THE EFFECT OF COMPLEMENT DEPLETION ON EXPERIMENTAL TISSUE INJURY*

The immunologic release of constituents from neutrophil leukocytes. I. The role of antibody and complement on nonphagocytosable surfaces or phagocytosable particles.

1971 • 513 citations

Depletion of plasma complement in vivo by a protein of cobra venom: its effect on various immunologic reactions

1971 • 465 citations

ISOLATION OF A FRAGMENT (C3a) OF THE THIRD COMPONENT OF HUMAN COMPLEMENT CONTAINING ANAPHYLATOXIN AND CHEMOTACTIC ACTIVITY AND DESCRIPTION OF AN ANAPHYLATOXIN INACTIVATOR OF HUMAN SERUM

1969 • 430 citations

A ROLE OF POLYMORPHONUCLEAR LEUKOCYTES AND COMPLEMENT IN NEPHROTOXIC NEPHRITIS

1965 • 421 citations

The Immunologic Release of Constituents from Neutrophil Leukocytes

1971 • 319 citations

Two Anticomplementary Factors in Cobra Venom: Hemolysis of Guinea Pig Erythrocytes by One of Them

1969 • 301 citations

Depletion of Plasma Complement in Vivo by a Protein of Cobra Venom: Its Effect on Various Immunologic Reactions

1970 • 294 citations

POLYMORPHONUCLEAR LEUKOCYTES IN IMMUNOLOGIC REACTIONS

1966 • 266 citations

BOUND COMPLEMENT AND IMMUNOLOGIC INJURY OF BLOOD VESSELS

1965 • 238 citations

The ability of chemotactic factors to induce lysosomal enzyme release. I. The characteristics of the release, the importance of surfaces and the relation of enzyme release to chemotactic responsiveness.

1974 • 212 citations

REACTIVE LYSIS: THE COMPLEMENT-MEDIATED LYSIS OF UNSENSITIZED CELLS

1970 • 198 citations

ACUTE IMMUNE COMPLEX DISEASE IN RABBITS

1971 • 188 citations

The adherence of leucocytes and platelets induced by fixed IgG antibody or complement.

1969 • 186 citations

Pathologic mechanisms in neutrophil-mediated injury.

1972 • 180 citations

Isolation of the Anticomplementary Protein from Cobra Venom and its Mode of Action on C3

1971 • 173 citations

RELEASE OF VASOACTIVE AMINES FROM RABBIT PLATELETS INDUCED BY SENSITIZED MONONUCLEAR LEUKOCYTES AND ANTIGEN

1970 • 170 citations

PATHOGENESIS OF CHRONIC DISEASE ASSOCIATED WITH PERSISTENT LYMPHOCYTIC CHORIOMENINGITIS VIRAL INFECTION

1970 • 163 citations

EXPERIMENTAL GLOMERULONEPHRITIS

1964 • 162 citations

Release of Serotonin from Human Platelets Induced by Aggregated Immunoglobulins of Different Classes and Subclasses

1973 • 160 citations

Glomerular basement membrane damage in immunological glomerulonephritis.

1968 • 145 citations

A new concept of immunosuppression in hypersensitivity reactions and in transplantation immunity.

1966 • 135 citations

The Ability of Chemotactic Factors to Induce Lysosomal Enzyme Release

1974 • 128 citations

Biological activities of complement

1973 • 126 citations

Leucocyte mobilizing factor: A new biological activity derived from the third component of complement

1972 • 82 citations

The in vivo behaviour of complement-coated red cells: studies in C6-deficient, C3-depleted and normal rabbits.

1970 • 80 citations

FORMATION AND FUNCTION OF A COMPLEX OF THE C3 PROACTIVATOR WITH A PROTEIN FROM COBRA VENOM

1973 • 74 citations

AN ULTRASTRUCTURAL STUDY OF THE MECHANISMS OF PLATELET-ENDOTOXIN INTERACTION

1967 • 71 citations

The Behaviour of Complement and Platelets in Lethal Endotoxin Shock in Rabbits

1973 • 68 citations

The role of PMN-leucocyte lysosomes in tissue injury, inflammation and hypersensitivity. VI. The participation of the PMN-leucocyte and the blood platelet in systemic aggregate anaphylaxis.

1968 • 58 citations

Acute Immunologic Arthritis in Rabbits

1972 • 58 citations

IMMUNOLOGICAL INDUCTION OF INCREASED VASCULAR PERMEABILITY

1969 • 54 citations

The Effect of Complement Depletion on Neutrophil Migration in Acute Immunologic Arthritis

1972 • 36 citations

Nonimmune chemotaxis in vivo: inhibition by complement depletion with cobra factor.

1973 • 35 citations

Guinea-pig nephrotoxic nephritis. I. The role of complement and polymorphonuclear leucocytes and the effect of antibody subclass and fragments in the heterologous phase.

1975 • 33 citations

Release of Biologically Active Constituents from Blood Cells and its Role in Antibody-Mediated Tissue Injury**Publication No. 496 from the Department of Experimental Pathology, Scripps Clinic and Research Foundation, La Jolla, California. This work was supported by the U. S. Public Health Service Grant AI-07007 and a grant from the Council for Tobacco Research, U.S.A.

1971 • 28 citations

The Effect of Cobra Venom Factor on Hemostasis in Guinea Pigs

1972 • 24 citations

THE RELATIONSHIPS BETWEEN SERUM COMPLEMENT ACTIVITY AND THE DEVELOPMENT OF ALLERGIC LESIONS IN RABBITS

1961 • 23 citations

Factor D in the alternative pathway of complement activation: Purification, physicochemical characterization and functional role

1974 • 17 citations

Metabolism of radio-labelled C3: effects of in vivo activation in rabbits.

1974 • 16 citations

Complement-dependent platelet and polymorphonuclear leukocyte reactions.

1974 • 15 citations

Acute Complement‐mediated Haemolysis in the Rabbit: Relationship between the Thrombocytopenia and Neutropenia and Complement Consumption

1970 • 11 citations

Effect of cobra venom factor on the local GVH reaction. I. Partial characterization of a cytotoxic factor from cobra venom for rat lymphocytes.

1973 • 10 citations

Studies on the nephrotoxic activity of guinea-pig gamma-1 and gamma-2 antibodies.

1974 • 6 citations

Effect of Cobra Venom Factor on the Local GVH Reaction

1973 • 5 citations

The participation of complement in renal disease and allograft rejection as assessed by model animal systems.

1974 • 4 citations

The Platelet in C-Blood Coagulation Interaction

1973 • 3 citations

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