Effects of the myosin inhibitor 2,3-butanedione monoxime on the physiology of fission yeast

Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae.

1984 • 838 citations

Order of events in the yeast secretory pathway

1981 • 804 citations

Phenotypic analysis of temperature-sensitive yeast actin mutants

1985 • 512 citations

The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesicles.

1991 • 471 citations

Growth in cell length in the fission yeast Schizosaccharomyces pombe

1985 • 466 citations

[76] β-d-Fructofuranoside fructohydrolase from yeast

1975 • 455 citations

Myosin Drives Retrograde F-Actin Flow in Neuronal Growth Cones

1996 • 403 citations

The Growing Fungus

1995 • 385 citations

Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane.

1994 • 370 citations

Actin and fimbrin are required for the internalization step of endocytosis in yeast.

1993 • 346 citations

The role of Myo2, a yeast class V myosin, in vesicular transport.

1995 • 324 citations

Myosin is involved in postmitotic cell spreading.

1995 • 306 citations

Experiments with fission yeast: A laboratory course manual

1994 • 290 citations

Localization of F-actin through the cell division cycle of Schizosaccharomyces pombe

1985 • 280 citations

Movement of yeast cortical actin cytoskeleton visualized in vivo.

1996 • 279 citations

Cell Wall Synthesis in Apical Hyphal Growth

1986 • 254 citations

Participation of myosin in gliding motility and host cell invasion by Toxoplasma gondii

1997 • 230 citations

Synthetic lethality screen identifies a novel yeast myosin I gene (MYO5): myosin I proteins are required for polarization of the actin cytoskeleton.

1996 • 229 citations

Movement of cortical actin patches in yeast.

1996 • 222 citations

Butanedione Monoxime Suppresses Contraction and ATPase Activity of Rabbit Skeletal Muscle1

1989 • 217 citations

Nuclear Pore Complex Number and Distribution throughout theSaccharomyces cerevisiaeCell Cycle by Three-Dimensional Reconstruction from Electron Micrographs of Nuclear Envelopes

1997 • 217 citations

Growth Polarity And Cytokinesis In Fission Yeast: The Role Of The Cytoskeleton

1986 • 216 citations

Type II Myosin Heavy Chain Encoded by the myo2 Gene Composes the Contractile Ring during Cytokinesis in Schizosaccharomyces pombe

1997 • 209 citations

Epistatic gene interactions in the control of division in fission yeast

1979 • 208 citations

Effect of 2,3-butanedione monoxime on myosin and myofibrillar ATPases. An example of an uncompetitive inhibitor

1992 • 206 citations

Actin and myosin function in directed vacuole movement during cell division in Saccharomyces cerevisiae.

1996 • 203 citations

myoA of Aspergillus nidulans encodes an essential myosin I required for secretion and polarized growth.

1995 • 201 citations

Myosin II Is Involved in the Production of Constitutive Transport Vesicles from the TGN

1997 • 184 citations

Tip Growth In Plant and Fungal Cells

1990 • 179 citations

Paralysis of skeletal muscle by butanedione monoxime, a chemical phosphatase

1988 • 171 citations

Localization of a myosin‐like protein to plasmodesmata

1998 • 166 citations

Schizosaccharomyces pombe cdc4+ gene encodes a novel EF-hand protein essential for cytokinesis.

1995 • 164 citations

Identification of a Second Myosin-II inSchizosaccharomyces pombe:

1997 • 161 citations

The Roles of Actin in Tip Growth of Fungi

1990 • 158 citations

Mechanism of action of 2, 3-butanedione 2-monoxime on contraction of frog skeletal muscle fibres

1988 • 135 citations

Fungal walls and hyphal growth.

1979 • 129 citations

The influence of 2,3-butanedione 2-monoxime (BDM) on the interaction between actin and myosin in solution and in skinned muscle fibres

1994 • 116 citations

Type II myosin involved in cytokinesis in the fission yeast,Schizosaccharomyces pombe

1997 • 109 citations

Myosin II is associated with Golgi membranes: identification of p200 as nonmuscle myosin II on Golgi-derived vesicles

1997 • 102 citations

A Marine Natural Product Inhibitor of Kinesin Motors

1998 • 100 citations

The organization of tip-growth-related organelles and microtubules revealed by quantitative analysis of freeze-substituted oomycete hyphae

1989 • 99 citations

Stimulation of radial expansion in arabidopsis roots by inhibitors of actomyosin and vesicle secretion but not by various inhibitors of metabolism

1995 • 88 citations

Organelle movements in the wild type and wall-less fz;sg;os-1 mutants of Neurospora Crassa are mediated by cytoplasmic microtubules

1993 • 85 citations

Identification of Myo3, a second type‐II myosin heavy chain in the fission yeast Schizosaccharomyces pombe

1997 • 81 citations

Reversible blockade of gap junctional communication by 2,3-butanedione monoxime in rat cardiac myocytes

1997 • 77 citations

Dynamics of contacts between lamellae of fibroblasts: Essential role of the actin cytoskeleton

1998 • 73 citations

The effects of antimicrotubule agents on organelle positioning in the cowpea rust fungus,Uromyces phaseoli var.vignae

1982 • 72 citations

Mitochondria and nuclei move by different mechanisms in Aspergillus nidulans.

