Amyloid fibers are water-filled nanotubes

Huntingtin-Encoded Polyglutamine Expansions Form Amyloid-like Protein Aggregates In Vitro and In Vivo

1997 • 1,283 citations

Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases.

1994 • 1,065 citations

Reversal of Neuropathology and Motor Dysfunction in a Conditional Model of Huntington's Disease

2000 • 1,063 citations

Antibacterial agents based on the cyclic d,l-α-peptide architecture

2001 • 911 citations

Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation

2000 • 714 citations

Molecular genetics: Unmasking polyglutamine triggers in neurodegenerative disease

2000 • 397 citations

The X-ray interpretation of denaturation and the structure of the seed globulins

1935 • 377 citations

Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous β-sheet helix

1996 • 368 citations

Structure of beta-crystallite assemblies formed by Alzheimer beta-amyloid protein analogues: analysis by x-ray diffraction

1993 • 275 citations

Pathogenesis, diagnosis and treatment of systemic amyloidosis

2001 • 229 citations

Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid β-peptide of amyloid plaques

2002 • 220 citations

Cause of neural death in neurodegenerative diseases attributable to expansion of glutamine repeats

2001 • 199 citations

Direct visualisation of the β-sheet structure of synthetic Alzheimer’s amyloid 1 1Edited by F. E. Cohen

2000 • 174 citations

Conformation and Fibrillogenesis of Alzheimer Aβ Peptides with Selected Substitution of Charged Residues

1994 • 152 citations

The composition and swelling properties of haemoglobin crystals

1946 • 123 citations

Glutamine repeats and neurodegenerative diseases: molecular aspects

2001 • 7 citations