An improved flow cytometric assay for the determination of cytotoxic T lymphocyte activity

A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1995 • 5,208 citations

Immunobiology: the immune system in health and disease

1995 • 3,893 citations

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

1995 • 2,877 citations

Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs.

1968 • 1,363 citations

Cell-Mediated Cytotoxicity, Allograft Rejection, and Tumor Immunity

1974 • 1,161 citations

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity.

1993 • 801 citations

Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids

1985 • 580 citations

Lymphocyte-mediated cytotoxicity: Two pathways and multiple effector molecules

1994 • 414 citations

Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generatedin vitro from CD34+ hematopoietic progenitor cells

2000 • 337 citations

CARE-LASS (calcein-release-assay), an improved fluorescence-based test system to measure cytotoxic T lymphocyte activity

1994 • 267 citations

Annexin V used for measuring apoptosis in the early events of cellular cytotoxicity

1999 • 240 citations

Cytolytic and cytostatic activity on tumor cells of circulating human monocytes

1979 • 177 citations

Characterization of the cytolytic reaction mechanism of the human natural killer (NK) lymphocyte: resolution into binding, programming, and killer cell-independent steps.

1982 • 177 citations

Direct evidence to support the immunosurveillance concept in a human regressive melanoma.

1994 • 171 citations

A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis

2001 • 166 citations

Cell-mediated cytotoxicity

1989 • 165 citations

Generation and purification of CD8+ melan-A-specific cytotoxic T lymphocytes for adoptive transfer in tumor immunotherapy.

2000 • 85 citations

Lactate dehydrogenase-release assay: A reliable, nonradioactive technique for analysis of cytotoxic lymphocyte-mediated lytic activity against blasts from acute myelocytic leukemia

1995 • 84 citations

A novel non-radioactive cellular cytotoxicity test based on the differential assessment of living and killed target and effector cells

1995 • 72 citations

A versatile flow cytometry-based assay for the determination of short- and long-term natural killer cell activity

1995 • 66 citations

Analyzing cytotoxic T lymphocyte activity: a simple and reliable flow cytometry-based assay

1997 • 60 citations

Rapid turnover of the recirculating lymphocyte pool in vivo

1995 • 55 citations

Enhancement of Antibody Dependent Cellular Cytotoxicity (ADCC) by Combination of Cytokines

1999 • 36 citations

A new flow cytometric method for quantitative assessment of lymphocyte mitogenic potentials.

1995 • 35 citations

An improved assay for antibody dependent cellular cytotoxicity based on time resolved fluorometry

1995 • 29 citations

Multiple epitope recognition: An approach to improved radioimmunodetection of tumor‐associated antigens

1987 • 25 citations

Transformed and Nontransformed Human T Lymphocytes Migrate to Skin in a Chimeric Human Skin/SCID Mouse Model.

1997 • 16 citations

Cytotoxic T lymphocyte control during ectromelia (mousepox) virus infection: interaction between MHC-restricted cells analyzed by non-radioactive fluorometry.

1996 • 10 citations