Diminished Response of Werner's Syndrome Fibroblasts to Growth Factors PDGF and FGF

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1983 • 1,550 citations

Hybridization of nucleic acids immobilized on solid supports

1984 • 1,357 citations

Cytoplasmic dot hybridization. Simple analysis of relative mRNA levels in multiple small cell or tissue samples.

1982 • 1,333 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

A Review of its Symptomatology, Natural History, Pathologic Features, Genetics And Relationship to the Natural Aging Process

1966 • 831 citations

Platelet-derived growth factor in chemotactic for fibroblasts.

1982 • 744 citations

The platelet-derived growth factor

1978 • 649 citations

Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein.

1986 • 645 citations

Functional role for c-myc in mitogenic response to platelet-derived growth factor

1984 • 578 citations

Chemotaxis of monocytes and neutrophils to platelet-derived growth factor.

1982 • 553 citations

Attachment of smooth muscle cells to collagen and their migration toward platelet-derived growth factor.

1981 • 506 citations

Expression of the c- fos Gene and of an fos -Related Gene Is Stimulated by Platelet-Derived Growth Factor

1984 • 445 citations

The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor.

1984 • 376 citations

Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor

1983 • 352 citations

c-myc gene expression is stimulated by agents that activate protein kinase C and does not account for the mitogenic effect of PDGF

1985 • 331 citations

Platelet-derived growth factor stimulates tyrosine-specific protein kinase activity in Swiss mouse 3T3 cell membranes.

1982 • 293 citations

Stimulation of granulation tissue formation by platelet-derived growth factor in normal and diabetic rats.

1985 • 277 citations

Chemotactic activity of platelet alpha granule proteins for fibroblasts.

1983 • 275 citations

Werner's syndrome: A review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations

1982 • 254 citations

Expression of a Platelet-Derived Growth Factor-Like Protein in Simian Sarcoma Virus Transformed Cells

1983 • 246 citations

Stimulation of in vitro human skin collagenase expression by platelet-derived growth factor.

1985 • 236 citations

Platelet-derived growth factor. Structure, function, and roles in normal and transformed cells.

1984 • 178 citations

Platelet-derived growth factor. Specific binding to target cells.

1982 • 163 citations

Production of phosphoinositide-derived messengers

1984 • 163 citations

Werner’s Syndrome (Progeria of the Adult) and Rothmund’s Syndrome: Two Types of Closely Related Heredofamilial Atrophic Dermatoses with Juvenile Cataracts and Endocrine Features; A Critical Study with Five New Cases

1985 • 158 citations

Werner's syndrome

1973 • 154 citations

WERNER'S SYNDROME (PROGERIA OF THE ADULT) AND ROTHMUND'S SYNDROME: TWO TYPES OF CLOSELY RELATED HEREDOFAMILIAL ATROPHIC DERMATOSES WITH JUVENILE CATARACTS AND ENDOCRINE FEATURES; A CRITICAL STUDY WITH FIVE NEW CASES

1945 • 134 citations

Systematic growth studies, cocultivation, and cell hybridization studies of Werner syndrome cultured skin fibroblasts

1981 • 109 citations

Biosynthesis of collagenase by human skin fibroblasts in monolayer culture.

1979 • 87 citations

Urinary excretion of macromolecular acidic glycosaminoglycans in Werner's syndrome

1978 • 60 citations

Urinary acidic glycosaminoglycans in Werner's syndrome

1982 • 28 citations

Werner's Syndrome

1985 • 24 citations

Collagen synthesis of cultured fibroblast from Werner's syndromes of premature aging

1978 • 20 citations