Genomic Analysis of the Thymine-DNA Glycosylase (TDG) Gene on 12q22-q24.1 in Human Pancreatic Ductal Adenocarcinoma

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

p53 Mutations in Human Cancers

1991 • 8,133 citations

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

1994 • 3,536 citations

Molecular cloning (2nd Ed)

1989 • 1,191 citations

Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

1995 • 824 citations

Tumor-suppressive pathways in pancreatic carcinoma.

1997 • 689 citations

Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas.

1997 • 632 citations

Establishment of a continuous tumor‐cell line (PANC‐1) from a human carcinoma of the exocrine pancreas

1975 • 478 citations

Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer.

1993 • 443 citations

Human pancreatic carcinoma (mia paca‐2) in continuous culture: Sensitivity to asparaginase

1977 • 364 citations

Allelotype of pancreatic adenocarcinoma using xenograft enrichment.

1995 • 308 citations

Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase

1996 • 255 citations

Characterization of a New Primary Human Pancreatic Tumor Line

1986 • 217 citations

A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase

1996 • 208 citations

Frequent gain of copy number on the long arm of chromosome 20 in human pancreatic adenocarcinoma

1997 • 125 citations

Importance of E-selectin (ELAM-1) and sialyl lewisa in the adhesion of pancreatic carcinoma cells to acttvated endothelium

1993 • 117 citations

Infrequent Genetic Alterations of the PTEN/MMAC1 Gene in Japanese Patients with Primary Cancers of the Breast, Lung, Pancreas, Kidney, and Ovary

1997 • 107 citations

Genomic analysis of DUSP6, a dual specificity MAP kinase phosphatase, in pancreatic cancer

1998 • 77 citations

Detailed deletion mapping on chromosome arm 12q in human pancreatic adenocarcinoma: Identification of a 1-cM region of common allelic loss

1996 • 74 citations

Localization and polymorphism of a chromosome 12-specific α satellite DNA sequence

1990 • 73 citations

Phenotypes correlating to metastatic properties of pancreas adenocarcinoma in vivo: The importance of surface sialyl Lewisa antigen

1996 • 69 citations

Identification of two common regions of allelic loss in chromosome arm 12q in human pancreatic cancer.

1998 • 63 citations

Clonal allele loss in gastrointestinal cancers

1989 • 55 citations

Establishment of six human pancreatic cancer cell lines and their sensitivities to anti-tumor drugs.

1986 • 47 citations

Physical Mapping of a Commonly Deleted Region, the Site of a Candidate Tumor Suppressor Gene, at 12q22 in Human Male Germ Cell Tumors

1996 • 40 citations

Human thymine-DNA glycosylase maps at chromosome 12q22-q24.1: a region of high loss of heterozygosity in gastric cancer.

1997 • 39 citations

Identification of a 790-kilobase region of common allelic loss in chromosome 10q25-q26 in human endometrial cancer.

1997 • 31 citations

A new human pancreatic carcinoma cell line developed for adoptive immunotherapy studies with lymphokine-activated killer cells in nude mice

1988 • 30 citations

Autonomous production of granulocyte-colony stimulating factor in tumour xenografts associated with leukocytosis

1993 • 24 citations

Chromosomal Localizations and Molecular Analysis ofTDGGene-Related Sequences

1997 • 14 citations

Stability of ras oncogene mutation in the human tumor xenografts through serial passages.

1994 • 8 citations

Frameshift mutation at codon 642 of thehMLH1 gene in human endometrial cancer

1996 • 2 citations