Continuous cultivation of microorganisms

The Rumen and its Microbes

1966 • 2,491 citations

The maintenance energy of bacteria in growing cultures

1965 • 1,438 citations

The Growth of Micro-organisms in Relation to their Energy Supply

1960 • 956 citations

Synthesis of the Enzymes of the Mandelate Pathway by Pseudomonas putida I. Synthesis of Enzymes by the Wild Type

1966 • 399 citations

AMINO ACID TRANSFER FROM AMINOACYL-RIBONUCLEIC ACIDS TO PROTEIN ON RIBOSOMES OF ESCHERICHIA COLI

1961 • 301 citations

Statistics and dynamics of procaryotic cell populations

1967 • 299 citations

Dynamic measurement of the volumetric oxygen transfer coefficient in fermentation systems

2009 • 278 citations

DNA synthesis in individual L-strain mouse cells

1960 • 275 citations

THE MAINTENANCE REQUIREMENT OF ESCHERICHIA COLI

1963 • 275 citations

The sedimentation behaviour of ribonuclease-active and -inactive ribosomes from bacteria

1965 • 230 citations

The Influence of Maintenance Energy and Growth Rate on the Metabolic Activity, Morphology and Conidiation of Penicillium chrysogenum

1968 • 225 citations

Continuous Culture of Microorganisms

1961 • 202 citations

Dynamics of Microbial Cell Populations

1966 • 199 citations

Synthesis of nucleotide anhydrides by anion exchange

1964 • 198 citations

The Development of Plankton in Relation to Hydrological Regime in the Blue Nile

1967 • 195 citations

A kinetic study of the alcoholic fermentation of grape juice

1967 • 187 citations

Enzyme Pattern and Aerobic Growth of Saccharomyces cerevisiae Under Various Degrees of Glucose Limitation

1968 • 183 citations

Growth Rates of Marine Phytoplankton: Correlation with Light Absorption by Cell Chlorophyll a

1966 • 181 citations

ADENOSINE TRIPHOSPHATE CONTENT OF MARINE BACTERIA1

1967 • 180 citations

Fermentation process kinetics

2000 • 168 citations

Relationship between substrate concentration, growth rate, and respiration rate of Escherichia coli in continuous culture

1964 • 157 citations

Transient and steady states in continuous fermentaion. Theory and experiment

1959 • 156 citations

Mathematics of Microbial Populations

1968 • 152 citations

Growth of Nitrosomonas europaea in batch and continuous culture

1961 • 151 citations

CHARACTERISTICS OF A MARINE NITRIFYING BACTERIUM, NITROSOCYSTIS OCEANUS SP. N.1

1965 • 149 citations

Cumulative feedback inhibition in the multiple end product regulation of glutamine synthetase activity in Escherichiacoli

1964 • 147 citations

Genetics of Regulation of Enzyme Synthesis in the Arginine Biosynthetic Pathway of Escherichia coli

1961 • 140 citations

Dynamics of microbial propagation: Models considering inhibitors and variable cell composition

1967 • 140 citations

Theoretical and Methodological Basis of Continuous Culture of Microorganisms

1966 • 138 citations

The yields of Streptococcus faecalis grown in continuous culture

1960 • 138 citations

Enrichments of aquatic bacteria in continuous culture

1967 • 136 citations

The repression of constitutive β-galactosidase in Escherichia coli by glucose and other carbon sources

1962 • 129 citations

The chemostat: design and instrumentation.

1965 • 120 citations

Continuous Culture of Some Anaerobic and Facultatively Anaerobic Rumen Bacteria

1965 • 118 citations

Theoretical Analysis of Continuous Culture Systems

1966 • 115 citations

Production of Large Amounts of Plant Tissue by Submerged Culture

1959 • 107 citations

Aerobic Microbial Growth at Low Oxygen Concentrations

1967 • 102 citations

STUDIES OF THE GROWTH OF PENICILLIUM CHRYSOGENUM IN CONTINUOUS FLOW CULTURE WITH REFERENCE TO PENICILLIN PRODUCTION

1960 • 101 citations

Magnesium-limited growth of Aerobacter aerogenes in a chemostat

1965 • 100 citations

Accelerated Death of Aerobacter aerogenes Starved in the Presence of Growth-Limiting Substrates

1964 • 98 citations

Effect of p H on Population and Fermentation in a Continuously Cultured Rumen Ecosystem

1966 • 95 citations

Optimal continuous fermentation reactor design

1966 • 94 citations

The Influence of Temperature and pH Value on the Macro-molecular Composition of Magnesium-limited and Glycerol-limited Aerobacter aerogenes Growing in a Chemostat

1965 • 92 citations

Dynamics of the photosynthesis of carbon compounds I. Carboxylation reactions

1960 • 92 citations

SOME INTERACTIONS OF TEMPERATURE, LIGHT INTENSITY, AND NUTRIENT CONCENTRATION DURING THE CONTINUOUS CULTURE OF NITZSCHIA CLOSTERIUM AND TETRASELMIS SP 1

1964 • 91 citations

Chapter 10 Hmdling and Culturing of Chlorella

1964 • 91 citations

Measurement of Unsteady State Growth Rates of Micro-Organisms

1965 • 90 citations

Pullulanase from aerobacter aerogenes; production in a cell-bound state. Purification and properties of the enzyme

1966 • 89 citations

Continuous-Flow Culture of the Filamentous Mould Penicillium Chrysogenum and the Control of its Morphology

1959 • 86 citations

Dynamics of the photosynthesis of carbon compounds II. Amino acid synthesis

1961 • 82 citations

The Rumen Bacteria and Protozoa

1964 • 81 citations

Culture of the marine phytoplankter, Dunaliella tertiolecta, with light-dark cycles

