Antidepressant and other centrally acting drugs regulate glucocorticoid receptor messenger RNA levels in rat brain

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Psychopharmacology: The third generation of progress

1988 • 3,403 citations

Extension of Multiple Range Tests to Group Means with Unequal Numbers of Replications

1956 • 3,120 citations

Distribution of serotonin-immunoreactivity in the central nervous system of the rat—Cell bodies and terminals

1981 • 2,392 citations

Organization of Ovine Corticotropin-Releasing Factor Immunoreactive Cells and Fibers in the Rat Brain: An Immunohistochemical Study

1983 • 1,954 citations

Sex Differences and the Epidemiology of Depression

1977 • 1,847 citations

Responses to Corticotropin-Releasing Hormone in the Hypercortisolism of Depression and Cushing's Disease

1986 • 773 citations

Disrupted 24-hour Patterns of Cortisol Secretion in Psychotic Depression

1973 • 761 citations

Effect of antidepressant drugs on the depletion of intraneuronal brain 5-hydroxytryptamine stores caused by 4-methyl-α-ethyl-meta-tyramine

1969 • 645 citations

Neuroendocrine Regulation in Depression

1976 • 623 citations

Organization of ascending serotonin systems in the adult rat brain. A radioautographic study after intraventricular administration of [3h]5-hydroxytryptamine

1981 • 527 citations

SEX DIFFERENCES IN ADRENAL CORTICAL SECRETION IN THE RAT¹

1961 • 522 citations

Mapping of Glucocorticoid Receptor Immunoreactive Neurons in the Rat Tel- and Diencephalon Using a Monoclonal Antibody against Rat Liver Glucocorticoid Receptor*

1985 • 512 citations

Lithium in psychiatric therapy and prophylaxis

1968 • 496 citations

Psychiatric implications of basic and clinical studies with corticotropin-releasing factor

1984 • 486 citations

Lithium inhibits adrenergic and cholinergic increases in GTP binding in rat cortex

1988 • 474 citations

Sex Differences and Psychiatric Disorders

1976 • 429 citations

Effects of some antidepressant drugs on the depletion of intraneuronal brain catecholamine stores caused by 4,α-dimethyl-meta-tyramine

1969 • 417 citations

The 24-Hour Profile of Adrenocorticotropin and Cortisol in Major Depressive Illness*

1985 • 401 citations

Zur Serotonin-Hypothese der Depression*

1990 • 397 citations

Cortisol Production in Depressive Illness

1970 • 371 citations

Dexamethasone Suppression Tests in Antidepressant Treatment of Melancholia

1983 • 360 citations

Female rats are more vulnerable than males in an animal model of depression: the possible role of serotonin

1986 • 298 citations

Lithium Carbonate Addition in Tricyclic Antidepressant—Resistant Unipolar Depression

1983 • 297 citations

Lithium Carbonate Augmentation of Antidepressant Treatment

1983 • 285 citations

Resistance to Suppression by Dexamethasone of Plasma 11-O.H.C.S. Levels in Severe Depressive Illness

1968 • 278 citations

Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells

1984 • 278 citations

Down-regulation of glucocorticoid receptor mRNA by glucocorticoid hormones and recognition by the receptor of a specific binding sequence within a receptor cDNA clone.

1986 • 260 citations

Modulation by estradiol of serotonin receptors in brain

1982 • 237 citations

Tissue-specific regulation of glucocorticoid receptor mRNA by dexamethasone.

1987 • 229 citations

Comparison of stress response in male and female rats: Pituitary cyclic AMP and plasma prolactin, growth hormone and corticosterone

1983 • 208 citations

Effect of 5-Hydroxytryptophan on Serum Cortisol Levels in Major Affective Disorders

1984 • 197 citations

Regulation of Glucocorticoid Receptors in Brain by Corticosterone Treatment of Adrenalectomized Rats

1982 • 159 citations

Control of ACTH Secretion by the Central Nucleus of the Amygdala: Implication of the Serotoninergic System and Its Relevance to the Glucocorticoid Delayed Negative Feedback Mechanism

1986 • 153 citations

Regulation of actin mRNA levels and translation responds to changes in cell configuration.

