Folding pattern of the α-crystallin domain in αA-crystallin determined by site-directed spin labeling

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

Comparative Protein Modelling by Satisfaction of Spatial Restraints

1993 • 12,640 citations

The Structure of the Potassium Channel: Molecular Basis of K ⁺ Conduction and Selectivity

1998 • 6,595 citations

The Hsp70 and Hsp60 Chaperone Machines

1998 • 2,793 citations

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution

1998 • 2,377 citations

THE FUNCTION OF HEAT-SHOCK PROTEINS IN STRESS TOLERANCE: DEGRADATION AND REACTIVATION OF DAMAGED PROTEINS

1993 • 2,177 citations

Alpha-crystallin can function as a molecular chaperone.

1992 • 1,822 citations

A missense mutation in the αB-crystallin chaperone gene causes a desmin-related myopathy

1998 • 1,061 citations

Biological Magnetic Resonance

1982 • 941 citations

Crystal structure of a small heat-shock protein

1998 • 876 citations

Protein disaggregation mediated by heat-shock protein Hspl04

1994 • 861 citations

Comparative protein modeling by satisfaction of spatial restraints

1995 • 785 citations

A small heat shock protein stably binds heat-denatured model substrates and can maintain a substrate in a folding-competent state

1997 • 772 citations

Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation

1997 • 750 citations

The Immunoglobulin Fold

1994 • 679 citations

PRINCIPLES THAT DETERMINE THE STRUCTURE OF PROTEINS

1984 • 645 citations

Motion of Spin-Labeled Side Chains in T4 Lysozyme. Correlation with Protein Structure and Dynamics

1996 • 551 citations

Recent advances in site-directed spin labeling of proteins

1998 • 543 citations

The synaptic SNARE complex is a parallel four-stranded helical bundle

1998 • 497 citations

Genealogy of the α-crystallin—small heat-shock protein superfamily

1998 • 480 citations

Evolution of the alpha-crystallin/small heat-shock protein family.

1993 • 464 citations

Determination of the distance between two spin labels attached to a macromolecule.

1995 • 399 citations

Principles of protein folding in the cellular environment

1999 • 349 citations

The expanding small heat-shock protein family, and structure predictions of the conserved “α-crystallin domain”

1995 • 348 citations

Structure and in Vitro Molecular Chaperone Activity of Cytosolic Small Heat Shock Proteins from Pea

1995 • 322 citations

THE CLASSIFICATION AND ORIGINS OF PROTEIN FOLDING PATTERNS

1990 • 308 citations

A novel reversible thiol-specific spin label: Papain active site labeling and inhibition

1982 • 303 citations

Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy

1998 • 297 citations

Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

1998 • 297 citations

Studies on Protein Stability With T4 Lysozyme

1995 • 291 citations

Subunit Exchange of αA-Crystallin

1997 • 286 citations

The small heat-shock protein, αb-crystallin, has a variable quaternary structure

1998 • 286 citations

Temperature‐induced exposure of hydrophobic surfaces and its effect on the chaperone activity of α‐crystallin

1995 • 278 citations

A dysfunctional desmin mutation in a patient with severe generalized myopathy

1998 • 255 citations

Mycobacterium tuberculosis 16-kDa Antigen (Hsp16.3) Functions as an Oligomeric Structure in Vitro to Suppress Thermal Aggregation

1996 • 230 citations

Incorporation of glutamine repeats makes protein oligomerize: implications for neurodegenerative diseases.

1995 • 223 citations

Short alanine-based peptides may form 310-helices and not α-helices in aqueous solution

1992 • 205 citations

Conformation of T4 Lysozyme in Solution. Hinge-Bending Motion and the Substrate-Induced Conformational Transition Studied by Site-Directed Spin Labeling

1997 • 202 citations

Interaction of .alpha.-crystallin with Spin-Labeled Peptides

1995 • 185 citations

Continuous and stopped flow EPR spectrometer based on a loop gap resonator

1987 • 145 citations

Molecular distances from dipolar coupled spin-labels: the global analysis of multifrequency continuous wave electron paramagnetic resonance data

1997 • 140 citations

Proctor Lecture. The function of alpha-crystallin.

1993 • 139 citations

Immobilization of the C-terminal Extension of Bovine αA-Crystallin Reduces Chaperone-like Activity

1996 • 126 citations

SPIN LABELED CYSTEINES AS SENSORS FOR PROTEIN‐LIPID INTERACTION AND CONFORMATION IN RHODOPSIN

1992 • 115 citations

Functional Elements in Molecular Chaperone α-Crystallin: Identification of Binding Sites in αB-Crystallin

1997 • 114 citations

ESR Characterization of Hexameric, Helical Peptides Using Double TOAC Spin Labeling

1996 • 109 citations

Intermolecular Exchange and Stabilization of Recombinant Human αA- and αB-Crystallin

1998 • 103 citations

Relative orientation of close-packed β-pleated sheets in proteins

1981 • 99 citations

Structure and Function of the Conserved Domain in αA-Crystallin. Site-Directed Spin Labeling Identifies a β-Strand Located near a Subunit Interface

1997 • 92 citations

Site-directed Spin Labeling Study of Subunit Interactions in the α-Crystallin Domain of Small Heat-shock Proteins

1999 • 89 citations

Caenorhabditis elegans small heat‐shock proteins Hsp12.2 and Hsp12.3 form tetramers and have no chaperone‐like activity

1998 • 77 citations

Distinguishing Helix Conformations in Alanine-Rich Peptides Using the Unnatural Amino Acid TOAC and Electron Spin Resonance

1996 • 76 citations

Site-Directed Spin-Labeling Study of the Structure and Subunit Interactions along a Conserved Sequence in the α-Crystallin Domain of Heat-Shock Protein 27. Evidence of a Conserved Subunit Interface

1997 • 55 citations

Identification of Protein Folding Patterns Using Site-Directed Spin Labeling. Structural Characterization of a β-Sheet and Putative Substrate Binding Regions in the Conserved Domain of αA-Crystallin

1998 • 52 citations

Resolved Electron-Electron Spin-Spin Splittings in EPR Spectra

1989 • 46 citations

Protein folding and misfolding inside and outside the cell

1998 • 43 citations

The function of heat-shock proteins in stress tolerance.

1994 • 42 citations

Chapter 29 Molecular studies of prion diseases

1998 • 39 citations

α- C-terminal domain: on the track of an Ig fold

1998 • 29 citations