Protein variations associated with Lesch-Nyhan syndrome.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Ultrasensitive Stain for Proteins in Polyacrylamide Gels Shows Regional Variation in Cerebrospinal Fluid Proteins

1981 • 2,972 citations

A familial disorder of uric acid metabolism and central nervous system function

1964 • 1,448 citations

Enzyme Defect Associated with a Sex-Linked Human Neurological Disorder and Excessive Purine Synthesis

1967 • 1,210 citations

A highly sensitive silver stain for detecting proteins and peptides in polyacrylamide gels

1979 • 1,089 citations

Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency in Gout

1969 • 452 citations

Trace polypeptides in cellular extracts and human body fluids detected by two-dimensional electrophoresis and a highly sensitive silver stain.

1979 • 391 citations

A rapid sensitive silver stain for polypeptides in polyacrylamide gels

1981 • 379 citations

Biochemical Bases of Accelerated Purine Biosynthesis de Novo in Human Fibroblasts Lacking Hypoxanthine-Guanine Phosphoribosyltransferase

1968 • 251 citations

Advances in Human Genetics 8

1977 • 98 citations

Purification of IMP:Pyrophosphate Phosphoribosyltransferases, Catalytically Incompetent Enzymes in Lesch-Nyhan Disease

1971 • 93 citations

Human heterozygosity: a new estimate.

1979 • 88 citations

Human IMP dehydrogenase

1974 • 79 citations

Substrate Stabilization: Genetically Controlled Reciprocal Relationship of Two Human Enzymes

1970 • 77 citations

Hypoxanthine-guanine phosphoribosyltransferase: characteristics of the mutant enzyme in erythrocytes from patients with the Lesch-Nyhan syndrome

1972 • 63 citations

Human hypoxanthine phosphoribosyltransferase. Purification and properties

1977 • 44 citations

Electrophoretic properties of hypoxanthine-guanine phosphoribosyl transferase in erythrocytes of subjects with Lesch-Nyhan syndrome

1972 • 42 citations

Radioimmune determination of hypoxanthine phosphoribosyltransferase crossreacting material in erythrocytes of Lesch-Nyhan patients.

1975 • 42 citations

Inosinic acid dehydrogenase activity in the Lesch-Nyhan syndrome

1972 • 39 citations

Biochemical Evidence for a Distinct Type of Primary Gout

1967 • 37 citations

Hypoxanthine phosphoribosyltransferase deficiency: association of reduced catalytic activity with reduced levels of immunologically detectable enzyme protein.

1975 • 36 citations

Hypoxanthine Phosphoribosyltransferase: Two-Dimensional Gels from Normal and Lesch-Nyhan Hemolyzates

1977 • 34 citations

Characterization of the subunit composition of HGPRTase from human erythrocytes and cultured fibroblasts

1980 • 31 citations

Immunochemical studies of AMP:pyrophosphate phosphoribosyltransferase from normal and Lesch—Nyhan subjects

1973 • 21 citations

Human hypoxanthine-guanine phosphoribosyltransferase: studies on the normal and mutant forms of the enzyme.

1973 • 19 citations

Pathological and immunological observations in a case of Lesch-Nyhan-syndrome

1979 • 13 citations

Reaction of antibody to normal human hypoxanthine phosphoribosyltransferase with products of mutant genes

1976 • 12 citations

Hypoxanthine guanine phosphoribosyl‐transferase (HGPRT)

1979 • 9 citations