Ion efflux systems involved in bacterial metal resistances

The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene

1993 • 1,905 citations

Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper–transporting ATPase

1993 • 1,395 citations

A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport

1993 • 939 citations

Alcaligenes eutrophus CH34 is a facultative chemolithotroph with plasmid-bound resistance to heavy metals

1985 • 798 citations

Isolation of a candidate gene for Menkes disease that encodes a potential heavy metal binding protein

1993 • 720 citations

Isolation of a partial candidate gene for Menkes disease by positional cloning

1993 • 690 citations

Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon

1993 • 685 citations

ABC transporters: bacterial exporters

1993 • 607 citations

High specificity of a phosphate transport protein determined by hydrogen bonds

1990 • 525 citations

Molecular cloning and characterization of acrA and acrE genes of Escherichia coli

1993 • 459 citations

Plasmid-linked Resistance to Inorganic Salts in Staphylococcus aureus

1968 • 406 citations

Primary structure of two P-type ATPases involved in copper homeostasis in Enterococcus hirae

1993 • 379 citations

Gene regulation of plasmid- and chromosome-determined inorganic ion transport in bacteria

1992 • 369 citations

Resistance to cadmium, cobalt, zinc, and nickel in microbes

1992 • 367 citations

Two novel families of bacterial membrane proteins concerned with nodulation, cell division and transport

1994 • 360 citations

Cadmium resistance from Staphylococcus aureus plasmid pI258 cadA gene results from a cadmium-efflux ATPase.

1989 • 340 citations

Two systems for the uptake of phosphate in Escherichia coli

1977 • 329 citations

Wilson disease and Menkes disease: new handles on heavy-metal transport

1994 • 326 citations

Nucleotide sequence of the structural genes for an anion pump. The plasmid-encoded arsenical resistance operon.

1986 • 324 citations

Multidrug resistance pumps in bacteria: variations on a theme

1994 • 314 citations

Expression and nucleotide sequence of a plasmid-determined divalent cation efflux system from Alcaligenes eutrophus.

1989 • 286 citations

Phosphate metabolism and cellular regulation in microorganisms

1988 • 274 citations

Reduction of arsenate to arsenite by the ArsC protein of the arsenic resistance operon of Staphylococcus aureus plasmid pI258.

1992 • 273 citations

Computer-aided analyses of transport protein sequences: gleaning evidence concerning function, structure, biogenesis, and evolution

1994 • 263 citations

Penicillinase plasmids of Staphylococcus aureus: Restriction-deletion maps

1979 • 251 citations

Regulation and expression of the arsenic resistance operon from Staphylococcus aureus plasmid pI258

1992 • 248 citations

Characterization of two genetically separable inorganic phosphate transport systems in Escherichia coli

1980 • 233 citations

Characterization of the inducible nickel and cobalt resistance determinant cnr from pMOL28 of Alcaligenes eutrophus CH34

1993 • 223 citations

Combined nickel-cobalt-cadmium resistance encoded by the ncc locus of Alcaligenes xylosoxidans 31A

1994 • 213 citations

Inducible plasmid-determined resistance to arsenate, arsenite, and antimony (III) in escherichia coli and Staphylococcus aureus

1981 • 212 citations

ABC transporters: bacterial exporters.

1993 • 210 citations

Plasmid-determined inducible efflux is responsible for resistance to cadmium, zinc, and cobalt in Alcaligenes eutrophus

1989 • 205 citations

COT1, a Gene Involved in Cobalt Accumulation in Saccharomyces cerevisiae

1992 • 202 citations

Properties of the Arsenate Reductase of Plasmid R773

1994 • 201 citations

Identification of a gene conferring resistance to zinc and cadmium ions in the yeast Saccharomyces cerevisiae

1989 • 197 citations

Molecular aspects of phosphate transport in Escherichia coli

1990 • 188 citations

CzcR and CzcD, gene products affecting regulation of resistance to cobalt, zinc, and cadmium (czc system) in Alcaligenes eutrophus

1992 • 185 citations

Energy-dependent efflux of cadmium coded by a plasmid resistance determinant in Staphylococcus aureus

1981 • 184 citations

Cloning of plasmid genes encoding resistance to cadmium, zinc, and cobalt in Alcaligenes eutrophus CH34

1987 • 183 citations

Metalloregulated expression of the ars operon.

