Age dependency of cystathionine beta-synthase activity in human fibroblasts in homocyst(e)inemia and atherosclerotic vascular disease

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Metabolic Basis of Inherited Disease.

1988 • 7,933 citations

The serial cultivation of human diploid cell strains

1961 • 7,886 citations

The Metabolic Basis of Inherited Disease.

1983 • 2,885 citations

Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease

1991 • 2,191 citations

Disorders of transsulfuration

1989 • 1,053 citations

Heterozygosity for Homocystinuria in Premature Peripheral and Cerebral Occlusive Arterial Disease

1985 • 739 citations

The relationship between in vitro cellular aging and in vivo human age.

1976 • 559 citations

The pathogenesis of coronary artery disease. A possible role for methionine metabolism.

1976 • 535 citations

Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease.

1989 • 510 citations

Transsulfuration in Mammals

1965 • 403 citations

Impaired homocysteine metabolism in early-onset cerebral and peripheral occlusive arterial disease Effects of pyridoxine and folic acid treatment

1990 • 397 citations

Plasma homocysteine before and after methionine loading with regard to age, gender, and menopausal status

1992 • 321 citations

Protein-bound homocyst(e)ine. A possible risk factor for coronary artery disease.

1986 • 307 citations

Moderate homocysteinemia--a possible risk factor for arteriosclerotic cerebrovascular disease.

1984 • 290 citations

The Cell Biology of Human Aging

1976 • 235 citations

Down's syndrome: an atheroma-free model?

1977 • 213 citations

Homocysteine and myocardial infarction

1988 • 197 citations

DIABETES MELLITUS AND AGING: DIMINISHED PLATING EFFICIENCY OF CULTURED HUMAN FIBROBLASTS

1969 • 186 citations

Unique efficiency of methionine metabolism in premenopausal women may protect against vascular disease in the reproductive years.

1983 • 152 citations

Cystathionine Synthase in Tissue Culture Derived from Human Skin: Enzyme Defect in Homocystinuria

1968 • 146 citations

Methionine intolerance: A possible risk factor for coronary artery disease

1985 • 144 citations

A mild procedure for the rapid release of cytoplasmic enzymes from cultured animal cells

1979 • 144 citations

Homocysteinemia, ischemic heart disease, and the carrier state for homocystinuria

1983 • 138 citations

Homocystinuria

1978 • 118 citations

Folic acid responsive postmenopausal homocysteinemia

1985 • 105 citations

Cystathionine beta synthase: Gene dosage effect in trisomy 21

1985 • 101 citations

Detection of heterozygotes for homocystinuria: Study of sulphur-containing amino acids in plasma and urine after L-methionine loading

1974 • 92 citations

Improved identification of heterozygotes for homocystinuria due to cystathionine synthase deficiency by the combination of methionine loading and enzyme determination in cultured fibroblasts

1985 • 92 citations

Homocystinuria

1966 • 88 citations

Homocystinuria due to cystathionine synthase deficiency: Enzymatic and ultrastructural studies

1974 • 73 citations

Homocystinuria: Metabolic studies on 3 patients

1965 • 68 citations

Assignment of the gene for cystathionine ?-synthase to human chromosome 21 in somatic cell hybrids

1984 • 67 citations

Homocystinuria: Studies in Tissue Culture

1973 • 65 citations

Effects of donor age on protein and collagen synthesis in vitro by human diploid fibroblasts.

1986 • 57 citations

Cystathionine synthase deficiency: Heterozygote detection using cultured skin fibroblasta

1973 • 37 citations

Detection of heterozygotes for recessive alleles. Homocyst(e)inemia: Paradigm of Pitfalls in phenotypes

1990 • 36 citations

Effect of chronologic age on induction of cystathionine synthase, uroporphyrinogen I synthase, and glucose-6-phosphate dehydrogenase activities in lymphocytes.

1981 • 31 citations

AGING AND VARIABILITY

1966 • 29 citations

Homocystinuria: Studies on cystathionine β‐synthase,S‐adenosylmethionine synthetase and cystathionase activities in skin fibroblasts

1981 • 27 citations

Protein‐bound plasma homocyst(e)ine and identification of heterozygotes for cystathionine‐synthase deficiency

1985 • 26 citations

Effect of Donor Age on Clonal Differentiation of Human Skin Fibroblasts in vitro

1985 • 14 citations

Effects of heparin and dextran sulphate on the production of collagen and protein in diabetic and non-diabetic human skin fibroblast cultures.

1983 • 7 citations

Homocystinuria: The effect of pyridoxine supplementation on cultured skin fibroblasts

1981 • 4 citations