected with Epstein-Barr Virus

2003 • 164 citations

Characterization of seven newly established nasopharyngeal carcinoma cell lines.

1993 • 146 citations

STATs as critical mediators of signal transduction and transcription: lessons learned from STAT5

2004 • 140 citations

The Relationship Between Microvessel Density, the Expression of Vascular Endothelial Growth Factor (VEGF), and the Extension of Nasopharyngeal Carcinoma

2000 • 109 citations

Requirement for Cell-to-Cell Contact in Epstein-Barr Virus Infection of Nasopharyngeal Carcinoma Cells and Keratinocytes

1999 • 105 citations

Constitutive activation of STAT3 and STAT5 is present in the majority of nasopharyngeal carcinoma and correlates with better prognosis

2003 • 100 citations

Roles of Epstein–Barr virus glycoproteins gp350 and gp25 in the infection of human epithelial cells

2001 • 84 citations

Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNα

2004 • 78 citations

Alterations of Biologic Properties and Gene Expression in Nasopharyngeal Epithelial Cells by the Epstein-Barr Virus–Encoded Latent Membrane Protein 1

2003 • 70 citations

Phenotypic alterations induced by the Hong Kong‐prevalent Epstein‐Barr virus‐encoded LMP1 variant (2117‐LMP1) in nasopharyngeal epithelial cells

2004 • 51 citations

Stable expression of EBERs in immortalized nasopharyngeal epithelial cells confers resistance to apoptotic stress

2005 • 50 citations