Avian retrovirus integration protein: Structure-functional analysis of viable mutants

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

Nucleotide sequence of rous sarcoma virus

1983 • 901 citations

Mobile Genetic Elements

1984 • 574 citations

Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes.

1986 • 483 citations

New procedure for DNA transfection with polycation and dimethyl sulfoxide.

1984 • 481 citations

Correct integration of retroviral DNA in vitro

1987 • 459 citations

Genetic recombination

1989 • 373 citations

Standardized and simplified nomenclature for proteins common to all retroviruses

1988 • 336 citations

Construction and analysis of deletion mutations in the pol gene of moloney murine leukemia virus: A new viral function required for productive infection

1984 • 244 citations

EFFECTS OF SITE-SPECIFIC AMINO ACID MODIFICATION ON PROTEIN INTERACTIONS AND BIOLOGICAL FUNCTION

1985 • 224 citations

The DNA intermediate in yeast Ty1 element transposition copurifies with virus-like particles: Cell-free Ty1 transposition

1988 • 202 citations

Molecular Biology of RNA Tumor Viruses

1980 • 194 citations

A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration.

1984 • 182 citations

The retrovirus pol gene encodes a product required for DNA integration: identification of a retrovirus int locus.

1984 • 164 citations

Covalently closed circular DNA of avian sarcoma virus: Purification from nuclei of infected quail tumor cells and measurement by electron microscopy and gel electrophoresis

1976 • 136 citations

cis-Acting RNA packaging locus in the 115-nucleotide direct repeat of Rous sarcoma virus

1983 • 112 citations

Endonuclease activity of purified RNA-directed DNA polymerase from avian myeloblastosis virus.

1979 • 100 citations

Amino acid sequence homology applied to the prediction of protein secondary structures, and joint prediction with existing methods

1986 • 95 citations

A New Class of Endogenous Human Retroviral Genomes

1985 • 91 citations

Synthesis and processing of polymerase proteins of wild-type and mutant avian retroviruses

1980 • 79 citations

Virus-coded origin of a 32,000-dalton protein from avian retrovirus cores: structural relatedness of p32 and the beta polypeptide of the avian retrovirus DNA polymerase

1978 • 77 citations

Amino Acid Sequence Analysis of Reverse Transcriptase Subunits from Avian Myeloblastosis Virus

1980 • 68 citations

Sequence of the Long Terminal Repeat and Adjacent Segments of the Endogenous Avian Virus Rous-Associated Virus 0

1982 • 61 citations

Structural characterization of the avian retrovirus reverse transcriptase and endonuclease domains.

1985 • 60 citations

Requirement of the avian retrovirus pp32 DNA binding protein domain for replication

1984 • 59 citations

Properties of avian sarcoma-leukosis virus pp32-related pol-endonucleases produced in Escherichia coli

1988 • 55 citations

Studies on reverse transcriptase of RNA tumor viruses. I. Localization of thermolabile DNA polymerase and RNase H activities on one polypeptide

1975 • 55 citations

Genetic evidence that the avian retrovirus DNA endonuclease domain of pol is necessary for viral integration

1988 • 53 citations

Mechanism of Action of the Endonuclease Associated with the αβ and ββ Forms of Avian RNA Tumor Virus Reverse Transcriptase

1983 • 47 citations

Site-specific nicking at the avian retrovirus LTR circle junction by the viral pp32 DNA endonuclease

1985 • 45 citations

Analysis of mutant Moloney murine leukemia viruses containing linker insertion mutations in the 3' region of pol

1988 • 39 citations

Virus-coded DNA endonuclease from avian retrovirus

1981 • 34 citations

The β subunit of the DNA polymerase of avian sarcoma virus strain B77 is a phosphoprotein

1977 • 29 citations

Characterization of “early” temperature-sensitive mutants of avian sarcoma viruses: Biological properties, thermolability of reverse transcriptase in vitro, and synthesis of viral DNA in infected cells

1976 • 26 citations

Partial phosphorylation in vivo of the avian retrovirus pp32 DNA endonuclease

1980 • 25 citations

Secondary structural analysis of retrovirus integrase: Characterization by circular dichroism and empirical prediction methods

1989 • 21 citations

Avian retrovirus pp32 DNA endonuclease is phosphorylated on Ser in the carboxyl-terminal region

1988 • 15 citations

Mutants of the Rous sarcoma virus reverse transcriptase gene are nondefective in early replication events.

1985 • 13 citations