N- and P-type Ca2+ channels are involved in acetylcholine release at a neuroneuronal synapse: only the N-type channel is the target of neuromodulators.

Dominant Role of N-Type Ca ²⁺ Channels in Evoked Release of Norepinephrine from Sympathetic Neurons

1988 • 859 citations

Distinctive pharmacology and kinetics of cloned neuronal Ca2+ channels and their possible counterparts in mammalian CNS neurons

1993 • 635 citations

Blocking and isolation of a calcium channel from neurons in mammals and cephalopods utilizing a toxin fraction (FTX) from funnel-web spider poison.

1989 • 631 citations

P-type voltage-dependent calcium channel mediates presynaptic calcium influx and transmitter release in mammalian synapses.

1992 • 400 citations

Distribution and functional significance of the P-type, voltage-dependent Ca2+ channels in the mammalian central nervous system

1992 • 335 citations

Brain voltage-sensitive calcium channel subtypes differentiated by omega-conotoxin fraction GVIA.

1986 • 307 citations

Multiple calcium channels mediate neurotransmitter release from peripheral neurons.

1986 • 288 citations

Calcium channels in rat brain synaptosomes: identification and pharmacological characterization. High affinity blockade by organic Ca2+ channel blockers

1985 • 218 citations

Effects of 4-aminopyridine on potassium currents in a molluscan neuron.

1981 • 204 citations

Dihydropyridine‐sensitive and omega‐conotoxin‐sensitive calcium channels in a mammalian neuroblastoma‐glioma cell line.

1992 • 181 citations

Pharmacological dissection of receptor-associated and voltage-sensitive ionic channels involved in catecholamine release

1983 • 155 citations

Inhibition of central neurotransmitter release by ?-conotoxin GVIA, a peptide modulator of the N-type voltage-sensitive calcium channel

1987 • 147 citations

Contributions of Two Types of Calcium Channels to Synaptic Transmission and Plasticity

1990 • 132 citations

The effect of omega conotoxin GVIA, a peptide modulator of the N-type voltage sensitive calcium channels, on motor responses produced by activation of efferent and sensory nerves in mammalian smooth muscle

1988 • 112 citations

Neurochemical evidence for the involvement of N-type calcium channels in transmitter secretion from peripheral endings of sensory nerves in guinea pigs

1990 • 111 citations

Expression of diverse neuropeptide cotransmitters by identified motor neurons in Aplysia

1991 • 108 citations

The effect of ω‐conotoxin GVIA on synaptic transmission within the nucleus accumbens and hippocampus of the rat in vitro

1991 • 102 citations

Effects of ω‐conotoxin GVIA on autonomic neuroeffector transmission in various tissues

1990 • 102 citations

Kinetics of calcium‐dependent inactivation of calcium current in voltage‐clamped neurones of Aplysia californica.

1984 • 95 citations

Inhibition of noradrenaline release by ω‐conotoxin GVIA in the rat tail artery

1989 • 80 citations

Differential effects of calcium channel antagonists (?-conotoxin GVIA, nifedipine, verapamil) on the electrically-evoked release of [3H]acetylcholine from the myenteric plexus, phrenic nerve and neocortex of rats

1990 • 75 citations

ω-Conotoxin GVIA and pharmacological modulation of hippocampal noradrenaline release

1988 • 71 citations

ω‐Conotoxin GVIA is a potent inhibitor of sympathetic neurogenic responses in rat small mesenteric arteries

1990 • 68 citations

Evidence for two independent modes of activation of the ‘efferent’ function of capsaicin-sensitive nerves

1988 • 66 citations

Properties of Calcium Channels Isolated with Spider Toxin, FTX

1991 • 58 citations

Differential effect of ω‐conotoxin on release of the adrenergic transmitter and the vasoconstrictor response to noradrenaline in the rat isolated kidney

1988 • 57 citations

Inhibition of norepinephrine and acetylcholine release from human neocortex by omega-conotoxin GVIA.

1990 • 56 citations

Evidence of ω-conotoxin GV1A-sensitive Ca2+ channels in mammalian peripheral nerve terminals

1988 • 48 citations

Characterization of the effects of ω‐conotoxin GVIA on the responses of voltage‐sensitive calcium channels

1989 • 45 citations

Presynaptic calcium concentration microdomains and transmitter release

1992 • 44 citations

Calcium current modulation in frog sympathetic neurones: L‐current is relatively insensitive to neurotransmitters.

1992 • 42 citations

ω-Conotoxin GVIA and dihydropyridines discriminate two types of Ca2+ channels involved in GABA release from striatal neurons in culture

1990 • 39 citations

Histamine and FLRFamide regulate acetylcholine release at an identified synapse in Aplysia in opposite ways.

1990 • 34 citations

Activation of protein kinase C by presynaptic FLRFamide receptors facilitates transmitter release at an aplysia cholinergic synapse

1990 • 28 citations

Presynaptic actions of curare and atropine on quantal acetylcholine release at a central synapse of Aplysia.

1987 • 26 citations

Involvement of Ca2+ uptake by a reticulum-like store in the control of transmitter release

1992 • 24 citations

Differential sensitivities of avian and mammalian neuromuscular junctions to inhibition of cholinergic transmission by ω-conotoxin GVIA

1991 • 23 citations

Agelenopsis aperta venom and FTX, a purified toxin, inhibit acetylcholine release in Torpedo synaptosomes

1993 • 20 citations

Involvement of Calcium Channels in Depolarization‐Evoked Release of Adenosine from Spinal Cord Synaptosomes

1993 • 19 citations

Omega-conotoxin-sensitive calcium channels modulate autonomic neurotransmission in guinea pig airways.

1992 • 17 citations

Transmitter release and calcium currents at an Aplysia buccal ganglion synapse—I. Characterization

1993 • 15 citations

Transmitter release and calcium currents at an Aplysia buccal ganglion synapse—II. Modulation by presynaptic receptors

1993 • 13 citations

Pre- and postsynaptic actions of nifedipine at an identified cholinergic central synapse of Aplysia

1992 • 8 citations