1983 • 148 citations

Participation of the Central Amygdaloid Nucleus in the Response of Adrenocorticotropin Secretion to Immobilization Stress: Opposing Roles of the Noradrenergic and Dopaminergic Systems

1987 • 141 citations

Antidepressants regulate glucocorticoid receptor messenger RNA concentrations in primary neuronal cultures

1989 • 134 citations

Sexual dimorphism of glucocorticoid binding in rat brain

1985 • 129 citations

ACTH and multisteroid responses to corticotropin-releasing factor in depressive illness: Relationship to multisteroid responses after ACTH stimulation and dexamethasone suppression☆

1984 • 119 citations

Cortisol in the CSF of Depressed and Suicidal Patients

1980 • 118 citations

ACTH, cortisol, and corticosterone output after ovine corticotropin-releasing factor challenge during depression and after recovery

1985 • 99 citations

Imipramine: Effect of Ovarian Steroids on Modifications in Serotonin Receptor Binding

1981 • 99 citations

Lithium carbonate addition in tricyclic antidepressant-resistant unipolar depression

1984 • 97 citations

Hormonal Regulation of Type II Glucocorticoid Receptor Messenger Ribonucleic Acid in Rat Brain*

1991 • 97 citations

Pituitary and Adrenocortical Responses to the Ovine Corticotropin Releasing Hormone in Depressed Patients and Healthy Volunteers

1987 • 97 citations

Lithium carbonate augmentation of antidepressant treatment

1984 • 96 citations

Effect of 5-Hydroxytryptophan on Serum Cortisol Levels in Major Affective Disorders

1984 • 90 citations

Ultrastructural localization of glucocorticoid receptor (GR) in hypothalamic paraventricular neurons synthesizing corticotropin releasing factor (CRF)

1987 • 88 citations

The corticotropin releasing factor (CRF) neurosecretory system in intact, adrenalectomized, and adrenalectomized-dexamethasone treated rats

1983 • 88 citations

Effect of treatment of rats with antidepressants on melatonin concentrations in the pineal gland and serum.

1982 • 83 citations

Lithium Blocks a Phosphoinositide-Mediated Cholinergic Response in Hippocampal Slices

1988 • 81 citations

Radioautographic study of the rat brain and pituitary after injection of 3H dexamethasone

1975 • 80 citations

The pharmacokinetic profile of lithium in rat and mouse; An important factor in psychopharmacological investigation of the drug

1986 • 68 citations

Influence of the Central Nucleus of the Amygdala on the Content of Corticotropin-Releasing Factor in the Median Eminence

1989 • 68 citations

Estrogen-Induced Decrease of Glucocorticoid Receptor Messenger Ribonucleic Acid Concentration in Rat Anterior Pituitary Gland

1987 • 63 citations

The effects of antidepressant treatments and lithium upon 5-HT1A receptor function

1989 • 57 citations

Adrenocortical responsiveness to the ACTH stimulation test in depressed patients and healthy volunteers

1986 • 41 citations

Antihypertensive properties of ketanserin (R 41 468).

1983 • 36 citations

Recurrent Premenstrual Decline in Serum Lithium Concentration: Clinical Correlates and Treatment Implications

1986 • 31 citations

Distribution of corticotropin-releasing factor in ovine brain determined by radioimmunoassay

1983 • 29 citations

Glucocorticoid receptor gene expression in rat pituitary gland intermediate lobe following ovariectomy

1988 • 29 citations

Proceedings: Variations in the concentrations of monamines and their metabolites in eight regions of rat brain during the oestrous cycle: a basis for interactions between hormones and psychotropic drugs.

1975 • 28 citations

Decreased Glucocorticoid Receptor Activity Following Glucocorticoid Receptor Antisense RNA Gene Fragment Transfection

1991 • 26 citations

Lithium: Short-term and chronic effects on plasma testosterone and luteinizing hormone concentrations in mice

1982 • 21 citations

Acute lithium treatment suppresses the proestrous LH surge in mice: chronic lithium leads to constant diestrus

1986 • 15 citations

Action of chronically administered antidepressants on the serotonergic postsynapse in a model of depression

1986 • 14 citations

Effects of lithium on the pituitary-gonadal axis in the rat: Evidence for dose-dependent changes in plasma gonadotropin and testosterone levels

1987 • 13 citations

Serotoninergic innervation and glucocorticoid binding in the hippocampus: relevance to depression.

1982 • 12 citations

Effects of short-term lithium administration on tryptophan levels and 5-hydroxytryptamine synthesis in whole brain and brain regions in rats

1987 • 11 citations

Immunocytochemical Analysis

2003 • 8 citations

Lithium suppresses ovariectomy-induced surges in plasma gonadotropins in rats

1989 • 8 citations