1966 • 80 citations

The Bulk Growth of Animal Cells in Continuous Suspension Culture

1959 • 80 citations

Enhancement in the Blue-Green Alga, Anacystis nidulans

1964 • 80 citations

Enhancement in Chlorella

1963 • 80 citations

SPECIFIC METABOLIC REPRESSION OF THREE INDUCED ENZYMES IN ESCHERICHIA COLI

1963 • 77 citations

DEOXYURIDYLATE KINASE ACTIVITY AND DEOXYURIDINETRIPHOSPHATASE IN ESCHERICHIA COLI

1962 • 76 citations

POLYSACCHARIDE STORAGE AND GROWTH EFFICIENCY IN RUMINOCOCCUS ALBUS

1963 • 73 citations

ATTACHMENT AND GROWTH OF BACTERIA ON SURFACES OF CONTINUOUS-CULTURE VESSELS

1964 • 73 citations

Kinetics of microbial cell growth

1968 • 70 citations

THE CONTINUOUS SUBMERGED CULTIVATION OF PLANT TISSUE AS SINGLE CELLS

1956 • 70 citations

Mutation in continuous cultures. I. Dependence of mutational response upon growth-limiting factors

1964 • 69 citations

BACTERIAL GROWTH UNDER CONDITIONS OF LIMITED NUTRITION*

1963 • 69 citations

Modifications of a Device for Maintenance of the Rumen Microbial Population in Continuous Culture

1964 • 69 citations

Inhibition of photophosphorylation and photosynthetic carbon cycle reactions by fatty acids and esters

1966 • 68 citations

Mutagenic and antimutagenic effects of acridine orange in Escherichia coli

1963 • 68 citations

EXOCELLULAR PRODUCT FORMATION BY MICROORGANISMS IN CONTINUOUS CULTURE. I. PRODUCTION OF 2:3‐BUTANEDIOL BY AEROBACTER AEROGENES IN A SINGLE STAGE PROCESS

1958 • 68 citations

Percentage labeled mitoses curves in exponentially growing cell populations

1968 • 68 citations

Synthesis of the Enzymes of the Mandelate Pathway by Pseudomonas putida III. Isolation and Properties of Constitutive Mutants

1966 • 67 citations

The Survival of Starved Bacteria

1963 • 67 citations

Studies on extracellular proteins from Staphylococcus aureus. IV. Separation of α-toxin by isoelectric focusing

1968 • 66 citations

Biosynthesis of Branched-Chain Amino Acids in Yeast: Regulation of Leucine Biosynthesis in Prototrophic and Leucine Auxotrophic Strains

1968 • 65 citations

A Note on Koch & Schaechter's Hypothesis about Growth and Fission of Bacteria

1964 • 64 citations

Ribosome content and the rate of growth of Salmonella typhimurium

1963 • 64 citations

Continuous propagation of microorganisms

1963 • 63 citations

Catabolite Repression and the Induction of Amidase Synthesis by Pseudomonas aeruginosa 8602 in Continuous Culture

1968 • 63 citations

A continuous culture study of an obligately psychrophilic Pseudomonas species

1967 • 62 citations

Photosynthesis of amino acids

1964 • 62 citations

CONTINUOUS PHASED GROWTH, WITH A MODIFIED CHEMOSTAT

1965 • 61 citations

Automatic Control of Dissolved Oxygen Concentration in Stirred Microbial Cultures

1966 • 61 citations

Measurement of Steady-State Growth Rates of a Thermophilic Alga Directly in Nature

1968 • 61 citations

A New Kinetic Model of a Growing Bacterial Population

1960 • 61 citations

Evidence for the Calvin Cycle and Hexose Monophosphate Pathway in Thiobacillus ferrooxidans

1967 • 61 citations

SECTION OF BIOLOGICAL AND MEDICAL SCIENCES: METHODS, PROBLEMS, AND RESULTS OF GROWING PLANT CELLS UNDER SUBMERGED CONDITIONS*

1960 • 61 citations

A SIMPLIFIED CHEMOSTAT FOR THE GROWTH OF MAMMALIAN CELLS: CHARACTERISTICS OF CELL GROWTH IN CONTINUOUS CULTURE

1961 • 59 citations

Vitamin B₁₂and Marine Ecology III. An experiment with a chemostat

1966 • 59 citations

Physiology of an Obligately Psychrophilic Marine Pseudomonas Species

1968 • 57 citations

Redox potential changes in the 2‐keto‐<scp>L</scp>‐gulonic acid fermentation—I. Correlation between redox potential and dissolved‐oxygen concentration

1961 • 57 citations

Maintenance of the Rumen Microbial Population in Continuous Culture

1963 • 56 citations

Continuous Culture of Torulopsis utilis: A Kinetic Study of Oxygen Limited Growth

1966 • 56 citations

The Coming Industry of Controlled Photosynthesis

1962 • 56 citations

Mean light intensity—a useful concept in correlating growth rates of dense cultures of microalgae

1962 • 56 citations

Budding of Yeast Cells, their Scars and Ageing

1968 • 56 citations

THE SUSTAINED GROWTH OF HUMAN AND ANIMAL CELLS IN A PROTEIN-FREE ENVIRONMENT

1960 • 56 citations

Yield Coefficients of Thiobacillus neapolitanus in Continuous Culture

1967 • 55 citations

The lipids of Listeria monocytogenes

1968 • 55 citations

ANTAGONISM BETWEEN SUBSTRATE AND REPRESSOR IN CONTROLLING THE FORMATION OF A BIOSYNTHETIC ENZYME

1960 • 54 citations

Environmental effects on bacterial copper extraction from low‐grade copper sulfide ores

1967 • 54 citations

Die Bildung von Urease nach Verbrauch der �u�eren N-Quelle bei Hydrogenomonas H16

1966 • 53 citations

A continuous culture apparatus for the microbial utilization of hydrogen produced by electrolysis of water in closed‐cycle space systems

1964 • 53 citations

Continuous flow method in soil microbiology

1965 • 52 citations

The Interrelationship between Potassium, Magnesium and Phosphorus in Potassium-limited Chemostat Cultures of Aerobacter Aerogenes

1966 • 51 citations

Biologische Grundfragen bei der homokontinuierlichen Kultur von Mikroorganismen

1962 • 51 citations

Effect of Dilution Rate and Growth-Limiting Substrate on the Metabolic Activity of Torula utilis Cultures

