CR3 (CD11b, CD18): a phagocyte and NK cell membrane receptor with multiple ligand specificities and functions

The role of membrane receptors for C3b and C3d in phagocytosis.

1977 • 536 citations

Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes.

1983 • 495 citations

Tumor-promoting phorbol esters stimulate C3b and C3b' receptor-mediated phagocytosis in cultured human monocytes.

1982 • 444 citations

Membrane complement receptor type three (CR3) has lectin-like properties analogous to bovine conglutinin as functions as a receptor for zymosan and rabbit erythrocytes as well as a receptor for iC3b.

1985 • 433 citations

Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide.

1986 • 415 citations

Phagocytosis of Legionella pneumophila is mediated by human monocyte complement receptors.

1987 • 287 citations

Cross-reaction of a rat-anti-mouse phagocyte-specific monoclonal antibody (anti-Mac-1) with human monocytes and natural killer cells.

1981 • 234 citations

Specificity of Membrane Complement Receptor Type Three (CR3) for ß-Glucans

1987 • 233 citations

A beta-glucan inhibitable receptor on human monocytes: its identity with the phagocytic receptor for particulate activators of the alternative complement pathway.

1985 • 216 citations

Phorbol esters cause sequential activation and deactivation of complement receptors on polymorphonuclear leukocytes.

1986 • 206 citations

Dissociation between increased surface expression of gp165/95 and homotypic neutrophil aggregation.

1988 • 156 citations

Development of functional complement receptors during in vitro maturation of human monocytes into macrophages.

1980 • 154 citations

Role of Binding Through C3b and IgG in Polymorphonuclear Neutrophil Function: Studies with Trypsin-Generated C3b

1979 • 150 citations

An immobile subset of plasma membrane CD11b/CD18 (Mac-1) is involved in phagocytosis of targets recognized by multiple receptors.

1989 • 141 citations

Interaction of target cell-bound C3bi and C3d with human lymphocyte receptors. Enhancement of antibody-mediated cellular cytotoxicity.

1981 • 109 citations

The function of human NK cells is enhanced by β‐glucan, a ligand of CR3 (CD11b/CD18)

1991 • 97 citations

Identification of the leukocyte adhesion molecules CD11 and CD18 as receptors for type 1-fimbriated (mannose-specific) Escherichia coli

1991 • 95 citations

Neutrophil aggregation is beta 2-integrin- and L-selectin-dependent in blood and isolated cells.

1992 • 90 citations

Role of Complement Receptor Type Three and Serum Opsonins in the Neutrophil Response to Yeast

1987 • 76 citations

The role of C3 fragments in endocytosis and extracellular cytotoxic reactions by polymorphonuclear leukocytes

1982 • 70 citations

Ligand-Receptor Interactions in the Phagocytosis of Virulent Streptococcus pneumoniae by Polymorphonuclear Leukocytes

1986 • 68 citations

Two pathways of CD11b/CD18-mediated neutrophil aggregation with different involvement of protein kinase C-dependent phosphorylation.

1990 • 67 citations

Staurosporine inhibits neutrophil phagocytosis but not iC3b binding mediated by CR3 (CD11b/CD18).

1991 • 47 citations

THE EMPLOYMENT OF GLUCAN AND GLUCAN ACTIVATED MACROPHAGES IN THE ENHANCEMENT OF HOST RESISTANCE TO MALIGNANCIES IN EXPERIMENTAL ANIMALS

1976 • 40 citations

Contribution of CR3, CD11b/CD 18 to cytolysis by human NK cells

1990 • 40 citations

Role of neutrophil receptors in opsonophagocytosis of coagulase-negative staphylococci

1991 • 36 citations

Induction of a beta-1,3-D-glucan receptor in P388D1 cells treated with retinoic acid or 1,25-dihydroxyvitamin D3.

1988 • 21 citations

THE IN VIVO DESTRUCTION OF HUMAN TUMOR BY GLUCAN ACTIVATED MACROPHAGES

1976 • 17 citations

The Role of C3 in Mediating Binding and Ingestion of Group B Streptococcus Serotype III by Murine Macrophages

1991 • 17 citations

Antigenic relationship between the alpha-chain of C3, a leucocyte-surface antigen involved in the activation of phagocytic cells, and a 50,000 MW B-cell antigen.

1985 • 13 citations