Unusual interactions of excitatory amino acid receptor agonists: α- and β-kainate antagonize motor responses to N-methyl-d-aspartate in rodents

A simplified method of evaluating dose-effect experiments.

1948 • 7,047 citations

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

1984 • 2,822 citations

Excitatory Amino Acid Transmitters

1981 • 2,488 citations

Chronic catheterization of the spinal subarachnoid space

1976 • 2,244 citations

GABA‐Benzodiazepine‐Barbiturate Receptor Interactions

1981 • 910 citations

Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors

1984 • 824 citations

Anticonvulsant Action of Excitatory Amino Acid Antagonists

1982 • 692 citations

Possible Therapeutic Applications of Antagonists of Excitatory Amino acid Neurotransmitters

1985 • 558 citations

Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord

1982 • 302 citations

Mixed‐agonist action of excitatory amino acids on mouse spinal cord neurones under voltage clamp.

1984 • 274 citations

Selective association of N-methyl aspartate and quisqualate types of L-glutamate receptor with brain postsynaptic densities.

1984 • 238 citations

EXCITATORY AMINOACID ANTAGONISTS PROVIDE A THERAPEUTIC APPROACH TO NEUROLOGICAL DISORDERS

1985 • 217 citations

Quisqualate and L-glutamate inhibit retinal horizontal-cell responses to kainate.

1985 • 152 citations

The actions of excitatory amino acids on motoneurones in the feline spinal cord.

1979 • 147 citations

Excitatory amino acids and central synaptic transmission

1984 • 139 citations

Excitatory Amino Acids

1986 • 135 citations

Depressant actions of γ-d-glutamylaminomethyl sulfonate (GAMS) on amino acid-induced and synaptic excitation in the cat spinal cord

1985 • 113 citations

Muscle relaxant action of excitatory amino acid antagonists

1985 • 100 citations

Synaptic excitation in cultures of mouse spinal cord neurones: receptor pharmacology and behaviour of synaptic currents.

1986 • 98 citations

Structure-activity relations of dipeptide antagonists of excitatory amino acids

1984 • 88 citations

Anticonvulsant action of β-kainic acid in mice. Is β-kainic acid an N-methyl-d-aspartate antagonist?

1985 • 46 citations

Phosphono dipeptides and piperazine derivatives as antagonists of amino acid-induced and synaptic excitation in mammalian and amphibian spinal cord

1984 • 43 citations

Kainic acid derivatives with anticonvulsant activity

1984 • 33 citations

Anticonvulsant activity of two novel piperazine derivatives with potent kainate antagonist activity

1985 • 31 citations

Peptides derived from kainic acid as antagonists of N-methyl-d-aspartate-induced neuroexcitation in rat brain

1985 • 10 citations

β-Kainic acid is not an amino acid antagonist

1985 • 6 citations