1965 • 51 citations

Magnesium-limited Growth of Bacillus subtilis, in Pure and Mixed Cultures, in a Chemostat

1967 • 51 citations

THE EFFECT OF LIGHT QUALITY ON THE PRODUCTS OF PHOTOSYNTHESIS IN CHLORELLA VULGARIS

1962 • 51 citations

The cell size and macromolecular composition of Aerobacter aerogenes in various systems of continuous culture

1967 • 51 citations

The effect of equipment scale and degree of mixing on continuous fermentation yield at low dilution rates

1966 • 50 citations

Acceleration of Bacterial Death by Growth Substrates

1963 • 50 citations

Kinetics of hydrogen assimilation in the methane fermentation

1968 • 48 citations

Some Environmental Factors Affecting the Length of Escherichia coli Organisms in Continuous Cultures

1961 • 48 citations

Mathematical models for the product accumulation in microbiolgical processes

1961 • 47 citations

Mixed-Culture Interactions I. Commensalism of Proteus vulgaris with Saccharomyces cerevisiae in Continuous Culture

1965 • 47 citations

MAXIMUM GROWTH RATES OF CHLORELLA IN STEADY-STATE AND IN SYNCHRONIZED CULTURES

1959 • 47 citations

The utilization of mixed sugars in continuous fermentation. I.

1967 • 46 citations

Variation in Content and Distribution of Magnesium, and its Influence on Survival, in Aerobacter Aerogenes Grown in a Chemostat

1966 • 46 citations

Genetic structure of the D-serine deaminase system of Escherichia coli

1964 • 46 citations

The Influence of Temperature and Growth Rate on the Quantitative Relationship Between Potassium, Magnesium, Phosphorus and Ribonucleic Acid of Aerobacter aerogenes Growing in a Chemostat

1966 • 46 citations

Effect of Magnesium on Permeability Control in Chilled Bacteria

1964 • 45 citations

Elongation of Yeast Cells in Continuous Culture

1965 • 45 citations

Theoretical Design of Continuous Antibiotic Fermentation Units

1961 • 45 citations

Toxin production by Clostridium tetani in biphasic liquid cultures

1965 • 44 citations

Oxygen‐absorption rate‐controlled feeding of substrate into aerobic microbial cultures

1966 • 44 citations

INDUCTION BY ARGININE OF ENZYMES OF ARGININE BIOSYNTHESIS IN ESCHERICHIA COLI B

1961 • 44 citations

A CONTINUOUS-FLOW CULTURE APPARATUS: THE CYCLONE COLUMN UNIT

1963 • 44 citations

TRACER TESTS IN FLOW SYSTEMS

1966 • 43 citations

LIPIDS OF CANDIDA UTILIS: CHANGES WITH GROWTH

1966 • 43 citations

Continuous-flow culture of the ERK and L types of mammalian cells

1964 • 42 citations

SOME EFFECTS OF AERATION ON THE GROWTH AND METABOLISM OF SACCHAROMYCES CEREVISIAE IN CONTINUOUS CULTURE

1966 • 42 citations

SPECIFIC EFFECT OF LIMITING NUTRIENT ON PHYSIOLOGICAL EVENTS DURING CULTURE GROWTH

1961 • 41 citations

Inhibition of CO2 fixation by nitrous acid

1965 • 41 citations

MUTATION WITHOUT SEGREGATION

1964 • 41 citations

Continuous flow method in soil microbiology

1961 • 40 citations

Light-Limited Growth of Chlorella in Continuous Cultures

1962 • 40 citations

Oxygen utilization by slime organisms in continuous culture.

1966 • 39 citations

RESOLUTION OF PHAGE-INITIATED AND NORMAL HOST THYMIDYLATE SYNTHETASES OF ESCHERICHIA COLI

1962 • 39 citations

'Take-over'--an Unusual Selection Process in Steady-State Cultures of Escherichia coli

1964 • 38 citations

Population dynamics in suspension cultures of an animal cell strain

1960 • 38 citations

Predicting Production in Light-Limited Continuous Cultures of Algae

1965 • 38 citations

Continuous Culture of Ruminal Microorganisms in Chemically Defined Medium

1962 • 37 citations

SULPHIDE PRODUCTION FROM SULPHATE-ENRICHED SEWAGE SLUDGES

1956 • 37 citations

THE ISOLATION AND CULTURE OF THE NITRIFYING ORGANISMS: PART I. NITROBACTER

1960 • 37 citations

Frequency response analysis of dilution rate effects on yeast growth

1968 • 37 citations

Mutation in continuous cultures

1964 • 36 citations

Control of arginine biosynthesis in strains of Escherichia coli not repressible by arginine

1961 • 35 citations

Multiplication and Fermentation of Saccharomyces cerevisiae under Carbon Dioxide Pressure in Wine

1966 • 35 citations

The intracellular amino acid pool of Candida utilis during growth in batch and continous flow cultures

1965 • 35 citations

The Influence of Environment on Antigen Production by Pasteurella pestis Studied by Means of the Continuous Flow Culture Technique

1961 • 35 citations

Purification of ornithine transcarbamylase from derepressed cells of Escherichia coli W

1962 • 35 citations

Oscillatory growth rate responses of S. Cerevisiae in continuous culture

1967 • 34 citations

THE GLUCOSE UPTAKE KINETICS OF SOME MARINE BACTERIA

1966 • 33 citations

A pilot plant for mammalian cell culture

1968 • 33 citations

Continuous Culture of Yeast on Phenol

1966 • 33 citations

MIXING AND CONTACTING IN CHEMICAL REACTORS

1966 • 33 citations

Submerged growth of cells of higher plants

1960 • 32 citations

THE EFFECT OF THE GROWTH RATE ON THE COMPOSITION OF S. ENTERITIDIS CELL WALLS

1964 • 32 citations

‘Endogenous Factor’ in Sporogenesis in Bacteria

1963 • 32 citations

LATENT MUTANTS IN CHEMOSTATS

1961 • 32 citations

Gibberellic acid formation in continuous culture

1965 • 31 citations

'Substrate-Accelerated Death' of Aerobacter aerogenes

1965 • 31 citations

Effect of Amino Acids on Steady-State Growth of a Group A Hemolytic Streptococcus

