The psychopharmacology of astroglial cells

Multiple receptors for dopamine

1979 • 3,739 citations

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

1976 • 2,224 citations

Effect of Chlorpromazine or Haloperidol on Formation of 3‐Methoxytyramine and Normetanephrine in Mouse Brain

1963 • 2,148 citations

Benzodiazepine Receptor: Demonstration in the Central Nervous System

1977 • 1,705 citations

Antipsychotic drug doses and neuroleptic/dopamine receptors

1976 • 1,623 citations

Benzodiazepine receptors in rat brain

1977 • 1,459 citations

Fine structural localization of glutamine synthetase in astrocytes of rat brain

1979 • 1,318 citations

Reticular formation of the brain

1959 • 1,213 citations

Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the “dopamine receptor”

1972 • 1,022 citations

Phosphorylated Proteins as Physiological Effectors

1978 • 975 citations

Pharmacological studies on presynaptic inhibition

1963 • 765 citations

Brain receptors for antipsychotic drugs and dopamine: direct binding assays.

1975 • 695 citations

Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat

1971 • 685 citations

Dopamine ?Autoreceptors?: Pharmacological characterization by microiontophoretic single cell recording studies

1977 • 544 citations

Dopamine Receptors in the Brain

1975 • 528 citations

In vitro studies on central and peripheral monoamine neurons at the ultrastructural level

1968 • 499 citations

GLIA IN THE LEECH CENTRAL NERVOUS SYSTEM: PHYSIOLOGICAL PROPERTIES AND NEURON-GLIA RELATIONSHIP

1964 • 482 citations

Glial Cell Function: Uptake of Transmitter Substances

1971 • 460 citations

Dopamine-Sensitive Adenylate Cyclase in Mammalian Brain: A Possible Site of Action of Antipsychotic Drugs

1974 • 450 citations

High densities of benzodiazepine receptors in human cortical areas

1977 • 406 citations

Noradrenergic axon terminals in the cerebral cortex of rat. III. Topometric ultrastructural analysis

1977 • 396 citations

Anesthesia and the responsiveness of individual neurons of the caudate nucleus of the cat to acetylcholine, norepinephrine and dopamine administered by microelectrophoresis.

1965 • 395 citations

Dopamine receptor binding: Differentiation of agonist and antagonist states with 3H-dopamine and 3H-haloperidol

1975 • 390 citations

Dynamic properties of glia cells

1979 • 344 citations

Serotonin axons in the supra- and subependymal plexuses and in the leptomeninges; Their roles in local alterations of cerebrospinal fluid and vasomotor activity

1976 • 327 citations

Chlordiazepoxide selectively augments GABA action in spinal cord cell cultures

1977 • 280 citations

On the Role of Glial Cells in the Mammalian Nervous System

1974 • 277 citations

Benzodiazepines specifically modulate GABA-mediated postsynaptic inhibition in cultured mammalian neurones

1978 • 276 citations

The role of cyclic nucleotides in central synaptic function

1975 • 263 citations

Uptake of the neurotransmitter candidate glutamate by glia

1974 • 247 citations

The characterisation of [3H]GABA uptake into the satellite glial cells of rat sensory ganglia

1974 • 246 citations

Effect of Catecholamines on the Adenosine 3′:5′-Cyclic Monophosphate Concentrations of Clonal Satellite Cells of Neurons

1971 • 245 citations

The Action of Neuroleptic Drugs on Dopamine-Stimulated Adenosine Cyclic 3',5'-Monophosphate Production in Rat Neostriatum and Limbic Forebrain

1974 • 240 citations

Glial cell function: Active control of extracellular K+ concentration

1972 • 233 citations

The effects of anaesthetics on synaptic excitation and inhibition in the olfactory bulb

1972 • 231 citations

Enhancement of Dopamine-Stimulated Adenylate Cyclase Activity in Rat Caudate after Lesions in Substantia Nigra: Evidence for Denervation Supersensitivity

1974 • 228 citations

Neuroglia: Biophysical Properties and Physiologic Function

1970 • 209 citations

Brain Specific Benzodiazepine Receptors

1978 • 205 citations

CHARACTERIZATION OF BENZODIAZEPINE BINDING SITES IN CULTURED CELLS OF NEURAL ORIGIN

1979 • 204 citations

Amino Acids as Chemical Transmitters

1978 • 197 citations

Nicotinamide is a brain constituent with benzodiazepine-like actions

1979 • 191 citations

Identification of inosine and hypoxanthine as endogenous inhibitors of [3H] diazepam binding in the central nervous system

1978 • 189 citations

Pharmacological evidence for GABA as the transmitter in granule cell inhibition in the olfactory bulb

1971 • 180 citations

The Role of Cyclic Nucleotides in Central Synaptic Function

1975 • 177 citations

Different Actions of Anticonvulsant and Anesthetic Barbiturates Revealed by Use of Cultured Mammalian Neurons

1978 • 175 citations

The Role of Cyclic Nucleotides in the CNS

1977 • 163 citations

Barbiturate inhibition of calcium uptake by depolarized nerve terminals in vitro.

1975 • 163 citations

γ-Aminobutyric Acid Uptake by Sympathetic Ganglia

1972 • 162 citations

Electrophysiological evidence for involvement of cyclic adenosine monophosphate in dopamine responses of caudate neurons

1974 • 162 citations

Molecular Mechanisms Mediating the Action of Diazepam on GABA Receptors

1978 • 161 citations

Comparison of the effects of neuroleptic drugs on pre- and postsynaptic dopaminergic mechanisms in the rat striatum.

