Prognostic significance of the pattern of aortic root dilation in the Marfan syndrome

Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene

1991 • 2,004 citations

Heritable Disorders of Connective Tissue

1960 • 1,560 citations

Two-dimensional echocardiographic aortic root dimensions in normal children and adults

1989 • 1,088 citations

Life Expectancy and Causes of Death in the Marfan Syndrome

1972 • 752 citations

International nosology of heritable disorders of connective tissue, Berlin, 1986

1988 • 704 citations

Association of aortic dilation with regurgitant, stenotic and functionally normal bicuspid aortic valves

1992 • 408 citations

ON THE LAWS OF INHERITANCE IN MAN: I. INHERITANCE OF PHYSICAL CHARACTERS

1903 • 289 citations

The spectrum of cardiovascular disease in the Marfan syndrome: A clinico-morphologic study of 18 necropsy patients and comparison to 151 previously reported necropsy patients

1982 • 253 citations

Aortic root dilatation and mitral valve prolapse in Marfan's syndrome: an ECHOCARDIOgraphic study.

1975 • 244 citations

Pulsed Doppler echocardiography in the diagnosis and estimation of severity of aortic insufficiency

1982 • 211 citations

Surgical Treatment of Aneurysms of the Ascending Aorta in the Marfan Syndrome

1986 • 204 citations

Diagnosis and classification of severity of mitral valve prolapse: Methodologic, biologic, and prognostic considerations

1987 • 187 citations

Heritable Disorders of Connective Tissue

1973 • 171 citations

Marfan's syndrome: natural history and long-term follow-up of cardiovascular involvement

1989 • 165 citations

Aortic Root Dilatation as a Cause of Isolated, Severe Aortic Regurgitation

1987 • 160 citations

Impact of cardiovascular operation on survival in the Marfan patient.

1989 • 134 citations

Echocardiographic detection of mitral valve prolapse. Exclusion of false positive diagnosis and determination of inheritance.

1975 • 134 citations

Composite graft repair of Marfan aneurysm of the ascending aorta: Results in 100 patients

1991 • 125 citations

Two mutations in Marfan syndrome resulting in truncated fibrillin polypeptides.

1992 • 117 citations

THE MARFAN SYNDROME

1960 • 114 citations

Comparison of cardiovascular and skeletal features of primary mitral valve prolapse and Marfan syndrome

1989 • 92 citations

Cardiac, skeletal, and ocular abnormalities in patients with Marfan's syndrome and in their relatives. Comparison with the cardiac abnormalities in patients with kyphoscoliosis.

1984 • 68 citations

Echocardiographic assessment of cardiovascular abnormalities in the Marfan syndrome

1983 • 56 citations

A SIMPLE SCREENING TEST FOR THE MARFAN SYNDROME

1966 • 45 citations

The wrist sign. A useful physical finding in the Marfan syndrome

1970 • 45 citations

Recurrence risks for nonsyndromic external ear malformations.

1979 • 33 citations

The Wrist Sign

1970 • 29 citations

Elucidation of the gene defect in Marfan syndrome Success by two complementary research strategies

1992 • 12 citations