A pharmacokinetic model for high-dose methotrexate infusions in man

Methotrexate Pharmacokinetics

1971 • 481 citations

The Routine Fitting of Kinetic Data to Models

1962 • 336 citations

7-Hydroxymethotrexate as a urinary metabolite in human subjects and rhesus monkeys receiving high dose methotrexate.

1976 • 256 citations

Some Formal Approaches to the Analysis of Kinetic Data in Terms of Linear Compartmental Systems

1962 • 169 citations

Pharmacokinetics of methotrexate

1974 • 158 citations

Improved therapeutic index of methotrexate with "leucovorin rescue".

1973 • 148 citations

Pharmacokinetics of methotrexate

1973 • 125 citations

Methotrexate therapy of head and neck cancer: improvement in therapeutic index by the use of leucovorin "rescue".

1970 • 110 citations

Kinetic model for the disposition and metabolism of moderate and high-dose methotrexate (NSC-740) in man.

1975 • 52 citations

Comparative studies on the transport of aminopterin, methotrexate, and methasquin by the L1210 leukemia cell.

1972 • 50 citations

Clinical trials and pharmacokinetics of intermittent high-dose methotrexate-"leucovorin rescue" for children with malignant tumors.

1974 • 45 citations

Methotrexate Tissue Distribution: Prediction by a Mathematical Model<xref ref-type="fn" rid="FN2">2</xref>

1971 • 36 citations

The kinetics of methotrexate distribution in spontaneous canine lymphosarcoma

1975 • 28 citations

Radioimmunoassay for methotrexate.

1974 • 23 citations

Progress report on high-dose methotrexate (NSC-740) with citrovorum rescue in the treatment of metastatic bone tumors.

1974 • 20 citations