1993 • 181 citations

Decreased chromate uptake in Pseudomonas fluorescens carrying a chromate resistance plasmid

1987 • 180 citations

Bacterial resistance ATPases: primary pumps for exporting toxic cations and anions

1989 • 179 citations

Expression and regulation of the antimonite, arsenite, and arsenate resistance operon of Staphylococcus xylosus plasmid pSX267

1992 • 177 citations

P-type ATPases of eukaryotes and bacteria: Sequence analyses and construction of phylogenetic trees

1994 • 177 citations

Nucleotide sequence and expression of a plasmid-encoded chromate resistance determinant from Alcaligenes eutrophus.

1990 • 177 citations

The ArsR protein is a trans‐acting regulatory protein

1991 • 176 citations

Molecular characterization of an anion pump. The ArsB protein is the membrane anchor for the ArsA protein.

1990 • 152 citations

Mechanism of light-dependent proton translocation by bacteriorhodopsin

1993 • 150 citations

COT1, a gene involved in cobalt accumulation in Saccharomyces cerevisiae.

1992 • 150 citations

Molecular characterization of an anion pump. The arsA gene product is an arsenite(antimonate)-stimulated ATPase.

1988 • 149 citations

Arsenate reduction mediated by the plasmid‐encoded ArsC protein is coupled to glutathione

1994 • 149 citations

Membrane topology of the ArsB protein, the membrane subunit of an anion-translocating ATPase.

1992 • 146 citations

Plasmid-borne cadmium resistance genes in Listeria monocytogenes are similar to cadA and cadC of Staphylococcus aureus and are induced by cadmium

1994 • 144 citations

Cloning, nucleotide sequence, and expression of the chromate resistance determinant of Pseudomonas aeruginosa plasmid pUM505

1990 • 143 citations

Arsenate Reductase of Staphylococcus aureus Plasmid pI258

1994 • 143 citations

Effect of arsenate on inorganic phosphate transport in Escherichia coli

1980 • 143 citations

Energetics of plasmid-mediated arsenate resistance in Escherichia coli.

1982 • 140 citations

luxABgene fusions with the arsenic and cadmium resistance operons ofStaphylococcus aureusplasmid pI258

1993 • 136 citations

Energy-dependent arsenate efflux: the mechanism of plasmid-mediated resistance.

1982 • 132 citations

Reduced cadmium transport determined by a resistance plasmid in Staphylococcus aureus

1981 • 130 citations

The arsD gene encodes a second trans‐acting regulatory protein of the plasmid‐encoded arsenical resistance operon

1993 • 120 citations

Mutations in the murine homologue of the Menkes gene in dappled and blotchy mice

1994 • 119 citations

From cell membrane to nucleotides: The phosphate regulon in Escherichia coli

1990 • 117 citations

Cloning and expression of plasmid genes encoding resistances to chromate and cobalt in Alcaligenes eutrophus

1989 • 115 citations

Cadmium and manganese transport in Staphylococcus aureus membrane vesicles

1982 • 107 citations

ATP-dependent cadmium transport by the cadA cadmium resistance determinant in everted membrane vesicles of Bacillus subtilis

1992 • 104 citations

Regulation of the cadA cadmium resistance determinant of Staphylococcus aureus plasmid pI258

1991 • 102 citations

A second gene in the Staphylococcus aureus cadA cadmium resistance determinant of plasmid pI258

1991 • 98 citations

Metal ion uptake by a plasmid-free metal-sensitive Alcaligenes eutrophus strain

1989 • 97 citations

Anion-exchange mechanisms in bacteria

1990 • 97 citations

A plasmid-encoded arsenite pump produces arsenite resistance in Escherichia coli

1984 • 92 citations

Plasmid-borne cadmium resistance genes in Listeria monocytogenes are present on Tn5422, a novel transposon closely related to Tn917

1994 • 92 citations

Structural evolution of the annexin supergene family

1994 • 88 citations

SITE-DIRECTED MUTAGENESIS AND ION-GRADIENT DRIVEN ACTIVE TRANSPORT: On the Path of the Proton

1988 • 83 citations

Computer-aided analyses of transport protein sequences: gleaning evidence concerning function, structure, biogenesis, and evolution.

