Expression of Co-stimulatory 4-1BB Ligand Induces Significant Tumor Regression and Protective Immunity

CD28/B7 SYSTEM OF T CELL COSTIMULATION

1996 • 2,726 citations

The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death

1994 • 1,920 citations

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

1992 • 1,573 citations

Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy

1989 • 1,512 citations

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1992 • 1,290 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

1997 • 886 citations

New perspectives of C1328-137-mediated T cell costimulation

1995 • 526 citations

Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity.

1994 • 482 citations

Inducible T cell antigen 4-1BB. Analysis of expression and function.

1993 • 416 citations

cDNA sequences of two inducible T-cell genes.

1989 • 392 citations

Molecular cloning of a ligand for the inducible T cell gene 4‐1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor

1993 • 328 citations

Tumor necrosis factor receptor superfamily members and their ligands

1994 • 313 citations

Tumor Eradication by Adoptive Transfer of Cytototic T Lymphocytes

1992 • 281 citations

Moslecular and biological characterization of human 4‐1BB and its ligands

1994 • 242 citations

Costimulation of T-cell growth

1992 • 225 citations

Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway

1998 • 218 citations

Potential role of 4-1BB in T cell activation. Comparison with the costimulatory molecule CD28.

1995 • 181 citations

4-1BBL Cooperates with B7-1 and B7-2 in Converting a B Cell Lymphoma Cell Line into a Long-Lasting Antitumor Vaccine

1999 • 130 citations

Novel T cell antigen 4-1BB associates with the protein tyrosine kinase p56lck1.

1993 • 62 citations

Marked Reduction in Percentage of Rosette-Forming Thymocytes of Rats During Induction of Bladder Tumors and Restorative Effect of Thymosin In Vitro2

1986 • 19 citations