Functional CD40 ligand expression on T lymphocytes in the absence of T cell receptor engagement: involvement in interleukin‐2‐induced interleukin‐12 and interferon‐γ production

Interleukin-12: A Proinflammatory Cytokine with Immunoregulatory Functions that Bridge Innate Resistance and Antigen-Specific Adaptive Immunity

1995 • 2,437 citations

The CD40 Antigen and its Ligand

1994 • 1,259 citations

Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells.

1992 • 1,168 citations

Molecular and biological characterization of a murine ligand for CD40

1992 • 1,029 citations

Induction of human IgE synthesis in B cells by mast cells and basophils

1993 • 662 citations

CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40.

1993 • 593 citations

Humoral immune responses in CD40 ligand-deficient mice.

1994 • 541 citations

gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory.

1994 • 431 citations

Activated T cells induce interleukin‐12 production by monocytes via CD40‐CD40 ligand interaction

1995 • 427 citations

Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion.

1992 • 409 citations

The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells.

1993 • 384 citations

Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells.

1994 • 367 citations

Regulation of interleukin-12 expression in human monocytes: selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes

1995 • 341 citations

Activated human T cells express a ligand for the human B cell‐associated antigen CD40 which participates in T cell‐dependent activation of B lymphocytes

1992 • 323 citations

IL-12 receptor. II. Distribution and regulation of receptor expression.

1992 • 298 citations

Mechanisms of IFN-gamma induction by natural killer cell stimulatory factor (NKSF/IL-12). Role of transcription and mRNA stability in the synergistic interaction between NKSF and IL-2.

1992 • 284 citations

IL-13 induces proliferation and differentiation of human B cells activated by the CD40 ligand

1993 • 260 citations

CD40 ligand and its role in X-linked hyper-IgM syndrome

1993 • 257 citations

A comparative study of IL-12 (cytotoxic lymphocyte maturation factor)-, IL-2-, and IL-7-induced effects on immunomagnetically purified CD56+ NK cells.

1992 • 245 citations

The CD40 ligand expressed by human B cells costimulates B cell responses.

1995 • 200 citations

Learning from lesions: patterns of tissue inflammation in leprosy.

1988 • 199 citations

Molecular interactions mediating T-B lymphocyte collaboration in human lymphoid follicles. Roles of T cell-B-cell-activating molecule (5c8 antigen) and CD40 in contact-dependent help.

1992 • 194 citations

Role of the CD40‐CD40 ligand interaction in CD4⁺ T cell contact‐dependent activation of monocyte interleukin‐1 synthesis

1994 • 174 citations

High frequency of cross-reactive cytotoxic T lymphocytes elicited during the virus-induced polyclonal cytotoxic T lymphocyte response.

1993 • 160 citations

Soluble forms of CD40 inhibit biologic responses of human B cells.

1992 • 154 citations

CD40 ligand is functionally expressed on human eosinophils

1995 • 149 citations

CD40 ligand is required for resolution of Pneumocystis carinii pneumonia in mice.

1995 • 133 citations

Activated T cells enhance nitric oxide production by murine splenic macrophages through gp39 and LFA‐1

1995 • 132 citations

CD2 is involved in maintenance and reversal of human alloantigen-specific clonal anergy.

1994 • 119 citations

Soluble CD23 directly activates monocytes to contribute to the antigen-independent stimulation of resting T cells.

1995 • 91 citations

CD2 regulates responsiveness of activated T cells to interleukin 12.

1995 • 87 citations

In vivo regulation of macrophage IL-12 production during type 1 and type 2 cytokine-mediated granuloma formation.

1995 • 79 citations

Regulation of cytokine production by soluble CD23: costimulation of interferon gamma secretion and triggering of tumor necrosis factor alpha release.

1994 • 67 citations

Expression of a 32‐kDa ligand for the CD40 antigen on activated human T lymphocytes

1993 • 65 citations

Helper effector function of human T cells stimulated by anti‐CD3 mAb can be enhanced by co‐stimulatory signals and is partially dependent on CD40‐CD40 ligand interaction

1994 • 47 citations

Monocyte-regulated IFN-gamma production in human T cells involves CD2 signaling.

1993 • 43 citations

Differential expression of CD40 ligand on T cell subsets. Implications for different roles of CD45RA+ and CD45RO+ cells in IgE production.

1996 • 19 citations

Regulatory effect of interleukin-4 (IL-4) on the expression and function of lymphocyte adhesion receptors involved in IL-2-induced cell aggregation.

1993 • 6 citations