Involvement of Ral GTPase in v-Src-induced phospholipase D activation

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Mammalian Ras interacts directly with the serine/threonine kinase raf

1993 • 1,983 citations

Phosphatidylinositol-3-OH kinase direct target of Ras

1994 • 1,923 citations

Complexes of Ras⋅GTP with Raf-1 and Mitogen-Activated Protein Kinase Kinase

1993 • 987 citations

ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity

1993 • 900 citations

Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family

1982 • 836 citations

Inhibition of NIH 3T3 Cell Proliferation by a Mutant ras Protein with Preferential Affinity for GDP

1988 • 757 citations

Phospholipase D: a Downstream Effector of ARF in Granulocytes

1994 • 636 citations

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

1988 • 470 citations

Identification and Characterization of Ral-Binding Protein 1, a Potential Downstream Target of Ral GTPases

1995 • 304 citations

Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator.

1994 • 281 citations

Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap.

1994 • 270 citations

Activation of rat liver phospholipase D by the small GTP-binding protein RhoA

1994 • 265 citations

ralGDS family members interact with the effector loop of ras p21.

1994 • 260 citations

Neutrophil phospholipase D is activated by a membrane-associated Rho family small molecular weight GTP-binding protein.

1993 • 229 citations

Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP.

1991 • 211 citations

Regulation of Phospholipase D in HL60 Cells

1995 • 145 citations

v-Src increases diacylglycerol levels via a type D phospholipase-mediated hydrolysis of phosphatidylcholine.

1991 • 111 citations

ADP-ribosylation Factor Functions Synergistically with a 50-kDa Cytosolic Factor in Cell-free Activation of Human Neutrophil Phospholipase D

1995 • 101 citations

Ras Mediates the Activation of Phospholipase D by v-Src

1995 • 87 citations

Activation of type D phospholipase by serum stimulation and ras-induced transformation in NIH3T3 cells.

1994 • 83 citations

Characterization of a GTPase-activating protein for the Ras-related Ral protein

1991 • 63 citations

v-Src activates a unique phospholipase D activity that can be distinguished from the phospholipase D activity activated by phorbol esters

1993 • 60 citations

Intracellular signalling mediated by protein-tyrosine kinases: Networking through phospholipid metabolism

1993 • 49 citations

Evidence that Ha-Ras mediates two distinguishable intracellular signals activated by v-Src.

1992 • 42 citations