Insulin degradation. XIV. Interaction of insulin analogs, glucagon, growth hormone, vasopressin, oxytocin, and scrambled forms of ribonuclease and lysozyme with glutathione-insulin transhydrogenase (thiol:protein-disulfide oxidoreductase). Dependence upon conformation

Tissue sulfhydryl groups

1959 • 25,130 citations

The Preparation and Enzymatic Hydrolysis of Reduced and S-Carboxymethylated Proteins

1963 • 2,600 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆II. Inhibition: Nomenclature and theory

1963 • 865 citations

STUDIES ON THE GROSS STRUCTURE, CROSS-LINKAGES, AND TERMINAL SEQUENCES IN RIBONUCLEASE

1954 • 427 citations

A procedure for measurement of distribution spaces in isolated fat cells

1972 • 366 citations

Glucagon Physiology and Pathophysiology

1971 • 266 citations

Size heterogeneity of immunoreactive human ACTH in plasma and in extracts of pituitary glands and ACTH-producing thymoma

1971 • 186 citations

The spontaneous reoxidation of reduced beef and rat proinsulins.

1968 • 152 citations

DIVISION OF BIOCHEMISTRY: EVIDENCE FOR A PRECURSOR IN THE BIOSYNTHESIS OF INSULIN*

1967 • 134 citations

Large Glucagon Immunoreactivity in Extracts of Pancreas

1970 • 104 citations

Mode of Action of an Insulin-degrading Enzyme from Beef Liver

1962 • 93 citations

Studies on the Specificity and Mechanism of Action of Hepatic Glutathione-Insulin Transhydrogenase

1966 • 77 citations

Insulin degradation. II. The widespread distribution of glutathione-insulin transhydrogenase in the tissues of the rat.

1972 • 75 citations

Further Studies on the Properties of Hepatic Glutathione-Insulin Transhydrogenase

1963 • 67 citations

Insulin degradation V. Unmasking of glutathione-insulin transhydrogenase in rat liver microsomal membrane

1973 • 66 citations

Glutathione-Insulin Transhydrogenase of Human Liver

1965 • 61 citations

Sequential Degradation of Insulin by Rat Liver Homogenates

1972 • 56 citations

Insulin degradation X. Identification of insulin degrading activity of rat liver plasma membrane as glutathione-insulin transhydrogenase

1973 • 51 citations

Insulin degradation

1973 • 49 citations

Purification and properties of pancreatic glutathione-insulin transhydrogenase

1966 • 47 citations

A convenient preparation of reduced and S-sulfonated A and B chains of insulin☆

1966 • 45 citations

Insulin Degradation: VI. Feedback Control by Insulin of Liver Glutathione-Insulin Transhydrogenase in Rat

1974 • 44 citations

The identity of the insulin degrading thiol‐protein disulfide oxidoreductase (glutathione—insulin transhydrogenase) with the sulfhydryl‐disulfide interchange enzyme

1973 • 41 citations

Insulin degradation VII. Sequential degradation of insulin by rat liver homogenates at physiologic concentrations of insulin and in the absence of exogenous glutathione

1973 • 31 citations

Physical and biological properties of guinea pig insulin

1972 • 31 citations

Mode of action of glutathione-insulin transhydrogenase. Studies on the precipitate producted by its action on insulin

1966 • 28 citations

Insulin degradation

1974 • 24 citations

Enzymatic destruction of immunoreactivity in proinsulin and insulin and activation of their scrambled forms

1970 • 22 citations

Insulin degradation VIII. Protein thiols as co-substrates for glutathione- insulin transhydrogenase

1973 • 18 citations

Acceleration of regeneration of insulin activity from its inactive reduced A and B chains by pancreatic glutathioneinsulin transhydrogenase

1967 • 18 citations

Circular dichroic and immunologic studies of structure relations of insulin and derivatives

1973 • 14 citations

Insulin degradation in insulinoma: Evidence for the occurrence of an inactive form of glutathione-insulin transhydrogenase and for the absence of insulin A and B chains degrading protease(s)

1974 • 13 citations