1976 • 160 citations

Convergence of excitatory synaptic inputs to caudate spiny neurons

1977 • 159 citations

5-Hydroxydopamine ‘tagged’ neuronal boutons in rabbit neostriatum: interrelationship between vesicles and axonal membrane

1974 • 154 citations

Potassium-stimulated γ-aminobutyric acid release from neurons and glia

1977 • 154 citations

Benzodiazepine receptors: labeling in intact animals with [3H] flunitrazepam

1978 • 154 citations

Glial contamination of synaptosomal fractions

1976 • 146 citations

LOCALIZATION OF THE SITES OF γ-AMINOBUTYRIC ACID (GABA) UPTAKE IN LOBSTER NERVE-MUSCLE PREPARATIONS

1971 • 139 citations

GLUTAMATE UPTAKE BY A STIMULATED INSECT NERVE MUSCLE PREPARATION

1970 • 136 citations

Immunocytochemical localization, in synapses, of protein I, an endogenous substrate for protein kinases in mammalian brain.

1979 • 135 citations

Labelling of benzodiazepine receptors in vivo

1978 • 134 citations

Dopamine-Sensitive Adenylate Cyclase Occurs in a Region of Substantia Nigra Containing Dopaminergic Dendrites

1976 • 132 citations

Benzodiazepine and β-adrenergic receptor ligands independently stimulate phospholipid methylation

1979 • 128 citations

The pharmacology of inhibition of mitral cells in the olfactory bulb

1971 • 126 citations

Accumulation and disappearance of catecholamines formed from tyrosine-14C in mouse brain; effect of some psychotropic drugs

1968 • 117 citations

A MODIFIED PROCEDURE FOR ISOLATION OF ASTROCYTE‐ AND NEURON‐ENRICHED FRACTIONS FROM RAT BRAIN

1978 • 111 citations

REVERSAL OF THE ACTION OF AMINO ACID ANTAGONISTS BY BARBITURATES AND OTHER HYPNOTIC DRUGS

1978 • 105 citations

Antagonistic effects of apomorphine and haloperidol on rat striatal synaptosomal tyrosine hydroxylase

1974 • 105 citations

Anticonvulsant and anesthetic barbiturates

1979 • 104 citations

Antipsychotic Drugs and Dopamine-Stimulated Adenylate Cyclase Prepared from Corpus Striatum of Rat Brain

1974 • 102 citations

Multiple receptors for brain dopamine.

1978 • 86 citations

Possible relationship between glial cells, dopamine and the effects of antipsychotic drugs

1977 • 82 citations

Central Actions of Benzodiazepines: General Introduction

1978 • 82 citations

THE RESPIRATORY CHAIN

1970 • 76 citations

Benzodiazepines and central inhibitory mechanisms

1978 • 75 citations

Neurotransmission and glial cells: A functional relationship?

1976 • 73 citations

KINETICS OF ADENOSINE UPTAKE INTO ASTROCYTES

1978 • 68 citations

Barbiturates block calcium uptake by stimulated and potassium-depolarized rat sympathetic ganglia.

1976 • 68 citations

Cellular localization of [3H]-diazepam receptors

1978 • 67 citations

The effect of barbiturates on [3H]GABA transport in rat cerebral cortex slices

1974 • 67 citations

Evidence that benzodiazepine receptors reside on cerebellar purkinje cells: Studies with “nervous” mutant mice

1978 • 64 citations

Reduction in benzodiazepine receptors associated with Purkinje cell degeneration in ‘nervous’ mutant mice

1979 • 59 citations

Mediation by cyclic AMP of hormone-stimulated glycogenolysis in cultured rat astrocytoma cells

1972 • 58 citations

Competitive inhibition of benzodiazepine binding by fractions from porcine brain.

1978 • 55 citations

Cyclic Nucleotides, Protein Phosphorylation and Synaptic Function

1976 • 49 citations

High-affinity uptake of ?-aminobutyric acid in cultured glial and neuronal cells

1979 • 42 citations

Cerebral glycogenolysis and stimulation of β-adrenoreceptors and histamine H2 receptors

1975 • 41 citations

Phenobarbital actions in vivo: effects on extra cellular potassium activity and oxidative metabolism in cat cerebral cortex.

1977 • 36 citations

Effect of barbiturates on release of endogenous amino acids from rat cortex slices

1979 • 34 citations

Receptor studies on isolated astroglial cell fractions prepared with and without trypsin

1980 • 26 citations

Inhibition by barbiturates of an intense net uptake of potassium into astrocytes

1979 • 26 citations

Dopamine, a modulator of carbohydrate metabolism in the caudate nucleus

1977 • 23 citations

A study on the development of barbiturate tolerance and dependence in hamster glial cells in culture

1976 • 22 citations

Development and mechanism of barbiturate tolerance in glial cell cultures

1979 • 20 citations

Inhibition of γ-aminobutyric acid uptake into astrocytes by pentobarbital

1978 • 16 citations

EFFECT OF PENTOBARBITAL ON MITOCHONDRIAL SYNTHESIS IN CULTURED GLIAL CELLS

1979 • 14 citations

Preparation of glial plasma membrane from a cell fraction enriched in astrocytes

1976 • 10 citations

Phenobarbital effect on glial cell respiration in the presence of a high concentration of potassium

1978 • 9 citations

Effect of chronic pentobarbital treatment on high affinity uptake of L-glutamate by cultured glial cells

1978 • 5 citations

Localization of benzodiazepine receptors using a novel type of photoaffinity label

1979 • 5 citations

Interactions between Neurotransmitters and Astroglial Cells

1978 • 2 citations