Combined Antisense and Pharmacological Approaches Implicate hTASK as an Airway O2 Sensing K+Channel

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Inhalational anesthetics activate two-pore-domain background K+ channels

1999 • 637 citations

TASK, a human background K+ channel to sense external pH variations near physiological pH

1997 • 619 citations

Molecular and functional properties of two-pore-domain potassium channels

2000 • 591 citations

TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure.

1996 • 532 citations

Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel.

1996 • 483 citations

Oxygen sensing in airway chemoreceptors

1993 • 467 citations

A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids

1998 • 453 citations

An oxygen‐, acid‐ and anaesthetic‐sensitive TASK‐like background potassium channel in rat arterial chemoreceptor cells

2000 • 421 citations

Mechano- or Acid Stimulation, Two Interactive Modes of Activation of the TREK-1 Potassium Channel

1999 • 404 citations

TASK-3, a New Member of the Tandem Pore K+ Channel Family

2000 • 369 citations

Cloning and Expression of a Novel pH-sensitive Two Pore Domain K+ Channel from Human Kidney

1998 • 354 citations

Contributions of Kv3 Channels to Neuronal Excitability

1999 • 308 citations

TASK-3, a Novel Tandem Pore Domain Acid-sensitive K+Channel

2000 • 303 citations

Hypoxic suppression of K+ currents in type I carotid body cells: Selective effect on the Ca2+-activated K+ current

1990 • 280 citations

A functional role for the two-pore domain potassium channel TASK-1 in cerebellar granule neurons

2000 • 256 citations

The TASK-1 Two-Pore Domain K⁺ Channel Is a Molecular Substrate for Neuronal Effects of Inhalation Anesthetics

2000 • 251 citations

An Open Rectifier Potassium Channel with Two Pore Domains in Tandem Cloned from Rat Cerebellum

1998 • 248 citations

Hypoxia-sensitive neuro-epithelial bodies intrapulmonary secretory neuroreceptors, modulated by the CNS

1973 • 248 citations

NADPH oxidase is an O ₂ sensor in airway chemoreceptors: Evidence from K ⁺ current modulation in wild-type and oxidase-deficient mice

2000 • 194 citations

NADPH-oxidase and a hydrogen peroxide-sensitive K ⁺ channel may function as an oxygen sensor complex in airway chemoreceptors and small cell lung carcinoma cell lines

1996 • 193 citations

Expression of neuroendocrine cell markers L-dopa decarboxylase, chromogranin A, and dense core granules in human tumors of endocrine and nonendocrine origin.

1988 • 184 citations

Dimerization of TWIK-1 K+ channel subunits via a disulfide bridge.

1996 • 170 citations

Proton Block and Voltage Gating Are Potassium-dependent in the Cardiac Leak Channel Kcnk3

2000 • 160 citations

Characterization of TASK‐4, a novel member of the pH‐sensitive, two‐pore domain potassium channel family

2001 • 150 citations

Neuroepithelial bodies as airway oxygen sensors

1999 • 150 citations

Oxygen-sensing by ion channels and the regulation of cellular functions

1996 • 137 citations

Hypoxia‐induced catecholamine secretion in isolated newborn rat adrenal chromaffin cells is mimicked by inhibition of mitochondrial respiration

1997 • 125 citations

Oxygen-sensitive ion channels

1997 • 96 citations

Functional characterisation of human TASK-3, an acid-sensitive two-pore domain potassium channel

2001 • 93 citations

O₂‐sensitive K⁺ channels: role of the Kv1.2 α‐subunit in mediating the hypoxic response

2000 • 92 citations

Immunocytochemical localization of O2-sensing protein (NADPH oxidase) in chemoreceptor cells

1997 • 78 citations

O2 Sensing by Airway Chemoreceptor-derived Cells

2000 • 74 citations

Selective modulation of membrane currents by hypoxia in intact airway chemoreceptors from neonatal rabbit

1999 • 71 citations

Oxygen-sensing by ion channels and the regulation of cellular functions

1996 • 66 citations

The Contribution of Dendritic Kv3 K⁺Channels to Burst Threshold in a Sensory Neuron

2001 • 51 citations

pH‐Dependent Interactions of Cd²⁺ and a Carboxylate Blocker with the Rat ClC‐1 Chloride Channel and Its R304E Mutant in the Sf‐9 Insect Cell Line

1997 • 49 citations

Modulation of transient outward current by extracellular protons and Cd²⁺ in rat and human ventricular myocytes

1998 • 37 citations