Metabolism of the carcinogen 1,2-dimethylhydrazine by isolated human colon microsomes and human colon tumor cells in culture

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

1968 • 1,691 citations

Promoting effect of bile acids in colon carcinogenesis in germ-free and conventional F344 rats.

1977 • 436 citations

Human colonic adenocarcinoma cells

1976 • 375 citations

Aryl hydrocarbon (benzo[a]pyrene) hydroxylase in microsomes from rat tissues: Differential inhibition and stimulation by benzoflavones and organic solvents

1971 • 374 citations

ESTIMATION OF FORMALDEHYDE IN BIOLOGICAL MIXTURES

1945 • 371 citations

Investigations into the metabolism and mode of action of the colon carcinogens 1,2-dimethylhydrazine and azoxymethane

1977 • 328 citations

Selektive Erzeugung von Darmkrebs bei Ratten durch 1,2-Dimethyl-hydrazin

1967 • 273 citations

Colon carcinogens: Their metabolism and mode of action

1971 • 234 citations

Carcinoma of the Colon and Antecedent Epithelium.

1971 • 213 citations

EPIDEMIOLOGY OF LARGE-BOWEL CANCER

1971 • 207 citations

Metabolism of cyclophosphamide by rat hepatic microsomes.

1971 • 157 citations

Inhibitory effects of beta-diethylaminoethyl diphenylpropylacetate on a variety of drug metabolic pathways in vitro.

1954 • 143 citations

Explant culture of human colon

1978 • 127 citations

Pathology of Intestinal Neoplasms and Other Lesions in Rats Exposed to Azoxymethane

1973 • 111 citations

Metabolism of benzo(a)pyrene and identification of the major benzo(a)pyrene-DNA adducts in cultured human colon.

1978 • 107 citations

Further leads on metabolic epidemiology of large bowel cancer.

1975 • 99 citations

Dietary effects on chemical carcinogenesis in animal models for colon and liver tumors.

1975 • 85 citations

The drug and carcinogen metabolism system of rat colon microsomes

1978 • 76 citations

The occurrence of methylazoxymethanol in Cycas circinalis L.

1963 • 71 citations

Activation of carcinogens and mutagens by rat colon mucosa.

1978 • 69 citations

Decomposition of Methylazoxymethanol, the Aglycone of Cycasin, in D2O

1972 • 53 citations

Inhibition of the metabolism of the colon carcinogen, azoxymethane, by pyrazole.

1978 • 49 citations

The epidemiology of cancer of the large bowel

1974 • 47 citations

Longitudinal karyotype and genetic signature analysis of cultured human colon adenocarcinoma cell lines LS180 and LS174T.

1980 • 41 citations

Early alterations in rat colonic mucosal cyclic nucleotide metabolism and protein kinase activity induced by 1,2-dimethylhydrazine.

1980 • 40 citations

Binding of Chemical Carcinogens to Macromolecules in Cultured Human Colon: Brief Communication2

1977 • 39 citations

Human Colon Adenocarcinoma Cells. II. Tumorigenic and Organoid Expression In Vivo and In Vitro2

1977 • 38 citations

Transplantation of Chemically Induced Metastatic Mucinous Adenocarcinomas of the Jejunum and Colon in Rats

1973 • 33 citations

Comments on the epidemiology of large bowel cancer.

1975 • 24 citations

Control by gastrointestinal hormones of the hydroxylation of the carcinogen benzo(a)pyrene and other xenobiotics in rat colon.

1981 • 22 citations

Transplantation of chemically induced adenocarcinomas of the colon in an inbred strain of rats

1974 • 19 citations

Cell Differentiation and the Development of Colonic Neoplasms

1970 • 16 citations

The drug metabolism systems of liver and liver tumors: A comparison of activities and characteristics

1978 • 16 citations

Degenerative behavior of epithelial cells in the colonic crypt of the mouse following administration of colonic carcinogen, 1,2-dimethylhydrazine

1981 • 7 citations