Tolerance induction by ‘megadose’ transplants of CD34+ stem cells: a new option for leukemia patients without an HLA-matched donor

Inhibition of death receptor signals by cellular FLIP

1997 • 2,577 citations

Treatment of High-Risk Acute Leukemia with T-Cell–Depleted Stem Cells from Related Donors with One Fully Mismatched HLA Haplotype

1998 • 1,200 citations

Role of Natural Killer Cell Alloreactivity in HLA-Mismatched Hematopoietic Stem Cell Transplantation

1999 • 993 citations

HYPOFERRÆMIA IN OBESE ADOLESCENTS

1962 • 650 citations

Successful engraftment of T-cell-depleted haploidentical "three-loci" incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to bone marrow inoculum

1994 • 590 citations

Transplantation for severe combined immunodeficiency with HLA-A,B,D,DR incompatible parental marrow cells fractionated by soybean agglutinin and sheep red blood cells

1983 • 497 citations

TRANSPLANTATION FOR ACUTE LEUKAEMIA WITH HLA-A AND B NONIDENTICAL PARENTAL MARROW CELLS FRACTIONATED WITH SOYBEAN AGGLUTININ AND SHEEP RED BLOOD CELLS

1981 • 385 citations

Monoclonal antibodies to promote marrow engraftment and tissue graft tolerance

1986 • 344 citations

Megadose of T cell-depleted bone marrow overcomes MHC barriers in sublethally irradiated mice

1995 • 340 citations

Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning

1997 • 317 citations

Phenotypic characterization of a novel bone marrow-derived cell that facilitates engraftment of allogeneic bone marrow stem cells

1994 • 298 citations

Karnofsky Memorial Lecture. Marrow transplantation for malignant diseases.

1983 • 275 citations

GRAFT REJECTION IN RECIPIENTS OF T-CELL-DEPLETED HLA-NONIDENTICAL MARROW TRANSPLANTS FOR LEUKEMIA

1987 • 241 citations

GRAFT REJECTION IN RECIPIENTS OF T-CELL-DEPLETED HLA-NONIDENTICAL MARROW TRANSPLANTS FOR LEUKEMIA

1987 • 220 citations

Development of immunity in human severe primary T cell deficiency following haploidentical bone marrow stem cell transplantation.

1986 • 199 citations

Programmed Cell Death of T Cells Signaled by the T Cell Receptor and the α₃Domain of Class I MH

1991 • 196 citations

TOLERANCE INDUCTION BY "MEGADOSE" HEMATOPOIETIC TRANSPLANTS

1998 • 184 citations

Marrow Transplantation for Malignant Disease

1987 • 171 citations

GRAFT REJECTION AND GRAFT-VERSUS-HOST DISEASE: MIRROR IMAGES

1986 • 128 citations

A correlation between conditioning and engraftment in recipients of MHC-mismatched T cell-depleted murine bone marrow transplants.

1985 • 113 citations

Transplantation of Megadoses of Purified Haploidentical Stem Cells

1999 • 112 citations

Enhancement by dimethyl myleran of donor type chimerism in murine recipients of bone marrow allografts

1989 • 107 citations

IMMUNORECONSTITUTION IN SEVERE COMBINED IMMUNODEFICIENCY AFTER TRANSPLANTATION OF HLA-HAPLOIDENTICAL, T-CELL-DEPLETED BONE MARROW

1984 • 105 citations

Recipient immune-competent T lymphocytes can survive intensive conditioning for bone marrow transplantation

1986 • 93 citations

Demonstration of clonable alloreactive host T cells in a primate model for bone marrow transplantation.

1986 • 92 citations

Wheat germ agglutinin-positive cells in a stem cell-enriched fraction of mouse bone marrow have potent natural suppressor activity.

1988 • 84 citations

Enhancement of bone marrow allografts from nude mice into mismatched recipients by T cells void of graft-versus-host activity.

1990 • 83 citations

HLA-haploidentical bone marrow transplantation for severe combined immunodeficiency using E rosette fractionation and cyclosporine

1986 • 81 citations

Abrogation of bone marrow allograft resistance in mice by increased total body irradiation correlates with eradication of host clonable T cells and alloreactive cytotoxic precursors.

1987 • 80 citations

Clonal deletion of postthymic T cells: veto cells kill precursor cytotoxic T lymphocytes.

1992 • 74 citations

Cloned natural suppressor cells prevent lethal graft-vs-host disease.

1987 • 72 citations

Influence of cell dose and graft-versus-host reactivity on rejection rates after allogeneic bone marrow transplantation

1992 • 70 citations

Induction of Donor-Type Chimerism and Transplantation Tolerance Across Major Histocompatibility Barriers in Sublethally Irradiated Mice by Sca-1+Lin− Bone Marrow Progenitor Cells: Synergism With Non-Alloreactive (Host × Donor)F1 T Cells

1999 • 70 citations

Enhancement of T-cell-depleted bone marrow allografts in the absence of graft-versus-host disease is mediated by CD8+ CD4- and not by CD8- CD4+ thymocytes

1992 • 59 citations

Evaluation of HLA‐Haplotype Disparate Parental Marrow Grafts Depleted of T Lymphocytes by Differential Agglutination with a Soybean Lectin and E‐Rosette Depletion for the Treatment of Severe Combined Immunodeficiency¹

1986 • 56 citations

Total lymphoid irradiation to prevent graft rejection in recipients of HLA non-identical T cell-depleted allogeneic marrow.

1991 • 54 citations

The Facilitating Effect Of One-Dr Antigen Sharing In Renal Allograft Tolerance Induced By Donor Bone Marrow In Rhesus Monkeys

1995 • 53 citations

The role of donor lymphoid cells in allogeneic marrow engraftment.

1990 • 51 citations

Enhancement of T-cell-depleted bone marrow allografts in the absence of graft-versus-host disease is mediated by CD8+ CD4- and not by CD8- CD4+ thymocytes

1992 • 49 citations

The Facilitating Effect Of One-Dr Antigen Sharing In Renal Allograft Tolerance Induced By Donor Bone Marrow In Rhesus Monkeys

1995 • 48 citations

Bone marrow transplantation: Biological mechanisms and clinical practice

1985 • 44 citations

Bone Marrow Transplan- tation: Biological Mechanisms and Clinical Practice

1985 • 32 citations

DO DONOR CELLS FUNCTION AS VETO CELLS IN THE INDUCTION AND MAINTENANCE OF TOLERANCE ACROSS AN MHC DISPARITY IN MIXED LYMPHOID RADIATION CHIMERAS?

1993 • 29 citations

Veto-like down-regulation of T helper cell reactivity in vivo by injection of semi-allogeneic spleen cells

1991 • 28 citations

Functional Heterogeneity in Allospecific Cytotoxic T Lymphocyte Clones

1989 • 25 citations

Tolerance induction by megadose stem cell transplants: synergism between SCA-1+Lin− cells and nonalloreactive T cells

1998 • 21 citations

Thy 1+ donor cells function as veto cells in the maintenance of tolerance across a major histocompatibility complex disparity in mixed-lymphoid radiation chimeras.

1993 • 19 citations

What can be done to prevent graft versus host disease?

1994 • 16 citations