Newly expressed progesterone receptor cannot activate stable, replicated mouse mammary tumor virus templates but acquires transactivation potential upon continuous expression.

Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells

1984 • 1,416 citations

Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter.

1987 • 597 citations

Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription

1992 • 596 citations

Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors

1992 • 477 citations

Removal of positioned nucleosomes from the yeast PHO5 promoter upon PHO5 induction releases additional upstream activating DNA elements.

1986 • 470 citations

Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element

1984 • 449 citations

Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo

1987 • 448 citations

Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter

1990 • 440 citations

Transcription Factor Loading on the MMTV Promoter: A Bimodal Mechanism for Promoter Activation

1992 • 411 citations

The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction.

1986 • 406 citations

Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter.

1991 • 372 citations

Glucocorticoid and progesterone receptors bind to the same sites in two hormonally regulated promoters

1985 • 366 citations

Mechanisms of nuclear localization of the progesterone receptor: Evidence for interaction between monomers

1989 • 329 citations

Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor.

1990 • 292 citations

The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region.

1987 • 275 citations

In vivo footprinting of rat TAT gene: Dynamic interplay between the glucocorticoid receptor and a liver-specific factor

1991 • 270 citations

Facilitated binding of GAL4 and heat shock factor to nucleosomal templates: differential function of DNA-binding domains.

1991 • 269 citations

Signal transduction by steroid hormones: nuclear localization is differentially regulated in estrogen and glucocorticoid receptors.

1990 • 257 citations

Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomes

1991 • 242 citations

The transcriptionally-active MMTV promoter is depleted of histone H1

1992 • 222 citations

Glucocorticoids are required for establishment and maintenance of an alteration in chromatin structure: induction leads to a reversible disruption of nucleosomes over an enhancer.

1991 • 206 citations

The dose dependence of glucocorticoid-inducible gene expression results from changes in the number of transcriptionally active templates.

1990 • 194 citations

Measurement of ligand-induced activation in single viable T cells using the lacZ reporter gene.

1991 • 191 citations

A functional role for nucleosomes in the repression of a yeast promoter.

1991 • 156 citations

Examination of the DNA-binding ability of estrogen receptor in whole cells: implications for hormone-independent transactivation and the actions of antiestrogens.

1992 • 125 citations

Threshold Phenomena and Long-Distance Activation of Transcription by RNA Polymerase II

1992 • 118 citations

Two Regions of the Mouse Mammary Tumor Virus Long Terminal Repeat Regulate the Activity of Its Promoter in Mammary Cell Lines

1991 • 88 citations

Glucocorticoids locally disrupt an array of positioned nucleosomes on the rat tyrosine aminotransferase promoter in hepatoma cells.

1990 • 74 citations

Binding of multiple factors to the MMTV promoter in crude and fractionated nuclear extracts

1988 • 68 citations

Mutations in the Hormone Regulatory Element of Mouse Mammary Tumor Virus Differentially Affect the Response to Progestins, Androgens, and Glucocorticoids

1989 • 57 citations

Apolipoprotein C-II mRNA levels in primate liver. Induction by estrogen in the human hepatocarcinoma cell line, HepG2.

1985 • 56 citations

The human estrogen receptor has transcriptional activator and repressor functions in the absence of ligand.

1990 • 55 citations

Retroviral mediated gene transfer into bone marrow progenitor cells: use of beta-galactosidase as a selectable marker

1990 • 27 citations

A novel fluorescence-based system for assaying and separating live cells according to VDJ recombinase activity.

1990 • 25 citations

Examination of the DNA-Binding Ability of Estrogen Receptor in Whole Cells: Implications for Hormone- Independent Transactivation and the Actions of Antiestrogens

1992 • 20 citations

A Novel Fluorescence-Based System for Assaying and Separating Live Cells according to VDJ Recombinase Activity

1990 • 10 citations

Induction of multiple replacement mutations by oligonucleotide-directed mutagenesis with extended mismatch primers

1987 • 5 citations