1965 • 30 citations

Effect of Growth Rate on the Lipase Activity of a Rumen Bacterium

1966 • 30 citations

Continuous Culture of Rumen Bacteria: Apparatus

1965 • 30 citations

Basis for the Exclusion of Escherichia coli from the Rumen Ecosystem

1965 • 30 citations

The effect of magnesium and of carbon limitation on the macromolecular organisation and metabolic activity of Pseudomonas sp., strain C-iB

1965 • 29 citations

Proliferation of Monkey Kidney Cells in Rotating Cultures

1955 • 29 citations

The Mass Culture of Porphyridium cruentum

1962 • 28 citations

The Carbohydrate Nutrition and Metabolism of a Strain of Mammalian Cells (MB III Strain of Mouse Lymphoblasts) Growing in Vitro

1959 • 28 citations

TWO-PHASE REACTOR DESIGN. TANK-TYPE REACTORS

1968 • 28 citations

Inhibitor studies on the photosynthetic carbon reduction cycle in Chlorella pyrenoidosa

1965 • 27 citations

Glycerol production: A pilot‐plant investigation for continuous fermentation and recovery

1960 • 27 citations

Continuous flow method in soil microbiology

1965 • 27 citations

Environmental Control of Cell Composition in Escherichia coli

1965 • 27 citations

Kinetic studies of gluconic acid fermentations

1965 • 27 citations

Continuous antibiotic fermentation—design of a 20 litre, single‐stage pilot plant and trials with two contrasting processes

1959 • 27 citations

"Substrate-Accelerated Death" of Nitrogen-Limited Bacteria

1966 • 27 citations

Continuous Culture as a Method for Studying Rumen Fermentation

1961 • 27 citations

Bakterielles Wachstum bei geringen Substratkonzentrationen

1963 • 26 citations

MULTI-STAGE CONTINUOUS CULTURE

1964 • 26 citations

CONTINUOUS IN VITRO CULTIVATION OF SPHERULES OFCOCCIDIOIDES IMMITIS

1964 • 26 citations

Environmental Conditions and the Pattern of Metabolism in Algae

1964 • 25 citations

A periodic phenomenon in regulation of pyruvate biosynthesis in Escherichia coli B

1965 • 25 citations

Protein synthesis during photosynthesis

1964 • 25 citations

The Nature and Radiation Sensitivity of the Long Forms of Escherichia coli Strain B/r

1961 • 25 citations

Regulation of Amidase Synthesis by Pseudomonas aeruginosa 8602 in Continuous Culture

1967 • 24 citations

Preparation of Soluble Pertussis Vaccine

1964 • 24 citations

Utilization of Organic Matter by Chlorella Grown in Sewage

1960 • 24 citations

Piston‐flow reactor model for continuous industrial fermentations

1964 • 24 citations

The preparation of ribosomal ribonucleic acid from whole bacteria

1968 • 24 citations

Specific Metabolic Repression of Induced Enzymes in Escherichia Coli

1963 • 23 citations

Mass propagation of algae for photosynthetic gas exchange

1960 • 23 citations

Minimum Requirements for Heterotrophic Growth, and Reserve Substance in Beggiatoa

1963 • 23 citations

Role of Plants in Closed Systems

1964 • 22 citations

Bacterial Growth at Low Population Densities

1962 • 22 citations

CONTINUOUS CULTURE OF BRUCELLA ABORTUS S.19

1961 • 22 citations

The distribution of ribosomal ribonucleic acids among subcellular fractions from bacteria and the adverse effect of the membrane fraction on the stability of ribosomes

1965 • 22 citations

Continuous flow method in soil microbiology

1961 • 22 citations

Production of cell tissue from hydrocarbons by a microbiological process

1965 • 21 citations

The control of the rate of enzyme synthesis in aerobacter aerogenes

1964 • 21 citations

Flexibility in cultivation equipment. I. A small‐scale continuous culture apparatus for the study of complex processes

1964 • 21 citations

Gas Exchange with Mass Cultures of Algae

1963 • 21 citations

Continuous Fermentation of Novobiocin

1961 • 21 citations

The Error Hypothesis of Mutation

1960 • 21 citations

Study of a photosynthetic gas exchanger, a quantitative repetition of the priestley experiment.

1964 • 21 citations

Economic definition of continuous fermentation goals

1963 • 21 citations

Regulation of arginase activity in Chang's liver cells in tissue culture

1965 • 20 citations

Kinetics of induction of mannitol dehydrogenase in Azotobacter agilis

1962 • 20 citations

Studies and observations on the growth of mammalian cells in agitated fluid medium

1960 • 20 citations

Production of Freeze‐dried Brucella abortus Strain 19 Vaccine using Cells produced by Continuous Culture†

1966 • 19 citations

Growth of Chlorella pyrenoidosa in Recycled Medium

1963 • 19 citations

A Genealogical Study of Clonal Development of Escherichia coli

1963 • 19 citations

Nature and Role of Bacterial Contaminants in Mass Cultures of Thermophilic Chlorella pyrenoidosa

1965 • 19 citations

Continuous‐culture system for ecological studies of microorganisms

1966 • 19 citations

Theory of semicontinuous and continuous cultivation applied to the yeastTorula utilis

1961 • 19 citations

Mass Culture of Phytoplankton as Foods for Metazoans

1961 • 19 citations

Design and operation of a pilot‐plant fermentor for the continuous propagation of filamentous microorganisms

1962 • 18 citations

Die kontinuierliche Züchtung von Mikroorganismen als apparatives problem

1965 • 18 citations

Eine automatische Verd�nnungsanlage und ihre Anwendung zur Erzielung homokontinuierlicher Chlorella-Kulturen

1964 • 18 citations

DEVELOPMENTS IN APPARATUS FOR THE CULTURE OF MICRO-ORGANISMS: DESIGN FEATURES OF A LABORATORY TWO STAGE CONTINUOUS FLOW CULTURE APPARATUS

