Cefotaxime-hydrolysing activity of the β-lactamase ofKlebsiella oxytocaD488 could be related to a threonine residue at position 140

The structure of β-lactamases

1980 • 1,705 citations

Extended-spectrum beta-lactamases

1989 • 808 citations

Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.

1978 • 791 citations

Evolution of plasmid-coded resistance to broad-spectrum cephalosporins

1985 • 421 citations

ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase type.

1981 • 384 citations

Bacterial Resistance to β-Lactam Antibiotics: Crystal Structure of β-Lactamase from Staphylococcus aureus PC1 at 2.5 Å Resolution

1987 • 349 citations

The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 <scp>dd</scp>-peptidase family

1988 • 334 citations

β‐Lactamase of Bacillus licheniformis 749/C at 2 Å resolution

1990 • 175 citations

Klebsiella pneumoniae and Other Enterobacteriaceae Producing Novel Plasmid-Mediated -Lactamases Markedly Active Against Third-Generation Cephalosporins: Epidemiologic Studies

1988 • 169 citations

Penicillinase from Bacillus licheniformis: nucleotide sequence of the gene and implications for the biosynthesis of a secretory protein in a Gram-positive bacterium

1981 • 160 citations

Sequence of PSE-2 beta-lactamase

1988 • 156 citations

Computerized microacidimetric determination of β lactamase Michaelis—Menten constants

1973 • 134 citations

Chromosomal beta-lactamase of Klebsiella oxytoca, a new class A enzyme that hydrolyzes broad-spectrum beta-lactam antibiotics

1989 • 117 citations

Single amino acid substitution between SHV‐1 β‐lactamase and cefotaxime‐hydrolyzing SHV‐2 enzyme

1988 • 105 citations

Use of statistical criteria for screening potential homologies in nucleic acid sequences

1984 • 95 citations

Complete amino acid sequence of p453-plasmid-mediated PIT-2 β-lactamase (SHV-1)

1988 • 92 citations

Detection of extended broad-spectrum beta-lactamases inEnterobacteriaceae in four French hospitals

1989 • 71 citations

Nucleotide sequence of the gene encoding the Streptomyces albus G beta-lactamase precursor

1987 • 65 citations

Nucleotide sequence of the PSE-4 carbenicillinase gene and correlations with the Staphylococcus aureus PC1 beta-lactamase crystal structure.

1990 • 64 citations

The epidemiology of -lactamases

1989 • 60 citations

Nucleotide sequence and expression of the beta-lactamase gene from Staphylococcus aureus plasmid pI258 in Escherichia coli, Bacillus subtilis, and Staphylococcus aureus

1987 • 58 citations

Interactions of New Plasmid-Mediated -Lactamases with Third-Generation Cephalosporins

1988 • 53 citations

The nature of the genetic determinant for the SHV-1 β-lactamase

1979 • 52 citations

The phototrophic bacterium Rhodopseudomonas capsulata sp108 encodes an indigenous class A β-lactamase

1989 • 47 citations

Molecular Analysis of -Lactamases from Four Species of Streptomyces: Comparison of Amino Acid Sequences with those of other -clactamases

1990 • 47 citations

Structural features related to hydrolytic activity against ceftazidime of plasmid-mediated SHV-type CAZ-5 beta-lactamase

1989 • 45 citations

Resistance to cephalosporins among gentamicin-resistant klebsiellae

1982 • 41 citations

Excitement in the β-lactamase arena

1989 • 28 citations

Purification and biochemical properties of pitton's type 2 beta-lactamase (SHV 1)

1986 • 27 citations

The K1 β-lactamase of Klebsiella pneumoniae

1987 • 27 citations

[Klebsiella oxytoca beta-lactamases: study of their action on 3d-generation cephalosporins].

1986 • 24 citations