1994 • 81 citations

Arsenic efflux governed by the arsenic resistance determinant of Staphylococcus aureus plasmid pI258

1993 • 78 citations

Cation Transport Alteration Associated with Plasmid-Determined Resistance to Cadmium in Staphylococcus aureus

1978 • 76 citations

Human Menkes X‐chromosome disease and the staphylococcal cadmium‐resistance ATPase: a remarkable similarity in protein sequences

1993 • 76 citations

Orphan enzyme or patriarch of a new tribe: the arsenic resistance ATPase of bacterial plasmids

1993 • 73 citations

Determinants Encoding Resistance to Several Heavy Metals in Newly Isolated Copper-Resistant Bacteria

1991 • 72 citations

Phosphate transport in Pseudomonas aeruginosa. Involvement of a periplasmic phosphate-binding protein

1984 • 70 citations

Identification of the membrane component of the anion pump encoded by the arsenical resistance operon of R‐factor R773

1989 • 70 citations

Arsenate resistant mutants of and phosphate transport

1970 • 68 citations

Plasmid pMOL28-encoded resistance to nickel is due to specific efflux

1988 • 67 citations

Cloning of pMOL28-encoded nickel resistance genes and expression of the genes in Alcaligenes eutrophus and Pseudomonas spp

1989 • 67 citations

A new type of Alcaligenes eutrophus CH34 zinc resistance generated by mutations affecting regulation of the cnr cobalt-nickel resistance system

1993 • 63 citations

Phosphate Transport in Prokaryotes

1987 • 57 citations

Energy-Dependent Zinc Transport by Escherichia coli

1974 • 56 citations

The arsenical ATPase efflux pump mediates tellurite resistance

1992 • 56 citations

Mutagenesis of the C-terminal nucleotide-binding site of an anion-translocating ATPase.

1992 • 55 citations

Interaction of Arsenate with Phosphate-Transport Systems in Wild-Type and Mutant Streptococcus faecalis

1966 • 53 citations

Molecular cloning and nucleotide sequence of the glycogen branching enzyme gene (glgB) from Bacillus stearothermophilus and expression in Escherichia coli and Bacillus subtilis

1991 • 51 citations

Anion-exchange mechanisms in bacteria.

1990 • 50 citations

Formation of a Phosphorylated Enzyme Intermediate by the cadA Cd2+-ATPase

1993 • 50 citations

Energy-dependent arsenate flux: the mechaism of plasmid-mediated resistance

1982 • 49 citations

Phosphorus Assimilation and Its Control of Gene Expression in Escherichia coli

1990 • 48 citations

Mercuric Ion Binding Abilities of MerP Variants Containing Only One Cysteine

1993 • 44 citations

Complementation between nucleotide binding domains in an anion-translocating ATPase

1993 • 42 citations

Substrate-induced dimerization of the ArsA protein, the catalytic component of an anion-translocating ATPase

1991 • 34 citations

A possible mechanism for metal-ion induced DNA-protein dissociation in a family of prokaryotic transcriptional regulators

1993 • 34 citations

Plasmid pMOL28-mediated inducible nickel resistance inAlcaligenes eutrophusstrain CH34

1987 • 32 citations

1H NMR studies of the mercuric ion binding protein MerP: Sequential assignment, secondary structure and global fold of oxidized MerP

1993 • 30 citations

TheglgBgene from the thermophileBacillus caldolyticusencodes a thermolabile branching enzyme

1992 • 29 citations

Trinitrophenyl-ATP binding to the ArsA protein: The catalytic subunit of an anion pump

1991 • 24 citations

In vitro assembly of an anion-stimulated ATPase from peptide fragments

1994 • 14 citations

What The Papers Say: Topoisomerase II can relax; novobiocin is a mitochondrial poison after all

1990 • 9 citations

Deleted Work

1955 • 0 citations