1961 • 18 citations

SULFATE REDUCTION BY BACTERIA

1963 • 18 citations

A Note on the Continuous Flow culture of Mixed Populations of Lactobacilli and Streptococci

1967 • 18 citations

An 8‐liter continuous flow culture apparatus for laboratory production of microorganisms

1965 • 18 citations

Growth of Mixed Cultures on Mixed Substrates

1968 • 18 citations

Interactions of Vibrio cholerae, Shigella flexneri, Enterococci, and Lactobacilli in Continuously Fed Cultures

1961 • 18 citations

A method for the control of the dissolved oxygen tension in microbial cultures

1967 • 18 citations

CONTINUOUS AUTOMATIC MICROBIOLOGICAL ASSAY OF ANTIBIOTICS. PART II

1965 • 18 citations

Steady‐state and synchronous growth of Chlorella pyrenoidosa

1964 • 17 citations

THE RELATIONSHIP BETWEEN MAXIMUM OXYGEN SOLUTION RATES IN A BACTERIAL CULTURE AND IN A SODIUM SULPHITE SOLUTION UNDER COMPARABLE AERATION CONDITIONS

1958 • 17 citations

THEORY OF MULTI-STAGE CONTINUOUS CULTURES

1964 • 17 citations

ENDOGENOUS FACTOR IN SPOROGENESIS IN BACTERIA II

1964 • 17 citations

Microbial Utilization of Hydrocarbons

1941 • 17 citations

Continuous culture in microbial ecology.

1965 • 17 citations

Chemostatic Concentrated Cultures of Heteroploid Mammalian Cell Suspensions in Dialyzing Fermentors

1965 • 17 citations

Control of Protein Level of Algae, Chlorella

1965 • 17 citations

Über die Approximation mit starken de la Vallée-Poussinschen Mitteln

1965 • 17 citations

OBSERVATIONS ON FOAMING AND ITS INHIBITION IN A BACTERIAL CULTURE

1958 • 17 citations

Yield and maintenance analysis in the chemostat; A tool for metabolic studies of growing cells

1968 • 16 citations

The Interaction of Hydrogen Ion, Carbon Dioxide and Potassium Ion in Controlling the Formation of Resistant Sporangia in Blastocladiella emersonii

1965 • 16 citations

[Basic biological problems in homocontinuous culture of microorganisms].

1962 • 16 citations

Biological Aspects of Continuous Cultivation of Microorganisms

1962 • 16 citations

Carbon Dioxide-Limited Growth of Chlorella in Continuous Culture

1962 • 16 citations

Continuous cultivation of micro‐organisms: A new approach and possibilities for its use

1961 • 15 citations

The “Bilthoven unit” for submerged cultivation of microorganisms

1964 • 15 citations

Starter populations as determined under steady state conditions

1965 • 15 citations

UPTAKE AND RETENTION OF Cs¹³⁷ BY A BLUE‐GREEN ALGA IN CONTINUOUS FLOW AND BATCH CULTURE SYSTEMS1

1963 • 15 citations

Protein-disulphide Reductase Activity in Yeast

1966 • 15 citations

An application of the discrete maximum principle to a stagewise biochemical reactor system

1963 • 15 citations

Effects of Growth Rate and Limiting Substrate on Glucose Metabolism in Escherichia coli

1965 • 14 citations

Stability of product limited continuous culture systems

1963 • 14 citations

STRAIN DEGENERATION DURING CONTINUOUS CULTURE OF A CHLORAMPHENICOL-PRODUCING STREPTOMYCES VENEZUELAE

1966 • 14 citations

Lethality in respiratory deficiency and utilization of fermentation energy in petite negative yeasts

1966 • 14 citations

Reversion Rate in Continuous Cultures of an Escherichia coli Auxotroph Exposed to Gamma Rays

1964 • 14 citations

[Effect of propionate concentration on specific growth rate of Propionibacterium shermanii].

1967 • 14 citations

Effect of Deuterium on Starving Bacteria

1964 • 14 citations

Continuous Cultivation of Virus in Cell Suspensions by Use of the Lysostat

1965 • 14 citations

Steady-state suspension culture and metabolism of strain L mouse cells in simple defined medium

1966 • 14 citations

Small‐scale studies of microbiological oxidation of hydrocarbons to long‐chain fatty acids

1961 • 14 citations

Carotenoid biosynthesis in Neurospora crassa: Incorporation of 2-C14-mevalonate during control of pigmentation by continuous culture

1966 • 14 citations

An Intermittent Perfusion and Gas Exchange Method for Continuous Cultivation of Cells in the Rose Chamber

1961 • 14 citations

Continuous cultivations of microorganisms

1974 • 14 citations

Culture of Strain L Cells in Suspension: Replacement of Polymer by Traces of Trypsin in A Defined Medium

1963 • 14 citations

Utilization of Inorganic Nitrogen Compounds by Sphaerotilus natans Growing in a Continuous-Flow Apparatus

1967 • 14 citations

Studies on large-scale methods for propagation of animal cells

1960 • 13 citations

Kleinanlage zur kontinuierlichen Züchtung von Mikroorganismen

1962 • 13 citations

MICROBIAL SULPHIDE PRODUCTION FROM SULPHATE‐ENRICHED SEWAGE SLUDGE

1960 • 13 citations

PREPARATION OF BIOLOGICALLY ACTIVE FRACTIONS OF SALMONELLA TYPHIMURIUM

1961 • 13 citations

Trypsinization of Animal Tissues for Cell Culture: Theoretical Considerations and Automatic Apparatus

1964 • 13 citations

The oxygen uptake of phased yeast cultures growing at different doubling times on nitrogen- and energy-limited media

1968 • 13 citations

A simple device for steady state cultures of microbes

1960 • 13 citations

Continuous flow method in soil microbiology

1965 • 13 citations

Kinetics of the Continuous Alcoholic Fermentation of Blackstrap Molasses

1960 • 13 citations

Apparatus for the Maintenance of Bacterial Cultures in the Steady State

1960 • 13 citations

Yield in continuous aerobic bacterial fermentation

1966 • 13 citations

ENZYMES OF PENTOSE BIOSYNTHESIS: I. SEPARATION OF PENTOSE CYCLE ENZYMES OF ESCHERICHIA COLI

1966 • 12 citations

Continuous cultivation of Escherichia coli possessing high penicillin–acylase activity

1964 • 12 citations

The Effect of Carbonation, Benzoic Acid and pH on the Growth Rate of a Soft Drink Spoilage Yeast as determined by a Turbidostatic Continuous Culture Apparatus

1964 • 12 citations

A New Method for the Microbiological Oxidation of Steroids

1959 • 12 citations

Use of algae for support of the human in space.