1985 • 70 citations

Distribution of tubulin and actin through the cell division cycle of the fission yeast Schizosaccharomyces japonicus var. Versatilis: a comparison with Schizosaccharomyces pombe

1990 • 65 citations

Muscle cross-bridges bound to actin are disordered in the presence of 2,3-butanedione monoxime

1995 • 57 citations

Tip Growth and Polarity

1995 • 57 citations

Organelle Transport and Molecular Motors in Fungi

1998 • 54 citations

Novel suppression of an L‐type calcium channel in neurones of murine dorsal root ganglia by 2,3‐butanedione monoxime.

1992 • 52 citations

Myosin functions inXenopus retinal ganglion cell growth cone motilityin vivo

1997 • 51 citations

Myosin heavy chain turnover in cultured neonatal rat heart cells: effects of [Ca2+]i and contractile activity

1996 • 49 citations

Stacking of Golgi cisternae in Schizosaccharomyces pombe requires intact microtubules

1993 • 49 citations

Butanedione Monoxime Promotes Voltage-dependent Inactivation ofL-Type Calcium Channels in Heart. Effects on Gating Currents

1997 • 46 citations

Genetic analysis of resistant mutants to antimitotic benzimidazole compounds in Schizosaccharomyces pombe

1980 • 42 citations

Cytoskeleton interactions in the ascus development and sporulation of Sordaria macrospora

1993 • 41 citations

Enzymology of Tip Growth in Fungi

1990 • 41 citations

Cell Cycle Specificity of Certain Antimicrotubular Drugs in Schizosaccharomyces pombe

1982 • 40 citations

Dual action of 2,3-butanedione monoxime (BDM) on K+ current in human T lymphocytes.

1992 • 35 citations

Requirement of S. pombe exonuclease II, a homologue of S. cerevisiae Sep1, for normal mitotic growth and viability

1996 • 34 citations

Effects of 2,3-butanedione monoxime on contraction of frog skeletal muscles: An X-ray diffraction study

1992 • 34 citations

Effects of 2,3‐butanedione monoxime (BDM) on calcium channels expressed in Xenopus oocytes

1998 • 31 citations

Isolation, Properties, Function, and Regulation of Endo-(1 → 3)-β-Glucanases in Schizosaccharomyces pombe

1981 • 30 citations

2,3-Butanedione 2-Monoxime (BDM) Induces Calcium Release from Canine Cardiac Sarcoplasmic Reticulum

1996 • 28 citations

Block of ATP‐sensitive K⁺ channels in isolated mouse pancreatic β‐cells by 2,3‐butanedione monoxime

1994 • 28 citations

2,3-Butanedione monoxime blockade of Ca2+ currents in adult rat sympathetic neurons does not involve ‘chemical phosphatase’ activity

1993 • 26 citations

2,3-Butanedione monoxime modifies the glycine-gated chloride current of acutely isolated murine hypothalamic neurons

1996 • 23 citations

2,3-Butanedione monoxime (BDM) inhibition of delayed rectifier DRK1 (Kv2.1) potassium channels expressed in Xenopus oocytes.

1993 • 23 citations

Yeast myosin II: A new subclass of unconventional conventional myosins?

1998 • 22 citations

Effect of cytochalasin A on actin distribution in the fission yeastSchizosaccharomyces pombe studied by fluorescent and electron microscopy

1993 • 21 citations

The effect of 2,3-butanedione 2-monoxime (BDM) on ventricular trabeculae from the avian heart

1995 • 19 citations

Septum formation inAspergillus nidulans

1995 • 19 citations

Effects of 2,3-butanedione monoxime on blood pressure, myocardial Ca2+ currents, and action potentials of rats⊃

1995 • 16 citations

Inhibition of Cloned Human L-Type Cardiac Calcium Channels by 2,3-Butanedione Monoxime Does Not Require PKA-Dependent Phosphorylation Sites

1997 • 14 citations

Potentiation of sarcoplasmic reticulum Ca2+ release by 2,3-butanedione monoxime in crustacean muscle

1993 • 13 citations

Effects of Butanedione Monoxime and Temperature on Prolonged Cardiac Storage

1997 • 6 citations