IL‐6 Is the Principal Factor Produced by Synovia of Patients with Rheumatoid Arthritis That Induces B‐Lymphocytes to Secrete Immunoglobulins

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones

1986 • 1,521 citations

A plaque assay for all cells secreting Ig of a given type or class

1976 • 1,034 citations

Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes.

1986 • 777 citations

Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells.

1986 • 632 citations

Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA.

1988 • 510 citations

Corticotropin-Releasing Activity of Monokines

1985 • 500 citations

Human Lymphocytes Making Rheumatoid Factor and Antibody to ssDNA Belong to Leu-1⁺B-Cell Subset

1987 • 490 citations

Rheumatoid Factor Secretion from Human Leu-1 ⁺ B Cells

1987 • 442 citations

Interleukin 6 is involved in interleukin 1‐induced activities

1988 • 422 citations

In vitro synthesis of immunoglobulin by rheumatoid synovial membrane

1968 • 324 citations

Transforming growth factor-beta 1 modulates the expression of class II histocompatibility antigens on human cells.

1988 • 298 citations

Regulation of interleukin-6 expression in cultured human blood monocytes and monocyte-derived macrophages

1988 • 234 citations

A rheumatoid arthritis b cell subset expresses a phenotype similar to that in chronic lymphocytic leukemia

1985 • 228 citations

Human β ₂ Interferon and B-Cell Differentiation Factor BSF-2 Are Identical

1987 • 204 citations

Immunohistologic characterization of synovial membrane lymphocytes in rheumatoid arthritis

1984 • 179 citations

The acute phase response of the liver in inflammation.

1990 • 171 citations

Monoclonal antibodies to human recombinant interleukin 1 (IL 1)beta: quantitation of IL 1 beta and inhibition of biological activity.

1987 • 115 citations

Interleukin 1: a regulatory role in glucocorticoid-regulated hepatic metabolism.

1986 • 95 citations

In vivo synthesis of IgG by rheumatoid synovium.

1970 • 95 citations

IgG and IgM rheumatoid factor synthesis in rheumatoid synovial membrane cell cultures

1985 • 85 citations

Effect of B cell differentiation factor (BCDF) on biosynthesis and secretion of immunoglobulin molecules in human B cell lines.

1985 • 75 citations

B Cell Differentiation Factor in Synovial Fluid of Patients with Rheumatoid Arthritis

1984 • 59 citations

Regulation of human B cell activation by prostaglandin E2. Suppression of the generation of immunoglobulin-secreting cells.

1985 • 54 citations

A new interleukin with pleiotropic activities

1988 • 29 citations

A Comparison Between Clinical and Laboratory Tests in Rheumatoid Arthritis

1983 • 18 citations

Distribution of activated B lymphocytes in the circulation and synovial fluid in rheumatoid arthritis

1984 • 16 citations

Recombinant human interleukin‐1 inhibits the induction by dexamethasone of alkaline phosphatase activity in murine capillary endothelial cells

1987 • 14 citations

Immunopathogenetic mechanisms of arthritis and modes of action of antirheumatic therapies

1988 • 10 citations

Pro-Inflammatory and Catabolic Effects of Interleukin-1 and their Antagonism by Glucocorticoids

1988 • 6 citations

On the Development of Teeth in the Lamprey

1883 • 3 citations