1964 • 12 citations

Aeration of concentrated activated sludge

1966 • 12 citations

Optimal Design of Sequence of Continuous-Flow Stirred-Tank Reactors with Product Recycle

1965 • 12 citations

The action of drugs on Aerobacter aerogenes in various systems of continuous culture

1967 • 12 citations

STUDIES ON THE BIOLOGICAL STABILIZATION OF THIN STILLAGE: I. AEROBIC FERMENTATION

1965 • 12 citations

Development of a cross‐flow fermentation process with special reference to chlortetracycline production

1966 • 12 citations

Mass Culture of Microalgae for Photosynthetic Gas Exchange

1964 • 12 citations

THE INFLUENCE OF OXYGEN ON THE FORMATION OF NITRATASE IN PSEUDOMONAS DENITRIFICANS

1961 • 12 citations

FERMENTATION OF SULPHITE WASTE LIQUOR TO PRODUCE ORGANIC ACIDS

1961 • 12 citations

Continuous Culture of Rumen Bacteria

1963 • 11 citations

Die Assimilation von Glucose, Xylose und Essigsäure durch Candida utilis

1966 • 11 citations

Continuous Culture of Ruminal Microorganisms in Chemically Defined Medium

1962 • 11 citations

Adaptation of yeasts and bacteria to antimicrobial substances during continuous-flow cultivation

1960 • 11 citations

Gas Exchange of Algae

1965 • 11 citations

Chemostatic Concentrated Cultures of Heteroploid Mammalian Cell Suspensions in Dialyzing Fermentors

1965 • 11 citations

Continuous Microbiological Transformation of Steroids

1961 • 11 citations

CONTINUOUS BREWING IV. CONTINUOUS FERMENTATION ON THE PILOT SCALE

1962 • 11 citations

Carbon balance in high rate dissimilation of acetic acid in semicontinuous methane fermentation

1962 • 11 citations

NEW SYSTEMS OF CONTINUOUS FERMENTATION BY YEAST

1967 • 11 citations

Heat-Labile Antigens ofSalmonella enteritidisI. Extraction of Antigens

1966 • 10 citations

STUDIES ON CONTINUOUS FERMENTATION PART 1.

1965 • 10 citations

MUTATION IN CONTINUOUS CULTURES III

1964 • 10 citations

A model of a growing steady state system

1966 • 10 citations

The metabolism of n-decane by a Pseudomonas

1967 • 10 citations

Régulations métaboliques de la biosynthèse de la méthionine et de la thréonine chez Saccharomyces cerevisiae

1964 • 10 citations

An application of adaptive control to a continuous stirred tank reactor

1965 • 10 citations

AUTOMATED MICROBIOLOGICAL ASSAYS FOR NEOMYCIN IN PHARMACEUTICAL PRODUCTS

1965 • 10 citations

Der Brechungsindex vonAerobacter cloacae in kontinuierlicher und diskontinuierlicher Kultur

1965 • 10 citations

Gas monitor and control unit for cell culture system

1966 • 10 citations

INFLUENCE OF AERATION ON PRODUCTION OF BEER BY CONTINUOUS FERMENTATION

1961 • 10 citations

Continuous hydroxylation of progesterone byAspergillus ochraceus

1961 • 10 citations

OCCURRENCE OF β-GALACTOSIDASE IN THE GENUS SHIGELLA

1960 • 10 citations

GROWTH OF YEAST DURING CONTINUOUS FERMENTATION OF WORT

1962 • 9 citations

Dynamics of Class of Nonlinear, Distributed-Parameter, Chemical Reactors

1965 • 9 citations

Volatile sludge accumulation in activated sludge plants

1965 • 9 citations

On the stability of a continuous flow stirred‐tank reactor

1966 • 9 citations

Dynamic Aspects of Growth and Metabolism in Candida Utilis

1966 • 9 citations

Over‐All Light Energy Conversion Efficiency of a High‐Temperature Strain of Chlorella pyrenoidosa

1962 • 9 citations

The Use of Photosynthesis in the Control of Enclosed Environments

1962 • 9 citations

APPLICATION OF MATHEMATICAL ANALYSIS FOR THE CONTROL OF FERMENTATION PROCESSES

1966 • 9 citations

A uniform system of basic symbols for continuous cultivation of microorganisms

1963 • 9 citations

KINETICS OF BIOLOGICAL PROCESSES AS A BASIS OF AUTOMATIC REGULATION

1966 • 9 citations

Continuous culture experiments with saccharomyces rouxii

1960 • 9 citations

Measurement of the kinetics of biological systems at elevated temperatures utilizing flow techniques

1964 • 9 citations

Chapter 9 Continuous Synchronous Cultures of Protozoa

1964 • 8 citations

Effect of UV-Irradiated Nitrogen Gas on Biological Nitrogen Fixation in Continuous Cultures of Azotobacter vinelandii.

