Interleukin-4 modulates the proliferation and differentiation of glial cells

Molecular profile of reactive astrocytes—Implications for their role in neurologic disease

1993 • 1,436 citations

Interleukin-4: a prototypic immunoregulatory lymphokine

1991 • 878 citations

Interleukin-1 Stimulation of Astroglial Proliferation After Brain Injury

1985 • 855 citations

Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells.

1982 • 754 citations

Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation.

1983 • 564 citations

Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: Lesion effects in the rat brain and levels in Alzheimer's disease

1986 • 335 citations

Synthesis and secretion of nerve growth factor by mouse astroglial cells in culture

1986 • 278 citations

Expression of high affinity receptors for murine interleukin 4 (BSF-1) on hemopoietic and nonhemopoietic cells.

1988 • 244 citations

Trophic effects of interleukin-4, -7 and -8 on hippocampal neuronal cultures: potential involvement of glial-derived factors

1993 • 244 citations

Neuroprotective role of IL-4 against activated microglia.

1993 • 214 citations

Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines

1992 • 207 citations

B-cell stimulatory factor 1 activates resting B cells.

1985 • 201 citations

Astrocytes of the brain synthesize interleukin 3-like factors.

1985 • 177 citations

"Transdifferentiation" of C6 Glial Cells in Culture

1980 • 175 citations

Biochemical and Ultrastructural Studies of Cultured Rat Astroglial Cells

1980 • 166 citations

Cytokines: Influence on Glial Cell Gene Expression and Function

1997 • 145 citations

Neuromodulative actions of cytokines.

1990 • 116 citations

Interleukin 4 activates human B lymphocytes via transient inositol lipid hydrolysis and delayed cyclic adenosine monophosphate generation

1990 • 113 citations

Early and late passage C-6 glial cell growth: Similarities with primary glial cells in culture

1989 • 96 citations

Differential proliferative response of human and mouse astrocytes to gamma‐interferon

1992 • 84 citations

Interleukin‐4 and ‐5 as modulators of nerve growth factor synthesis/secretion in astrocytes

1993 • 77 citations

Interleukin-1β induction of tumor necrosis factor-alpha gene expression in human astroglioma cells

1992 • 77 citations

Identification of interleukin 4 receptor‐associated proteins and expression of both high‐ and low‐affinity binding on human lymphoid cells

1989 • 75 citations

B cell stimulatory factor 1 (IL-4) enhances the development of cytotoxic T cells from Lyt-2+ resting murine T lymphocytes.

1988 • 71 citations

Biochemical and physicochemical characterization of mouse B cell growth factor: a lymphokine distinct from interleukin 2.

1983 • 68 citations

Augmentation of major histocompatibility complex class I and ICAM‐1 expression on glial cells following measles virus infection: Evidence for the role of type‐1 interferon

1992 • 53 citations

Independent regulation of interleukin 4 (IL-4)-induced expression of human B cell surface CD23 and IgM: functional evidence for two IL-4 receptors

1991 • 46 citations

Synthesis of Glial Fibrillary Acidic Protein in Rat C₆ Glioma in Chemically Defined Medium: Cyclic AMP‐Dependent Transcriptional and Translational Regulation

1992 • 40 citations

Involvement of Nitric Oxide on the Cytokine-Induced Growth of Glial Cell

1993 • 38 citations

Glutamine Synthetase: A Marker of an Astroglial Subpopulation in Primary Cultures of Defined Brain Areas

1988 • 32 citations

Interleukin-4 down-regulates adult human astrocyte DNA synthesis and proliferation.

1993 • 30 citations

C-6 Glioma Cells of Early Passage Have Progenitor Properties in Culture

1991 • 24 citations

Modulation of Proliferation and Antigen Expression of a Cloned Human Glioblastoma by Interleukin-4 Alone and in Combination with Tumor Necrosis Factor-α and/or Interferon-γ

1993 • 21 citations