Cloning and expression of rat liver CTP: phosphocholine cytidylyltransferase: an amphipathic protein that controls phosphatidylcholine synthesis.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

A dot-immunobinding assay for monoclonal and other antibodies

1982 • 2,219 citations

All ras proteins are polyisoprenylated but only some are palmitoylated

1989 • 1,806 citations

Use of Helical Wheels to Represent the Structures of Proteins and to Identify Segments with Helical Potential

1967 • 1,178 citations

The helical hydrophobic moment: a measure of the amphiphilicity of a helix

1982 • 1,030 citations

Helix stabilization by Glu-...Lys+ salt bridges in short peptides of de novo design.

1987 • 930 citations

Internal amino acid sequence analysis of proteins separated by one- or two-dimensional gel electrophoresis after in situ protease digestion on nitrocellulose.

1987 • 819 citations

Substrate specificity of protein kinase C

1986 • 521 citations

Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence.

1989 • 439 citations

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation.

1985 • 386 citations

Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187.

1988 • 323 citations

Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl‐CoA carboxylase

1988 • 285 citations

Phosphorylation of RNA polymerase by the murine homologue of the cell-cycle control protein cdc2

1989 • 270 citations

Altered cytosol/membrane enzyme redistribution on interleukin-3 activation of protein kinase C

1985 • 255 citations

Signal for Attachment of a Phospholipid Membrane Anchor in Decay Accelerating Factor

1987 • 210 citations

PEPTIDES WITH AFFINITY FOR MEMBRANES

1987 • 179 citations

Talking point Amphitropic proteins: a new class of membrane proteins

1988 • 168 citations

Regulation of protein kinase C activity by lipids

1988 • 155 citations

The purification and characterization of CTP:phosphorylcholine cytidylyltransferase from rat liver.

1986 • 143 citations

An active twenty-amino-acid-residue peptide derived from the inhibitor protein of the cyclic AMP-dependent protein kinase

1985 • 119 citations

Translocation of CTP:phosphocholine cytidylyltransferase from cytosol to membranes in HeLa cells: stimulation by fatty acid, fatty alcohol, mono- and diacylglycerol

1987 • 119 citations

CTP:phosphorylcholine cytidylyltransferase in rat lung. The effect of free fatty acids on the translocation of activity between microsomes and cytosol.

1984 • 109 citations

Molecular cloning and characterization of the gene encoding cholinephosphate cytidylyltransferase in Saccharomyces cerevisiae

1987 • 101 citations

Chemical Cross-linking Reveals a Dimeric Structure for CTP: Phosphocholine Cytidylyltransferase

1989 • 82 citations

CTP: Phosphocholine Cytidylyltransferase Is a Substrate for cAMP-dependent Protein Kinase in Vitro

1989 • 78 citations

Regulation of phosphatidylcholine biosynthesis in Chinese hamster ovary cells by reversible membrane association of CTP: phosphocholine cytidylyltransferase.

1985 • 75 citations

CTP:phosphorylcholine cytidylyltransferase from rat liver. Isolation and characterization of the catalytic subunit.

1987 • 72 citations

Diacylglycerol-induced translocation of diacylglycerol kinase: use of affinity-purified enzyme in a reconstitution system.

1986 • 70 citations

Phosphorylation of CTP:phosphocholine cytidylyltransferase in vivo. Lack of effect of phorbol ester treatment in HeLa cells.

1990 • 68 citations

Amino acid sequence around the serine phosphorylated by casein kinase II in brain myosin heavy chain.

1990 • 61 citations

Characterization of cytosolic forms of CTP: choline-phosphate cytidylyltransferase in lung, isolated alveolar type II cells, A549 cell and Hep G2 cells

1989 • 58 citations

High-level expression of the Epstein-Barr virus EBNA1 protein in CV1 cells and human lymphoid cells using a SV40 late replacement vector

1986 • 53 citations

The stimulation and binding of CTP : Phosphorylcholine cytidylyltransferase by phosphatidylcholine-oleic acid vesicles

1985 • 52 citations

Binding of CTP:phosphocholine cytidylyltransferase to large unilamellar vesicles

1987 • 47 citations

Effect of phase transitions on the interaction of peptides and proteins with phospholipids

1984 • 27 citations

Characterization of the alpha-peptide released upon protease activation of pyruvate oxidase.

1985 • 24 citations

Identification of the high-affinity lipid binding site in Escherichia coli pyruvate oxidase

1986 • 17 citations