1963 • 8 citations

ACID-SOLUBLE SULFHYDRYL COMPOUNDS IN L-CELLS DURING VARIOUS CONDITIONS OF GROWTH

1966 • 8 citations

Laboratory Scale Activated Sludge Unit

1960 • 8 citations

Kinetik der Kompetenzentwicklung bei der genetischen Transformation von Bacillus subtilis

1966 • 8 citations

Continuous Synchronous Culture of Photosynthetic Micro-organisms

1967 • 8 citations

Control of Continuous-Flow Agitated-Tank Reactor

1965 • 8 citations

Growth-promoting Activity of Spent Sulfite Liquor for Sphaerotilus natans Growing in a Continuous-Flow Apparatus

1968 • 8 citations

A new microscale continuous-flow system for tissue culture

1963 • 8 citations

Die Milchsäuregärung von Lactobacterium delbrückii bei kontinuierlicher Kultivierung

1966 • 8 citations

Scale‐up of the activated sludge process

1966 • 8 citations

Effect of Growth Rate on the Production of Vitamin B₁₂-Active Substances by Soil Bacteria

1960 • 8 citations

Gas Exchange with Mass Cultures of Algae

1963 • 8 citations

A Bacteriophage-lysing Strain of Staphylococcus Employed in the Manufacture of Dry Sausage

1961 • 8 citations

Effect of Nitrogen Gas, Irradiated with a Beta-Ray Source, on Nitrogen Fixation in Continuous Cultures of Azotobacter vinelandii.

1963 • 8 citations

CONTINUOUS FERMENTATION IN RELATION TO YEAST METABOLISM

1968 • 8 citations

Kinetics of the steady-state bacterial culture. II. Variation in synthesis.

1966 • 7 citations

DNA turnover: Evidence from studies of steady-state bacterial populations

1964 • 7 citations

USE OF CONTINUOUS CULTURE METHOD FOR ANALYSING CELL FUNCTIONS

1964 • 7 citations

Experimental verification of the mathematical model for a continuous stirred‐tank reactor

1965 • 7 citations

Laboratory fermentors for submerged fermentation

1963 • 7 citations

Production of concentrated cell suspensions: The sponge fermentor

1961 • 7 citations

Bacterial sulfide production from sulfate‐enriched spent distillery liquor. III.

1964 • 7 citations

Factors affecting the degradation of ballast substances from citric acid production by sulphate-reducing bacteria

1961 • 7 citations

Fat Synthesis in Unicellular Algae

1958 • 7 citations

INTERACTION BETWEEN ESCHERICHIA COLI AND PSEUDOMONAS AERUGINOSA IN MIXED CULTURES

1965 • 7 citations

BREWING INDUSTRY RESEARCH FOUNDATION. COMPARISON OF THE COURSE OF FERMENTATION IN A CONTINUOUS AND A BATCH BREWING PROCESS

1961 • 7 citations

Virustat, a Device for Continuous Production of Viruses

1966 • 6 citations

STUDIES IN CONTINUOUS FERMENTATION I. EFFECTS OF YEAST CONCENTRATION

1966 • 6 citations

Continuous cultivation of microorganisms : proceedings of the second Symposium, held in Prague, June 18-23, 1962

1964 • 6 citations

A continuous fermentation technique for studying the kinetics of sugar uptake by baker's yeast

1966 • 6 citations

STUDIES ON CONTINUOUS FERMENTATION PART 2.

1965 • 6 citations

Detection of Positive and Negative Gas Ions in Ultraviolet Irradiated Nitrogen Gas and Their Effect on Nitrogen Fixation in Continuous Cultures of Azotobacter vinelandii.

1963 • 6 citations

THE POLAROGRAPHIC DETERMINATION OF OXYGEN UPTAKE AND TRANSFER RATE IN AEROBIC STEADY-STATE YEAST CULTIVATION ON LABORATORY AND PRODUCTION SCALE

1964 • 6 citations

Continuous culture: attitudes and myths.

1965 • 6 citations

Further simplification of a supernatant flow system for tissue culture

1961 • 6 citations

Adaptation ofEscherichia coli to chlortetracycline during continuous cultivation

1960 • 6 citations

Der Brechungsindex von Aerobacter cloacae in kontinuierlicher und diskontinuierlicher Kultur

1965 • 5 citations

Über das Gärvermögen der Hefen bei periodischen und kontinuierlichen Alkoholgärungen

1963 • 5 citations

Control Applications in Fermentation Processes

1960 • 5 citations

Über die Assimilation der in Melasseschlempe vorkommenden organischen Säuren

1966 • 5 citations

Filament formation during the continuous culture of aerobacter aerogenes in the presence of m-cresol

1967 • 5 citations

Yeast Morphology in Continuous Fermentation

1964 • 5 citations

Physiological characteristics of Escherichia coli in various states of balanced growth

1964 • 5 citations

STEADY-STATE ENRICHMENT CULTURES OF BACTERIA

1964 • 5 citations

FERMENTATIVE ABILITY OF YEASTS IN CONTINUOUS CULTURE

1966 • 5 citations

Continuous Production of Flor Sherry from New York State Wines1

1965 • 5 citations

Fermentation. Unit Processes Review

1961 • 5 citations

A note on the theory of uncatalysed linear expanding systems

1966 • 5 citations

Scale‐up from laboratory activated sludge and trickling filter units to prototype design

1966 • 5 citations

EFFECTS OF AERATION ON CONTINUOUS FERMENTATIONS OPERATING AT HIGH YEAST CONCENTRATIONS

1962 • 5 citations

A COMPARISON IN GUINEA PIGS OF BRUCELLA ABORTUS S.19 GROWN BY CONVENTIONAL AND CONTINUOUS METHODS

1962 • 4 citations

[A method of continuous cultivation of suspended animal cells in a flowing system].

1965 • 4 citations

Influence of the Aeration of Wort during Continuous Beer Fermentation

1965 • 4 citations

Growth Rate and Toxicity of Salmonella typhimurium

1965 • 4 citations

Einige prinzipielle Fragen der kontinuierlichen Fermentation

1965 • 4 citations

The adaptation ofCandida utilis to dense recycled molasses mashes under continuous cultivation

1966 • 4 citations

CULTIVATION OF SALMONELLA STRAINS IN CONTINUOUS CULTURE

1965 • 4 citations

THE PROPORTION OF STREPTOMYCIN-RESISTANT MUTANTS IN B. MEGATHERIUM CULTURES GROWING IN CONTINUOUS CULTURE

1964 • 4 citations

Effect of phosphate limitation on the senescence of glucose-and acetate-grown Escherichia coli.

1967 • 4 citations

Continuous culturing of algae in artificial illumination.

1965 • 4 citations

The industrial application of continuous culture.

1965 • 4 citations

Gas Exchange of Algae

1968 • 4 citations

Apparatus for the slow and continuous addition of clear sterile solutions

1961 • 4 citations

EFFECT OF BARLEY STEEP-LIQUOR ON FERMENTATION

1965 • 4 citations

THE INFLUENCE OF DISSOLVED OXYGEN ON FERMENTATION IN A SELECTED CONTINUOUS SYSTEM

1967 • 4 citations

Continuous culture of mixed populations.

1968 • 4 citations

The Kinetics of a Photosynthetic Gas Exchanger with Laminar Flow during Low Intensity Illumination

1967 • 4 citations

STUDIES ON THE CULTIVATION OF LISTERIA MONOCYTOGENES IN BATCH AND CONTINUOUS CULTURES

1967 • 4 citations

Production of fodder yeast from barley. 1. Preliminary studies on the use of the Waldhof fermentor.

1963 • 4 citations

Reproduction of batch growth curves in continuous culture

1964 • 3 citations

Input and volume distributions for continuous cultures

1968 • 3 citations

AUTOMATIC CONTROL OF MICROBIAL PROCESSES

1966 • 3 citations

London symposium of continuous culture of microorganisms

1960 • 3 citations

CONTINUOUS BREWING V. OPERATIONAL CHARACTERISTICS OF A PILOT-SCALE PLANT

1964 • 3 citations

Design and operation of a simple continuous‐culture apparatus

1966 • 3 citations

Factors Controlling the Production of Lysogenic Cultures of B. megatherium

1961 • 3 citations

[A mathematical description of the process of continuous cultivation of microalgae].

1965 • 3 citations

Dynamics in mycelial concentration of Aspergillus terreus K 26 in steady state of continuous culture (Proceedings of the U.S.Japan seminar on dynamics of microbial populations(特集))

1966 • 3 citations

[A new principle of regulating the composition of the medium in continuous cultivation of microorganisms].

1965 • 3 citations

BEHAVIOUR OF OIDIUM LACTIS IN CONTINUOUS CULTIVATION ON CARBOHYDRATES AND ON FATTY ACIDS

1964 • 3 citations

PHYSIOLOGICAL AND TECHNOLOGICAL PRINCIPLES OF GROWTH CONTROL OF MICROORGANISMS

1966 • 3 citations

NOTE ON THE ACCELERATION OF CONTINUOUS FERMENTATIONS BY MEANS OF YEAST AUTOLYSATES

1962 • 3 citations

Problems in Continuous Culture

1964 • 3 citations

Sewage sludge conditioning with sulphur oxidizing bacteria

1960 • 3 citations

Durchstr�mungsgef�� f�r Gewebekulturen

1959 • 3 citations

Efffect of aeration upon the continuous fermentation of wort.

1966 • 3 citations

[Semi-continuous biosynthesis of streptomycin and oxytetracycline].

1965 • 3 citations

FUNCTION OF SPECIFIC GROWTH-RATE CONSTANT IN CONTINUOUS FERMENTATION

1964 • 3 citations

Semi-continuous corrinoid biosynthesis by Propionibacterium petersonii.

1966 • 2 citations

Dynamics of Bacterial Growth and Fermentation in Continuous L-Glutamic Acid Fermentation

1966 • 2 citations

Untersuchungen über die Sorbosegärung in stationärer und kontinuierlicher Kultur

1966 • 2 citations

Some Characteristics of Trichosporon Cutaneum Propagation in Batch and Continuous Culture Systems in a Whey Substrate

1961 • 2 citations

USE OF CONTINUOUS CULTURES FOR ESTIMATING STRONTIUM SORPTION BY CHLORELLA PYRENOIDOSA.

1967 • 2 citations

Extinction probability of continuous culture.

1965 • 2 citations

[Unproportional flow cultivation of microorganisms].

1966 • 2 citations

Semikontinuální kvašení - stručný přehled výsledků z poloprovozních zkoušek.

1960 • 2 citations

The influence of lighting conditions and liquid depth on the growth activity of environmentally controlled algal cultures

1964 • 2 citations

An apparatus for continuous cultivation of micro-organisms with independent control of limiting growth factor and/or other metabolites.

1960 • 2 citations

Výroba biologicky aktívneho droždia polokontinuitným spôsobom.

1964 • 2 citations

Effects of pH and Substrate on Growth of Escherichia Coli and Pseudomonas Aeruginosa in Mixed Continuous Culture

1964 • 2 citations

Studies on Continuous Glutamic Acid Fermentation : (IV) Continuous Fermentation Using Four Fermentors in Series and Consideration on a Behavior of Growth Fermentor(Symposium on Biochemical Engineering-II"Sterilization and Cultural Engineering")

1965 • 2 citations

A distributed unstructured model(The dynamics of microbial growth-1-) (Proceedings of the U.S.Japan seminar on dynamics of microbial populations(特集))

1966 • 2 citations

A Laboratory Scale Apparatus for the Continuous Culture of Micro-Organisms with Automatic pH Control.

1959 • 2 citations

Growth in mixed cultures of microorganisms

1964 • 2 citations

Production of Seasoning Liquour for Sake by Continuous Fermentation

1963 • 2 citations

The inhibitory action of selenite on Escherichia coli, Proteus vulgaris and Salmonella thompson

1964 • 2 citations

Sulfate reduction by bacteria (Proceedings of the U.S.Japan seminar on dynamics of microbial populations(特集))

1966 • 2 citations

"Steady-state" competence for bacterial transformation

1968 • 1 citations

Continuous production of highly purified Clostridium tetani toxin.

1967 • 1 citations

Utilization of carboxymethyl cellulose (CMC) by a Pseudomonas atrofaciens mutant

1965 • 1 citations

Studien zur Lävansynthese

1963 • 1 citations

Výzkum a zavádění výroby krmných kvasnic kontinuální fermentací.

1963 • 1 citations

FOOD AND FODDER YEAST PRODUCTION FROM SULFITE WASTE LIQUOR

1958 • 1 citations

Deleted Work

1955 • 0 citations